Disclosing common biological signatures and predicting new therapeutic targets in schizophrenia and obsessive–compulsive disorder by integrated bioinformatics analysis
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[1] S. Brand,et al. Identification of key long non-coding RNA-associated competing endogenous RNA axes in Brodmann Area 10 brain region of schizophrenia patients , 2022, Frontiers in Psychiatry.
[2] S. Pençe,et al. Can miRNA Expression Levels Predict Treatment Resistance to Serotonin Reuptake Inhibitors in Patients with Obsessive-Compulsive Disorder? , 2022, Psychiatry and Clinical Psychopharmacology.
[3] A. Merikangas,et al. What genes are differentially expressed in individuals with schizophrenia? A systematic review , 2022, Molecular Psychiatry.
[4] F. Alizadeh,et al. Serotonin transporter functional polymorphisms potentially increase risk of schizophrenia separately and as a haplotype , 2022, Scientific Reports.
[5] Yanqing Liu,et al. Altered expression levels of miR-144-3p and ATP1B2 are associated with schizophrenia , 2022, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
[6] Tudor I. Oprea,et al. Getting Started with the IDG KMC Datasets and Tools , 2022, Current protocols.
[7] Kimberly Burns,et al. Pharmacological and philosophical considerations for the around-the-clock use of scheduled melatonin to promote sedation and reduce aggression in individuals with serious mental illness: a case report , 2021, International clinical psychopharmacology.
[8] N. Bokhan,et al. Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms , 2021, Life.
[9] D. Castle,et al. Therapeutic use of melatonin in schizophrenia: A systematic review , 2021, World journal of psychiatry.
[10] P. Asgari,et al. Treatment Approaches Based on Neuroscientific Data in Patients With Obsessive-Compulsive Disorder , 2021, International Clinical Neuroscience Journal.
[11] T. Werge,et al. Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis , 2021, Frontiers in Genetics.
[12] Henning Hermjakob,et al. IntAct App: a Cytoscape application for molecular interaction network visualization and analysis , 2021, Bioinform..
[13] Mo Li,et al. Genome-wide association study of antipsychotic-induced sinus bradycardia in Chinese schizophrenia patients , 2021, PloS one.
[14] Kathleen M. Jagodnik,et al. Gene Set Knowledge Discovery with Enrichr , 2021, Current protocols.
[15] R. Maiti,et al. Effect of Haloperidol and Risperidone on Serum Melatonin and GAP-43 in Patients with Schizophrenia: A Prospective Cohort Study , 2021, Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology.
[16] A. Shahbazi,et al. A Computational-Based Drug Repurposing Method Targeting SARS-CoV-2 and its Neurological Manifestations Genes and Signaling Pathways , 2021, Bioinformatics and biology insights.
[17] J. Wan,et al. Construction of lncRNA-related ceRNA regulatory network in diabetic subdermal endothelial cells , 2021, Bioengineered.
[18] Nadezhda T. Doncheva,et al. The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets , 2020, Nucleic Acids Res..
[19] S. Deshpande,et al. Schizophrenia with and without obsessive-compulsive symptoms: a comparative analysis of performance on trail making test and disability on WHODAS , 2020, General Psychiatry.
[20] Mohammad Safiqul Islam,et al. Association of DRD2 gene polymorphisms with schizophrenia in the young Bangladeshi population: A pilot study , 2020, Heliyon.
[21] G. Hall,et al. The association of HTR2A polymorphisms with obsessive-compulsive disorder and its subtypes: A meta-analysis. , 2020, Journal of affective disorders.
[22] A. Bozorgmehr,et al. An integrative gene network-based approach to uncover the cellular and molecular infrastructures of schizophrenia. , 2020, Life sciences.
[23] Ming Xu,et al. MiR-3121-3p promotes tumor invasion and metastasis by suppressing Rap1GAP in papillary thyroid cancer in vitro , 2020, Annals of translational medicine.
[24] J. Kantrowitz,et al. Targeting Serotonin 5-HT2A Receptors to Better Treat Schizophrenia: Rationale and Current Approaches , 2020, CNS Drugs.
[25] K. Hong,et al. Clozapine generates obsessive compulsive disorder-like behavior in mice , 2020, Molecular Brain.
[26] A. V. van Balkom,et al. Classification of comorbidity in obsessive–compulsive disorder: A latent class analysis , 2020, Brain and behavior.
[27] A. Bozorgmehr,et al. How obsessive–compulsive and bipolar disorders meet each other? An integrative gene-based enrichment approach , 2020, Annals of General Psychiatry.
[28] A. Merikangas,et al. Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders , 2020, Genes, brain, and behavior.
[29] N. Pivac,et al. HTR1A, HTR1B, HTR2A, HTR2C and HTR6 Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia , 2020, International journal of molecular sciences.
[30] W. Honer,et al. Clozapine-Associated Obsessive-Compulsive Symptoms and Their Management: A Systematic Review and Analysis of 107 Reported Cases , 2019, Psychotherapy and Psychosomatics.
[31] Zieske Maritska,et al. DRD2 Gene Polymorphisms in Schizophrenia Patients , 2020, Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia.
[32] Jun Yao,et al. A Meta-analysis of the Association Between SLC6A3 Gene Polymorphisms and Schizophrenia , 2019, Journal of Molecular Neuroscience.
[33] Pradeep Kumar,et al. Catechol-O-methyltransferase gene Val158Met polymorphism and obsessive compulsive disorder susceptibility: a meta-analysis , 2019, Metabolic Brain Disease.
[34] P. Srivastava,et al. Analysis and subsequent molecular docking of selected phytochemicals with SLC6A3 and SLC6A4 as potential therapeutic agents for Obsessive-Compulsive Disorder (OCD) , 2019 .
[35] B. Pignon,et al. Obsessive-Compulsive Symptoms in Schizophrenia: an Up-To-Date Review of Literature , 2019, Current Psychiatry Reports.
[36] P. Yan,et al. Is Brain-Derived Neurotrophic Factor (BDNF) Val66Met Polymorphism Associated with Obsessive-Compulsive Disorder? A Meta-Analysis. , 2019, Psychiatria Danubina.
[37] R. Edden,et al. Investigation of anterior cingulate cortex gamma-aminobutyric acid and glutamate-glutamine levels in obsessive-compulsive disorder using magnetic resonance spectroscopy , 2019, BMC Psychiatry.
[38] J. Coyle,et al. Glutamate hypothesis in schizophrenia , 2019, Psychiatry and clinical neurosciences.
[39] K. Turkmani,et al. Haloperidol discontinuation for people with schizophrenia. , 2019, The Cochrane database of systematic reviews.
[40] T. Jaisoorya,et al. Antipsychotic augmentation in the treatment of obsessive-compulsive disorder , 2019, Indian journal of psychiatry.
[41] Jun Yao,et al. Association between the SLC6A4 gene and schizophrenia: an updated meta-analysis , 2018, Neuropsychiatric disease and treatment.
[42] B. Camarena,et al. Association study between COMT, DRD2, and DRD3 gene variants and antipsychotic treatment response in Mexican patients with schizophrenia , 2018, Neuropsychiatric disease and treatment.
[43] Jihan Wang,et al. Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia , 2018, Psychiatry Research.
[44] Neda Jahanshad,et al. Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen. , 2018, The British journal of psychiatry : the journal of mental science.
[45] S. Stahl. Beyond the dopamine hypothesis of schizophrenia to three neural networks of psychosis: dopamine, serotonin, and glutamate , 2018, CNS Spectrums.
[46] A. Mohammadi,et al. Brain, blood, cerebrospinal fluid, and serum biomarkers in schizophrenia , 2018, Psychiatry Research.
[47] R. Emsley,et al. The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder , 2018, Molecular and Cellular Neuroscience.
[48] Leonardo Franklin Fontenelle,et al. Association analysis of SLC6A4 and HTR2A genes with obsessive-compulsive disorder: Influence of the STin2 polymorphism. , 2018, Comprehensive psychiatry.
[49] M. Pompili,et al. Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine , 2018, Therapeutic advances in drug safety.
[50] J. Parent,et al. PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors , 2018, Cell reports.
[51] A. Ahmadiani,et al. Association of the functional serotonin transporter haplotype with familial form of obsessive compulsive disorder in Iranian patients , 2018, International journal of psychiatry in clinical practice.
[52] C. Burton,et al. A review of the role of serotonin system genes in obsessive-compulsive disorder , 2017, Neuroscience & Biobehavioral Reviews.
[53] Lin He,et al. MiRNAs of peripheral blood as the biomarker of schizophrenia , 2017, Hereditas.
[54] Sang-Yoon Lee,et al. Altered interregional correlations between serotonin transporter availability and cerebral glucose metabolism in schizophrenia: A high-resolution PET study using [11C]DASB and [18F]FDG , 2017, Schizophrenia Research.
[55] Tih-Shih Lee,et al. GAD1 Gene Expression in Blood of Patients with First-Episode Psychosis , 2017, PloS one.
[56] C. Pariante,et al. The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders , 2016, Translational psychiatry.
[57] F. Lee,et al. The Role of BDNF in the Development of Fear Learning , 2016, Depression and anxiety.
[58] Scott J. Myers,et al. Human GRIN2B variants in neurodevelopmental disorders , 2016, Journal of pharmacological sciences.
[59] G. He,et al. A study of single nucleotide polymorphisms of GRIN2B in schizophrenia from Chinese Han population , 2016, Neuroscience Letters.
[60] Andrew D. Rouillard,et al. The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins , 2016, Database J. Biol. Databases Curation.
[61] X. Estivill,et al. Exon-focused genome-wide association study of obsessive-compulsive disorder and shared polygenic risk with schizophrenia , 2016, Translational Psychiatry.
[62] Seshadri Sekhar Chatterjee,et al. Emerging Hyperprolactinemic Galactorrhea in Obsessive Compulsive Disorder with a Stable Dose of Fluoxetine , 2015, Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology.
[63] S. Selek,et al. Microribonucleic acid dysregulations in children and adolescents with obsessive–compulsive disorder , 2015, Neuropsychiatric disease and treatment.
[64] Ming-dao Zhang,et al. Augmentation with antidepressants in schizophrenia treatment: benefit or risk , 2015, Neuropsychiatric disease and treatment.
[65] R. Quartesan,et al. History and Conceptual Problems of the Relationship Between Obsessions and Hallucinations , 2015, Harvard review of psychiatry.
[66] Yuhan Wang,et al. microRNAs as novel biomarkers of schizophrenia (Review) , 2014, Experimental and therapeutic medicine.
[67] D. Atkinson,et al. Schizophrenia: overview and treatment options. , 2014, P & T : a peer-reviewed journal for formulary management.
[68] M. Zink. Comorbid Obsessive-Compulsive Symptoms in Schizophrenia: Insight into Pathomechanisms Facilitates Treatment , 2014, Advances in medicine.
[69] K. Ohi,et al. Functional polymorphism (C‐824T) of the tyrosine hydroxylase gene affects IQ in schizophrenia , 2014, Psychiatry and clinical neurosciences.
[70] F. Smit,et al. The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates , 2014, Schizophrenia Research.
[71] Dimitris Mavridis,et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis , 2013, The Lancet.
[72] M. Zink,et al. Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors , 2013, Front. Pharmacol..
[73] G. Michlewski,et al. miRNAs in development and pathogenesis of the nervous system. , 2013, Biochemical Society transactions.
[74] S. Taylor,et al. Molecular genetics of obsessive–compulsive disorder: a comprehensive meta-analysis of genetic association studies , 2013, Molecular Psychiatry.
[75] R. Nieto,et al. BDNF and Schizophrenia: From Neurodevelopment to Neuronal Plasticity, Learning, and Memory , 2013, Front. Psychiatry.
[76] D. Cardinali,et al. Sleep and circadian rhythm dysregulation in schizophrenia , 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[77] S. E. Stewart,et al. Meta‐analysis of association between obsessive‐compulsive disorder and the 3′ region of neuronal glutamate transporter gene SLC1A1 , 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[78] Abraham Weizman,et al. Escitalopram in the treatment of patients with schizophrenia and obsessive–compulsive disorder: an open-label, prospective study , 2013, International clinical psychopharmacology.
[79] Z. J. Huang,et al. Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: Implications for schizophrenia , 2013, Neurobiology of Disease.
[80] M. Gratacós,et al. Association between the NMDA glutamate receptor GRIN2B gene and obsessive-compulsive disorder. , 2012, Journal of psychiatry & neuroscience : JPN.
[81] R. Quartesan,et al. Schizophrenia and obsessive-compulsive disorder: from comorbidity to schizo-obsessive disorder. , 2012, Rivista di psichiatria.
[82] K. Audenaert,et al. Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder , 2012, Psychiatry Research: Neuroimaging.
[83] Michael A. Langston,et al. GeneWeaver: a web-based system for integrative functional genomics , 2011, Nucleic Acids Res..
[84] A. Achim,et al. How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association. , 2011, Schizophrenia bulletin.
[85] Károly Mirnics,et al. ynaptic changes in the brain of subjects with schizophrenia , 2011 .
[86] Yong-Ku Kim,et al. Effect of Serotonin-Related Gene Polymorphisms on Pathogenesis and Treatment Response in Korean Schizophrenic Patients , 2011, Behavior genetics.
[87] Chia-Hsiang Chen,et al. Genetic and Functional Analysis of the DLG4 Gene Encoding the Post-Synaptic Density Protein 95 in Schizophrenia , 2010, PloS one.
[88] Chan-Hyung Kim,et al. Role of dopamine in the pathophysiology and treatment of obsessive–compulsive disorder , 2010, Expert review of neurotherapeutics.
[89] J. A. Boer,et al. The role of the brain‐derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive‐compulsive disorder (OCD) , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[90] A. Dasgupta,et al. Study of oxidative stress in obsessive compulsive disorder in response to treatment with Fluoxetine , 2009, Indian Journal of Clinical Biochemistry.
[91] Guoping Feng,et al. Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder , 2008, Current chemical genomics.
[92] Leonardo Franklin Fontenelle,et al. The Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders: recruitment, assessment instruments, methods for the development of multicenter collaborative studies and preliminary results. , 2008, Revista brasileira de psiquiatria.
[93] Alessandra Gorini,et al. In vivo PET study of 5HT2A serotonin and D2 dopamine dysfunction in drug-naive obsessive-compulsive disorder , 2008, NeuroImage.
[94] K. Martinowich,et al. Cell biology of BDNF and its relevance to schizophrenia. , 2008, Novartis Foundation symposium.
[95] K. Hornik,et al. Changes in Thalamus–Hypothalamus Serotonin Transporter Availability during Clomipramine Administration in Patients with Obsessive–Compulsive Disorder , 2008, Neuropsychopharmacology.
[96] D. Stein,et al. Investigating the role of the brain-derived neurotrophic factor (BDNF) val66met variant in obsessive-compulsive disorder (OCD) , 2008, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
[97] Keri Martinowich,et al. Interaction between BDNF and Serotonin: Role in Mood Disorders , 2008, Neuropsychopharmacology.
[98] Peter F. Buckley,et al. Neurotrophins and schizophrenia , 2007, Schizophrenia Research.
[99] H. Westenberg,et al. Association between the dopamine D2 receptor TaqI A2 allele and low activity COMT allele with obsessive–compulsive disorder in males , 2006, European Neuropsychopharmacology.
[100] S. Rasmussen,et al. The Brown Longitudinal Obsessive Compulsive Study: clinical features and symptoms of the sample at intake. , 2006, The Journal of clinical psychiatry.
[101] M. Richter,et al. Comorbidity and pathophysiology of obsessive-compulsive disorder in schizophrenia: is there evidence for a schizo-obsessive subtype of schizophrenia? , 2005, Journal of psychiatry & neuroscience : JPN.
[102] Abraham Weizman,et al. Obsessive-Compulsive Disorder in Schizophrenia , 2004 .
[103] M. Karayiorgou,et al. Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. , 2003, American journal of human genetics.
[104] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[105] J. Benson,et al. BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABAA receptor surface expression , 2001, The European journal of neuroscience.
[106] S. Rauch,et al. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. , 2000, The Psychiatric clinics of North America.
[107] P. Sokoloff,et al. Brain Derived Neurotrophic Factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia , 2000, Molecular Psychiatry.
[108] G. Rosoklija,et al. Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders: preliminary findings. , 2000, Archives of general psychiatry.
[109] Susumu Goto,et al. KEGG: Kyoto Encyclopedia of Genes and Genomes , 2000, Nucleic Acids Res..
[110] T. Pigott,et al. A review of the efficacy of selective serotonin reuptake inhibitors in obsessive-compulsive disorder. , 1999, The Journal of clinical psychiatry.
[111] M. Maj,et al. Decreased nocturnal secretion of melatonin in drug-free schizophrenics: no change after subchronic treatment with antipsychotics. , 1997, Neuropsychobiology.
[112] M. Maj,et al. Circadian rhythms of melatonin, cortisol and prolactin in patients with obsessive‐compulsive disorder , 1994, Acta psychiatrica Scandinavica.
[113] I. Nir,et al. Serum melatonin levels in schizophrenic and schizoaffective hospitalized patients , 1991, Acta psychiatrica Scandinavica.
[114] M. Marie-cardine,et al. Nocturnal plasma melatonin levels in schizophrenic patients , 1989, Biological Psychiatry.