Multiplexed protein measurement: technologies and applications of protein and antibody arrays

[1]  Leigh Anderson,et al.  Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins* , 2006, Molecular & Cellular Proteomics.

[2]  S. Kingsmore,et al.  Population Cohort Associating Chorioamnionitis, Cord Inflammatory Cytokines and Neurologic Outcome in Very Preterm, Extremely Low Birth Weight Infants , 2006, Pediatric Research.

[3]  I. Menown,et al.  Novel protein markers of acute coronary syndrome complications in low-risk outpatients: a systematic review of potential use in the emergency department. , 2005, Clinical chemistry.

[4]  Ann Eckersten,et al.  Integrated microfluidic compact disc device with potential use in both centralized and point-of-care laboratory settings. , 2005, Clinical chemistry.

[5]  Debashis Ghosh,et al.  Autoantibody signatures in prostate cancer. , 2005, The New England journal of medicine.

[6]  Axel Kowald,et al.  Profiling of Alopecia Areata Autoantigens Based on Protein Microarray Technology* , 2005, Molecular & Cellular Proteomics.

[7]  Bonnie Bruce,et al.  Antigen microarray profiling of autoantibodies in rheumatoid arthritis. , 2005, Arthritis and rheumatism.

[8]  Nasreen S Jessani,et al.  A streamlined platform for high-content functional proteomics of primary human specimens , 2005, Nature Methods.

[9]  A. Giuliani,et al.  Functional essentiality from topology features in metabolic networks: A case study in yeast , 2005, FEBS letters.

[10]  David E. Misek,et al.  Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis , 2005, BMC Cancer.

[11]  P. Bye,et al.  An Immunoproteomic Approach for Identification of Clinical Biomarkers for Monitoring Disease , 2005, Molecular & Cellular Proteomics.

[12]  Andrew Emili,et al.  Multidimensional protein identification technology (MudPIT): Technical overview of a profiling method optimized for the comprehensive proteomic investigation of normal and diseased heart tissue , 2005, Journal of the American Society for Mass Spectrometry.

[13]  D. Speicher,et al.  Depletion of multiple high‐abundance proteins improves protein profiling capacities of human serum and plasma , 2005, Proteomics.

[14]  D. Speicher,et al.  A novel four‐dimensional strategy combining protein and peptide separation methods enables detection of low‐abundance proteins in human plasma and serum proteomes , 2005, Proteomics.

[15]  Gilbert S Omenn,et al.  Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry data , 2005, Proteomics.

[16]  E. Klipp,et al.  Integrative model of the response of yeast to osmotic shock , 2005, Nature Biotechnology.

[17]  H. Pfister,et al.  Patterns of protein expression in infectious meningitis: A cerebrospinal fluid protein array analysis , 2005, Journal of Neuroimmunology.

[18]  Carole Foy,et al.  A comparability study of the emerging protein array platforms with established ELISA procedures. , 2005, Journal of immunological methods.

[19]  Martin A. Nowak,et al.  Dynamics of chronic myeloid leukaemia , 2005, Nature.

[20]  H. Tanke,et al.  A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera. , 2005, Journal of immunological methods.

[21]  Y. Shoenfeld,et al.  Evaluation of the BioPlex™ 2200 ANA Screen: Analysis of 510 Healthy Subjects: Incidence of Natural/Predictive Autoantibodies , 2005, Annals of the New York Academy of Sciences.

[22]  Ruifu Yang,et al.  Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine , 2005, Infection and Immunity.

[23]  Dieter Stoll,et al.  Protein microarrays for antibody profiling: Specificity and affinity determination on a chip , 2005, Proteomics.

[24]  Hongyu Zhao,et al.  Serum protein markers for early detection of ovarian cancer. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[25]  E. Petricoin,et al.  Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[26]  K. Büssow,et al.  Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. , 2005, The Journal of clinical investigation.

[27]  C. McLaughlin,et al.  Development of a sensitive, colorometric microarray assay for allergen-responsive human IgE. , 2005, Journal of immunological methods.

[28]  Jürgen Kreutzberger,et al.  Bacterial protein microarrays for identification of new potential diagnostic markers for Neisseria meningitidis infections , 2005, Proteomics.

[29]  K. Sachs,et al.  Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data , 2005, Science.

[30]  H. Soares,et al.  Method Validation and Measurement of Biomarkers in Nonclinical and Clinical Samples in Drug Development: A Conference Report , 2005, Pharmaceutical Research.

[31]  P. Utz Protein arrays for studying blood cells and their secreted products , 2005, Immunological reviews.

[32]  Brian B Haab,et al.  Antibody Arrays in Cancer Research , 2005, Molecular & Cellular Proteomics.

[33]  David Krumholz,et al.  Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: angiogenin and other defense system constituents. , 2005, Investigative ophthalmology & visual science.

[34]  P. Sorger A reductionist's systems biology: opinion. , 2005, Current opinion in cell biology.

[35]  S. Kingsmore,et al.  Protein Microarray Analysis of Disease Activity in Pediatric Inflammatory Bowel Disease Demonstrates Elevated Serum PLGF, IL-7, TGF-β1, and IL-12p40 Levels in Crohn's Disease and Ulcerative Colitis Patients in Remission versus Active Disease , 2005, The American Journal of Gastroenterology.

[36]  Jeffrey S. Morris,et al.  The importance of experimental design in proteomic mass spectrometry experiments: some cautionary tales. , 2005, Briefings in functional genomics & proteomics.

[37]  Pierre Baldi,et al.  Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[38]  G. Hortin Can mass spectrometric protein profiling meet desired standards of clinical laboratory practice? , 2005, Clinical chemistry.

[39]  LT Perlee,et al.  Development and standardization of multiplexed antibody microarrays for use in quantitative proteomics , 2004, Proteome Science.

[40]  Chi-Huey Wong,et al.  Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[41]  Jos Joore,et al.  Kinome Profiling for Studying Lipopolysaccharide Signal Transduction in Human Peripheral Blood Mononuclear Cells* , 2004, Journal of Biological Chemistry.

[42]  S. Kingsmore,et al.  Human Ribonuclease A Superfamily Members, Eosinophil-Derived Neurotoxin and Pancreatic Ribonuclease, Induce Dendritic Cell Maturation and Activation1 , 2004, The Journal of Immunology.

[43]  Michael P Washburn,et al.  Utilisation of proteomics datasets generated via multidimensional protein identification technology (MudPIT). , 2004, Briefings in functional genomics & proteomics.

[44]  W. Dunne,et al.  Evaluation of a Multiplexed Bead Assay for Assessment of Epstein-Barr Virus Immunologic Status , 2004, Journal of Clinical Microbiology.

[45]  Paul Tempst,et al.  A Prototype Antibody Microarray Platform to Monitor Changes in Protein Tyrosine Phosphorylation* , 2004, Molecular & Cellular Proteomics.

[46]  Robert Tibshirani,et al.  Gene expression profiles at diagnosis in de novo childhood AML patients identify FLT3 mutations with good clinical outcomes. , 2004, Blood.

[47]  K. Gardner,et al.  Profiling the expression of mitogen-induced T-cell proteins by using multi-membrane dot-blotting. , 2004, Biochemical and biophysical research communications.

[48]  U. Sundaram,et al.  UPPER GASTROINTESTINAL DISORDERS IN PATIENTS WITH HEPATITIS C: CORRELATION WITH ENDOSCOPY AND PATHOLOGY , 2004 .

[49]  Jennifer L. Harris,et al.  PNA-encoded protease substrate microarrays. , 2004, Chemistry & biology.

[50]  Ryan Okon,et al.  Evaluating sandwich immunoassays in microarray format in terms of the ambient analyte regime. , 2004, Clinical chemistry.

[51]  M. Gerstein,et al.  Genomic analysis of regulatory network dynamics reveals large topological changes , 2004, Nature.

[52]  Eytan Domany,et al.  Functional immunomics: Microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Fred S Apple,et al.  Evaluation of a point-of-care assay for cardiac markers for patients suspected of acute myocardial infarction. , 2004, Clinica chimica acta; international journal of clinical chemistry.

[54]  Jonathan S. Reichner,et al.  Antibodies Immobilized as Arrays to Profile Protein Post-translational Modifications in Mammalian Cells* , 2004, Molecular & Cellular Proteomics.

[55]  R. Jonsson,et al.  Circulating Cytokines in Primary Sjögren's Syndrome Determined by a Multiplex Cytokine Array System , 2004, Scandinavian journal of immunology.

[56]  P. Chan-Hui,et al.  Applications of eTag™ assay platform to systems biology approaches in molecular oncology and toxicology studies , 2004 .

[57]  H. Gaub,et al.  Double chip protein arrays using recombinant single‐chain Fv antibody fragments , 2004, Proteomics.

[58]  David E. Misek,et al.  Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. , 2004, Journal of proteome research.

[59]  Milan Mrksich,et al.  Probing Protein–Carbohydrate Interactions with Microarrays of Synthetic Oligosaccharides , 2004, Chembiochem : a European journal of chemical biology.

[60]  M. W. Mueller,et al.  Microarrayed allergens for IgE profiling. , 2004, Methods.

[61]  Rachel Ostroff,et al.  Photoaptamer arrays applied to multiplexed proteomic analysis , 2004, Proteomics.

[62]  Cui-Yan Tan,et al.  Colorimetric detection of protein microarrays based on nanogold probe coupled with silver enhancement. , 2004, Journal of immunological methods.

[63]  P. Predki Functional protein microarrays: ripe for discovery. , 2004, Current opinion in chemical biology.

[64]  Susan M Varnum,et al.  A protein microarray ELISA for screening biological fluids. , 2004, Methods in molecular biology.

[65]  S. Kingsmore,et al.  Cerebral palsy is characterized by protein mediators in cord serum , 2004, Annals of neurology.

[66]  G. Hu,et al.  Parallel detection of autoantibodies with microarrays in rheumatoid diseases. , 2004, Clinical chemistry.

[67]  A. Aderem,et al.  A systems approach to dissecting immunity and inflammation. , 2004, Seminars in immunology.

[68]  Ruo-Pan Huang,et al.  Enhanced Protein Profiling Arrays with ELISA-Based Amplification for High-Throughput Molecular Changes of Tumor Patients’ Plasma , 2004, Clinical Cancer Research.

[69]  Francesco M Marincola,et al.  Cytokine and chemokine expression profiles of maturing dendritic cells using multiprotein platform arrays. , 2004, Cytokine.

[70]  A. Crisanti,et al.  Serodiagnosis of infectious diseases with antigen microarrays , 2004, Journal of Applied Microbiology.

[71]  R. Laubenbacher,et al.  A computational algebra approach to the reverse engineering of gene regulatory networks. , 2003, Journal of theoretical biology.

[72]  P. Angenendt,et al.  Evaluation of antibodies and microarray coatings as a prerequisite for the generation of optimized antibody microarrays. , 2004, Methods in molecular biology.

[73]  Andrea Crisanti,et al.  Protein arrays for serodiagnosis of disease. , 2004, Methods in molecular biology.

[74]  P. Chan-Hui,et al.  Applications of eTag trade mark assay platform to systems biology approaches in molecular oncology and toxicology studies. , 2004, Clinical immunology.

[75]  Paul Lizardi,et al.  Two-color, rolling-circle amplification on antibody microarrays for sensitive, multiplexed serum-protein measurements , 2004, Genome Biology.

[76]  Stephen Kingsmore,et al.  Optimization of Rolling-Circle Amplified Protein Microarrays for Multiplexed Protein Profiling , 2003, Journal of biomedicine & biotechnology.

[77]  M. Snyder,et al.  Analyzing antibody specificity with whole proteome microarrays , 2003, Nature Biotechnology.

[78]  N V Bovin,et al.  GlycoChip: multiarray for the study of carbohydrate-binding proteins. , 2003, Lab on a chip.

[79]  Barry Schweitzer,et al.  Microarrays to characterize protein interactions on a whole‐proteome scale , 2003, Proteomics.

[80]  Erik J. Erlandson,et al.  Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity , 2003, Proteomics.

[81]  Lawrence Steinman,et al.  Protein arrays for autoantibody profiling and fine‐specificity mapping , 2003, Proteomics.

[82]  M. W. Mueller,et al.  Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen‐specific serum immunoglobulin E , 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[83]  D. Laskowitz,et al.  Early biomarkers of stroke. , 2003, Clinical chemistry.

[84]  Mahesh Uttamchandani,et al.  Combinatorial peptide microarrays for the rapid determination of kinase specificity. , 2003, Bioorganic & medicinal chemistry letters.

[85]  H. Lehrach,et al.  3D protein microarrays: performing multiplex immunoassays on a single chip. , 2003, Analytical chemistry.

[86]  Lawrence Steinman,et al.  Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis , 2003, Nature Biotechnology.

[87]  H. Lehrach,et al.  Next generation of protein microarray support materials: evaluation for protein and antibody microarray applications. , 2003, Journal of chromatography. A.

[88]  John D. Storey,et al.  Statistical significance for genomewide studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[89]  P. Sorger,et al.  Profiling receptor tyrosine kinase activation by using Ab microarrays , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[90]  R. Hargreaves,et al.  Clinical biomarkers in drug discovery and development , 2003, Nature Reviews Drug Discovery.

[91]  Min Zhan,et al.  A data review and re-assessment of ovarian cancer serum proteomic profiling , 2003, BMC Bioinformatics.

[92]  Protein and Nucleic Acid Detection by Rolling Circle Amplification on Gel-based Microarrays , 2003 .

[93]  A. Crisanti,et al.  Protein microarray technology for unraveling the antibody specificity repertoire against microbial proteomes. , 2003, Current opinion in molecular therapeutics (Print).

[94]  A. Mirzabekov,et al.  Hydrogel-based protein microchips: manufacturing, properties, and applications. , 2003, BioTechniques.

[95]  J. Hirabayashi Oligosaccharide microarrays for glycomics. , 2003, Trends in biotechnology.

[96]  T. Kodadek,et al.  Immobilized peptides as high-affinity capture agents for self-associating proteins. , 2003, Chemistry & biology.

[97]  S. Kingsmore,et al.  Multiplexed protein profiling on antibody-based microarrays by rolling circle amplification. , 2003, Current opinion in biotechnology.

[98]  Reinhard Niessner,et al.  Microarrays for the screening of allergen-specific IgE in human serum. , 2003, Analytical chemistry.

[99]  P. Peluso,et al.  Optimizing antibody immobilization strategies for the construction of protein microarrays. , 2003, Analytical biochemistry.

[100]  E. B. Butler,et al.  Antibody microarray profiling of human prostate cancer sera: Antibody screening and identification of potential biomarkers , 2003, Proteomics.

[101]  W. Kuis,et al.  Simultaneous Detection of 15 Human Cytokines in a Single Sample of Stimulated Peripheral Blood Mononuclear Cells , 2003, Clinical Diagnostic Laboratory Immunology.

[102]  John D. Storey,et al.  Statistical Significance for Genome-Wide Studies , 2003 .

[103]  Tuan Vo-Dinh,et al.  Multi-analyte analysis system using an antibody-based biochip , 2003, Analytical and bioanalytical chemistry.

[104]  P. Anderson,et al.  Human Autoimmune Sera as Molecular Probes for the Identification of an Autoantigen Kinase Signaling Pathway , 2002, The Journal of experimental medicine.

[105]  E. Petricoin,et al.  Clinical proteomics: translating benchside promise into bedside reality , 2002, Nature Reviews Drug Discovery.

[106]  M. Lesaicherre,et al.  Antibody-based fluorescence detection of kinase activity on a peptide array. , 2002, Bioorganic & medicinal chemistry letters.

[107]  Martin Sommer,et al.  Array-based multiplexed screening and quantitation of human cytokines and chemokines. , 2002, Journal of proteome research.

[108]  Y. Alguel,et al.  Phage display antibody-based proteomic device using resonance-enhanced detection. , 2002, Journal of nanoscience and nanotechnology.

[109]  B. Nahm,et al.  Quantitative measurement of serum allergen-specific IgE on protein chip , 2002, Experimental & Molecular Medicine.

[110]  Ruo-Pan Huang,et al.  Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology. , 2002, Cancer research.

[111]  Lawrence Steinman,et al.  Autoantibody profiling for the study and treatment of autoimmune disease , 2002, Arthritis research.

[112]  M. A. Bopp,et al.  Zeptosens' protein microarrays: A novel high performance microarray platform for low abundance protein analysis , 2002, Proteomics.

[113]  S. Kingsmore,et al.  Multiplexed protein profiling on microarrays by rolling-circle amplification , 2002, Nature Biotechnology.

[114]  P. Brown,et al.  Autoantigen microarrays for multiplex characterization of autoantibody responses , 2002, Nature Medicine.

[115]  Barry Schweitzer,et al.  Measuring proteins on microarrays. , 2002, Current opinion in biotechnology.

[116]  S. Wiltshire,et al.  Allergen-specific IgE Detection on Microarrays Using Rolling Circle Amplification: Correlation with in Vitro Assays for Serum IgE , 2001 .

[117]  R. Jenison,et al.  Silicon-based biosensors for rapid detection of protein or nucleic acid targets. , 2001, Clinical chemistry.

[118]  R. Huang,et al.  Detection of multiple proteins in an antibody-based protein microarray system. , 2001, Journal of immunological methods.

[119]  M. Hogan,et al.  Simultaneous multianalyte ELISA performed on a microarray platform. , 2001, Clinical chemistry.

[120]  R. Huang,et al.  Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. , 2001, Analytical biochemistry.

[121]  R. Tibshirani,et al.  Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[122]  S. Nock,et al.  Monolayers of derivatized poly(L-lysine)-grafted poly(ethylene glycol) on metal oxides as a class of biomolecular interfaces. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[123]  Susan E. Sharp,et al.  Evaluation of the Triage Micro Parasite Panel for Detection of Giardia lamblia, Entamoeba histolytica/Entamoeba dispar, and Cryptosporidium parvum in Patient Stool Specimens , 2001, Journal of Clinical Microbiology.

[124]  P. Brown,et al.  Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions , 2001, Genome Biology.

[125]  S O'Malley,et al.  Detection of multiple allergen-specific IgEs on microarrays by immunoassay with rolling circle amplification. , 2000, Clinical chemistry.

[126]  M. Gerstein,et al.  Analysis of yeast protein kinases using protein chips , 2000, Nature Genetics.

[127]  S. Schreiber,et al.  Printing proteins as microarrays for high-throughput function determination. , 2000, Science.

[128]  Lucy J. Holt,et al.  By-passing selection: direct screening for antibody-antigen interactions using protein arrays. , 2000, Nucleic acids research.

[129]  S. Kingsmore,et al.  Immunoassays with rolling circle DNA amplification: a versatile platform for ultrasensitive antigen detection. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[130]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[131]  H. Lehrach,et al.  Protein arrays for gene expression and molecular interaction screening. , 2000, Current opinion in microbiology.

[132]  L. G. Mendoza,et al.  High-throughput microarray-based enzyme-linked immunosorbent assay (ELISA). , 1999, BioTechniques.

[133]  L. P. Zhao,et al.  On the assessment of statistical significance in disease-gene discovery. , 1999, American journal of human genetics.

[134]  J. Weller,et al.  A new approach to the problem of multiple comparisons in the genetic dissection of complex traits. , 1998, Genetics.

[135]  R. Ekins,et al.  Ligand assays: from electrophoresis to miniaturized microarrays. , 1998, Clinical chemistry.

[136]  P. Lizardi,et al.  Mutation detection and single-molecule counting using isothermal rolling-circle amplification , 1998, Nature Genetics.

[137]  R J Fulton,et al.  Advanced multiplexed analysis with the FlowMetrix system. , 1997, Clinical chemistry.

[138]  A. Podtelejnikov,et al.  Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[139]  A. Shenhav,et al.  Simultaneous detection of seven drugs of abuse by the Triage panel for drugs of abuse. , 1992, Clinical chemistry.

[140]  F W Chu,et al.  Multianalyte microspot immunoassay--microanalytical "compact disk" of the future. , 1991, Clinical chemistry.

[141]  Lysov YuP,et al.  A method for DNA sequencing by hybridization with oligonucleotide matrix. , 1991, DNA sequence : the journal of DNA sequencing and mapping.

[142]  H. Imura,et al.  Increased human brain natriuretic peptide in congestive heart failure. , 1990, The New England journal of medicine.

[143]  A. Remppis,et al.  Enzyme linked immuno assay of cardiac troponin T for the detection of acute myocardial infarction in patients. , 1989, Journal of molecular and cellular cardiology.

[144]  M P Busch,et al.  Early detection of antibodies against rDNA-produced HIV proteins with a flow cytometric assay. , 1989, Blood.

[145]  R. Ekins,et al.  Multi-analyte immunoassay. , 1989, Journal of pharmaceutical and biomedical analysis.