A Meta Analysis of Pancreatic Microarray Datasets Yields New Targets as Cancer Genes and Biomarkers
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Chittibabu Guda | Xiaosheng Wang | C. Guda | Xiaosheng Wang | Nalin C. W. Goonesekere | N. Goonesekere | Lindsey Ludwig | Lindsey M. Ludwig
[1] C. Rancourt,et al. Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies , 2009, Journal of ovarian research.
[2] R. Tibshirani,et al. Disease signatures are robust across tissues and experiments , 2009, Molecular systems biology.
[3] H. Lee,et al. A synergistic interaction between transcription factors nuclear factor-κB and signal transducers and activators of transcription 3 promotes gastric cancer cell migration and invasion , 2013, BMC Gastroenterology.
[4] A. Matussek,et al. DNA promoter methylation status and protein expression of interleukin-8 in human colorectal adenocarcinomas , 2011, International Journal of Colorectal Disease.
[5] W. Jonat,et al. Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. , 2003, Cancer letters.
[6] F. Hsieh,et al. Clinicopathologic Correlation of Up-regulated Genes Identified Using cDNA Microarray and Real-time Reverse Transcription-PCR in Human Colorectal Cancer , 2005, Cancer Epidemiology Biomarkers & Prevention.
[7] Xin Lu,et al. Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis , 2009, Nature Medicine.
[8] Luis Serrano,et al. Correlation of mRNA and protein in complex biological samples , 2009, FEBS letters.
[9] Songying Zhang,et al. Calcium-binding protein S100P and cancer: mechanisms and clinical relevance , 2011, Journal of Cancer Research and Clinical Oncology.
[10] P. Scherle,et al. Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. , 2010, Trends in molecular medicine.
[11] Rainer Breitling,et al. Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments , 2004, FEBS letters.
[12] J. Diallo,et al. Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer. , 2007, Molecular cancer research : MCR.
[13] N. McGranahan,et al. The causes and consequences of genetic heterogeneity in cancer evolution , 2013, Nature.
[14] E. Elinav,et al. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms , 2013, Nature Reviews Cancer.
[15] Riccardo Colombo,et al. Synthesis and SAR of new pyrazolo[4,3-h]quinazoline-3-carboxamide derivatives as potent and selective MPS1 kinase inhibitors. , 2011, Bioorganic & medicinal chemistry letters.
[16] G. Parmigiani,et al. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.
[17] B. Christensen,et al. The relationship between tumor MSLN methylation and serum mesothelin (SMRP) in mesothelioma , 2011, Epigenetics.
[18] A. Levitzki,et al. Tyrphostins and other tyrosine kinase inhibitors. , 2006, Annual review of biochemistry.
[19] K. Franssila,et al. Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[20] C. Heizmann,et al. S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). , 2004, Biochemical and biophysical research communications.
[21] Leonard J Foster,et al. Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. , 2010, Cancer research.
[22] R. Hruban,et al. Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[23] K. Borden,et al. Mechanisms and insights into drug resistance in cancer , 2013, Front. Pharmacol..
[24] R. King,et al. When 2+2=5: the origins and fates of aneuploid and tetraploid cells. , 2008, Biochimica et biophysica acta.
[25] Aleksandar S. Dimovski,et al. Association of GPX1 polymorphism, GPX activity and prostate cancer risk , 2012, Human & experimental toxicology.
[26] D. Hunter,et al. Gene × Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study , 2006, BMC Cancer.
[27] Brian J. Smith,et al. Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase. , 2006, Human gene therapy.
[28] Rainer Breitling,et al. A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments , 2008, Bioinform..
[29] S. Serra,et al. The Use of Cytokeratin 19 (CK19) Immunohistochemistry in Lesions of the Pancreas, Gastrointestinal Tract, and Liver , 2010, Applied immunohistochemistry & molecular morphology : AIMM.
[30] Laurent Lessard,et al. Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study , 2005, British Journal of Cancer.
[31] S. Ishikawa,et al. Claudin-18 Is an Early-Stage Marker of Pancreatic Carcinogenesis , 2011, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[32] J. Pollack,et al. LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. , 2010, Cancer research.
[33] S. Leivonen,et al. Transforming growth factor‐β signaling in cancer invasion and metastasis , 2007, International journal of cancer.
[34] R. Srinivasan,et al. Major Molecular Markers in Pancreatic Ductal Adenocarcinoma and Their Roles in Screening, Diagnosis, Prognosis, and Treatment , 2011, Pancreas.
[35] C. Marson,et al. Histone deacetylase inhibitors: design, structure-activity relationships and therapeutic implications for cancer. , 2009, Anti-cancer agents in medicinal chemistry.
[36] S. Miknyoczki,et al. Discovery of small molecule c-Met inhibitors: Evolution and profiles of clinical candidates. , 2010, Anti-cancer agents in medicinal chemistry.
[37] M. Goto,et al. Mucins in human neoplasms: Clinical pathology, gene expression and diagnostic application , 2011, Pathology international.
[38] H. Hua,et al. Matrix metalloproteinases in tumorigenesis: an evolving paradigm , 2011, Cellular and Molecular Life Sciences.
[39] Andrea Musacchio,et al. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine , 2010, The Journal of cell biology.
[40] Martin A. Nowak,et al. Genetic Progression and the Waiting Time to Cancer , 2007, PLoS Comput. Biol..
[41] E. Motrescu,et al. Cancer cells, adipocytes and matrix metalloproteinase 11: a vicious tumor progression cycle , 2008, Biological chemistry.
[42] T. Barrette,et al. ONCOMINE: a cancer microarray database and integrated data-mining platform. , 2004, Neoplasia.
[43] T. Neumann,et al. AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness. , 2010, Biochemical and biophysical research communications.
[44] J. Habermann,et al. Serum biomarkers for improved diagnostic of pancreatic cancer: a current overview , 2011, Journal of Cancer Research and Clinical Oncology.
[45] F. Domann,et al. Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. , 2003, Neoplasia.
[46] J. Neoptolemos,et al. Comprehensive Analysis of Matrix Metalloproteinase and Tissue Inhibitor Expression in Pancreatic Cancer , 2004, Clinical Cancer Research.
[47] S. Batra,et al. Current status of molecular markers for early detection of sporadic pancreatic cancer. , 2011, Biochimica et biophysica acta.
[48] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[49] Gang Meng,et al. Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma. , 2008, Experimental and molecular pathology.
[50] P. Slattum,et al. Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors. , 2012, Bioorganic & medicinal chemistry letters.
[51] William R Sellers,et al. Linking somatic genetic alterations in cancer to therapeutics. , 2009, Current opinion in cell biology.
[52] Y. Miao,et al. The increase in the expression and hypomethylation of MUC4 gene with the progression of pancreatic ductal adenocarcinoma , 2011, Medical oncology.
[53] J. Diallo,et al. Regulation of IκB Kinase ε Expression by the Androgen Receptor and the Nuclear Factor-κB Transcription Factor in Prostate Cancer , 2007, Molecular Cancer Research.
[54] J. Cameron,et al. Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. , 2003, Cancer research.
[55] K. D. Sørensen,et al. Promoter hypomethylation and upregulation of trefoil factors in prostate cancer , 2010, International journal of cancer.
[56] Shizuo Akira,et al. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. , 2011, Cancer cell.
[57] D. Fisher,et al. A new era: melanoma genetics and therapeutics , 2011, The Journal of pathology.
[58] R. Flavell,et al. The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[59] N. Fausto. Hepatocyte growth factor receptor and the c-met oncogene Bottaro DP, Rubin JS, Faletto DL, Chan AM-L, Kmiecik TE, Vande Woude GF, Aaronson SA. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991;251:802?804 , 1991 .
[60] L. Buscail,et al. [New molecular targets in pancreatic cancer]. , 2008, Bulletin du cancer.
[61] Michele Magrane,et al. UniProt Knowledgebase: a hub of integrated protein data , 2011, Database J. Biol. Databases Curation.
[62] L. Tanoue. Cancer Statistics, 2009 , 2010 .
[63] Z. Werb,et al. Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.
[64] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[65] E. van Marck,et al. Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding. , 2006, Clinical cancer research : an official journal of the American Association for Cancer Research.
[66] M. Park,et al. Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3 , 2012, Archives of Pharmacal Research.
[67] M. Stratton. Exploring the Genomes of Cancer Cells: Progress and Promise , 2011, Science.
[68] Andrew Menzies,et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer , 2010, Nature.
[69] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[70] Guido Jenster,et al. Venn Mapping: clustering of heterologous microarray data based on the number of co-occurring differentially expressed genes , 2003, Bioinform..
[71] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[72] A. Jimeno,et al. Characterizing DNA methylation patterns in pancreatic cancer genome , 2009, Molecular oncology.
[73] S. Erkeland,et al. Retroviral insertion mutagenesis in mice as a comparative oncogenomics tool to identify disease genes in human leukemia. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.
[74] H. Yoshioka,et al. Epiplakin accelerates the lateral organization of keratin filaments during wound healing. , 2010, Journal of dermatological science.
[75] K. Tanabe,et al. Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity , 2006, Immunology.
[76] M. Reiss,et al. Targeting the Transforming Growth Factor-β pathway inhibits human basal-like breast cancer metastasis , 2010, Molecular Cancer.
[77] V. Regitz-Zagrosek,et al. The FASEB Journal • Research Communication Ahnak is critical for cardiac Ca(v)1.2 calcium channel function and its �-adrenergic regulation , 2022 .
[78] Rainer Breitling,et al. RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis , 2006, Bioinform..
[79] D. Goldenberg,et al. Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers , 2007, BMC Cancer.
[80] Jason Y. Park,et al. Molecular signatures of pancreatic cancer. , 2011, Archives of pathology & laboratory medicine.
[81] I. Salmon,et al. S100A2 is a predictive biomarker of adjuvant therapy benefit in pancreatic adenocarcinoma. , 2013, European journal of cancer.
[82] M. Nowak,et al. Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer , 2010, Nature.
[83] Christian Pilarsky,et al. Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes , 2005, Oncogene.
[84] L. Griffiths,et al. An Assessment of MMP and TIMP Gene Expression in Cell Lines and Stroma – Tumour Differences in MicrodissectedBreast Cancer Biopsies , 2003, Tumor Biology.
[85] M. Hermanová,et al. Expression of matrix metalloproteinases 3, 10 and 11 (stromelysins 1, 2 and 3) and matrix metalloproteinase 7 (matrilysin) by cancer cells in non-small cell lung neoplasms. Clinicopathologic studies. , 2006, Ceskoslovenska patologie.
[86] Kenoki Ohuchida,et al. S100P is a novel marker to identify intraductal papillary mucinous neoplasms. , 2010, Human pathology.
[87] Jingde Zhu,et al. CTHRC1 is upregulated by promoter demethylation and transforming growth factor‐β1 and may be associated with metastasis in human gastric cancer , 2012, Cancer science.
[88] A. Kutikhin,et al. Inherited variations in the SOD and GPX gene families and cancer risk , 2012, Free radical research.
[89] John Quackenbush,et al. Multiple-laboratory comparison of microarray platforms , 2005, Nature Methods.
[90] William C Hahn,et al. Oncogenic transformation and experimental models of human cancer. , 2008, Frontiers in bioscience : a journal and virtual library.
[91] Peter A. Jones,et al. A decade of exploring the cancer epigenome — biological and translational implications , 2011, Nature Reviews Cancer.
[92] S. Ghosh,et al. Signal transduction through NF-κB , 1998 .
[93] T. Barrette,et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. , 2007, Neoplasia.
[94] David M. Berman,et al. Tissue repair and stem cell renewal in carcinogenesis , 2004, Nature.
[95] C. Röcken,et al. Proteomics of Pancreatic Cancer , 2008, Pancreas.
[96] M. Hoenerhoff,et al. Inhibition of transforming growth factor-β-activated kinase-1 blocks cancer cell adhesion, invasion, and metastasis , 2012, British Journal of Cancer.
[97] G. Tortora,et al. LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis , 2008, Molecular Cancer Therapeutics.
[98] V. Dymicka-Piekarska,et al. Expression of matrix metalloproteinase 9 in pancreatic ductal carcinoma is associated with tumor metastasis formation. , 2007, Folia histochemica et cytobiologica.
[99] M. May,et al. Signal transduction through NF-kappa B. , 1998, Immunology today.
[100] J. Rubin,et al. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. , 1991, Science.
[101] G. Turashvili,et al. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis , 2007, BMC Cancer.
[102] Douglas G Altman,et al. Key Issues in Conducting a Meta-Analysis of Gene Expression Microarray Datasets , 2008, PLoS medicine.
[103] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[104] M. Moses,et al. Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[105] Taiping Zhang,et al. Advances in early diagnosis and therapy of pancreatic cancer. , 2011, Hepatobiliary & pancreatic diseases international : HBPD INT.
[106] S. Leivonen,et al. Transforming growth factor-beta signaling in cancer invasion and metastasis. , 2007, International journal of cancer.
[107] A. Siriwardena,et al. Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer. , 2007, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
[108] A. Jemal,et al. Cancer Statistics, 2009 , 2009, CA: a cancer journal for clinicians.
[109] F. Jiang,et al. The usefulness of S100P, mesothelin, fascin, prostate stem cell antigen, and 14‐3‐3 sigma in diagnosing pancreatic adenocarcinoma in cytological specimens obtained by endoscopic ultrasound guided fine‐needle aspiration , 2014, Diagnostic cytopathology.
[110] A. Amon,et al. Aneuploidy: cancer's fatal flaw? , 2009, Cancer research.
[111] N. S. Thomas,et al. Lck is a key target of imatinib and dasatinib in T-cell activation , 2010, Leukemia.
[112] Richard D Kolodner,et al. An overview of Cdk1-controlled targets and processes , 2010, Cell Division.
[113] M. Noguchi,et al. Tumorigenesis and Neoplastic Progression Aberrant Stratifin Overexpression Is Regulated by Tumor-Associated CpG Demethylation in Lung Adenocarcinoma , 2016 .
[114] J. Yanagisawa,et al. Global analysis of DNA methylation in early-stage liver fibrosis , 2012, BMC Medical Genomics.
[115] J. Cameron,et al. Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation. , 2002, The American journal of pathology.
[116] Emma Laing,et al. RankProdIt: A web-interactive Rank Products analysis tool , 2010, BMC Research Notes.
[117] Taebo Sim,et al. Small Molecule Kinase Inhibitors Provide Insight into Mps1 Cell Cycle Function , 2010, Nature chemical biology.
[118] Zhaoshen Li,et al. Proteomics in Pancreatic Cancer Research , 2011, International journal of proteomics.
[119] Paolo P. Provenzano,et al. Collagen reorganization at the tumor-stromal interface facilitates local invasion , 2006, BMC medicine.
[120] K. Ochi,et al. Matrix Metalloproteinase-2 in Pancreatic Juice for Diagnosis of Pancreatic Cancer , 2002, Pancreas.
[121] S. Ashley,et al. Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. , 2003, Surgery.
[122] A. Jankowska,et al. Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. , 2008, Blood.
[123] M. Martinka,et al. Aberrant Expression of Collagen Triple Helix Repeat Containing 1 in Human Solid Cancers , 2006, Clinical Cancer Research.
[124] R. Andersson,et al. Proteome-based biomarkers in pancreatic cancer. , 2011, World journal of gastroenterology.
[125] Yang Song,et al. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery , 2011, Nucleic Acids Res..
[126] S. S. Koh,et al. Claudin-4 overexpression is associated with epigenetic derepression in gastric carcinoma , 2011, Laboratory Investigation.
[127] B. Bauvois,et al. New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression. , 2012, Biochimica et biophysica acta.