Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage

[1]  Adnan Tufail,et al.  Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration , 2018, Nature Biotechnology.

[2]  D. Clegg,et al.  ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell–Derived Retinal Pigmented Epithelium , 2016, Translational vision science & technology.

[3]  Qin Wan,et al.  In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications , 2016, Stem cells translational medicine.

[4]  J. Hyttinen,et al.  Semi-automatic Method for Ca2+ Imaging Data Analysis of Maturing Human Embryonic Stem Cells-Derived Retinal Pigment Epithelium , 2016, Annals of Biomedical Engineering.

[5]  SorkioAnni,et al.  Surface modified biodegradable electrospun membranes as a carrier for human embryonic stem cell derived retinal pigment epithelial cells , 2015 .

[6]  P. Rosenfeld,et al.  Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies , 2015, The Lancet.

[7]  B. Meenan,et al.  Surface Modified Biodegradable Electrospun Membranes as a Carrier for Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. , 2015, Tissue engineering. Part A.

[8]  M. Kellomäki,et al.  Ormocomp-modified glass increases collagen binding and promotes the adherence and maturation of human embryonic stem cell-derived retinal pigment epithelial cells. , 2014, Langmuir : the ACS journal of surfaces and colloids.

[9]  H. Uusitalo,et al.  Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. , 2014, Tissue engineering. Part A.

[10]  E. Capowski,et al.  Functional analysis of serially expanded human iPS cell-derived RPE cultures. , 2013, Investigative ophthalmology & visual science.

[11]  Lyndon da Cruz,et al.  Development of human embryonic stem cell therapies for age-related macular degeneration , 2013, Trends in Neurosciences.

[12]  A. Salminen,et al.  Cellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization. , 2013, The international journal of biochemistry & cell biology.

[13]  J. Cordeiro,et al.  The role of transcription-independent damage signals in the initiation of epithelial wound healing , 2013, Nature Reviews Molecular Cell Biology.

[14]  J. Hyttinen,et al.  Intercellular Ca(2+) wave propagation in human retinal pigment epithelium cells induced by mechanical stimulation. , 2012, Experimental eye research.

[15]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[16]  S. Schwartz,et al.  Embryonic stem cell trials for macular degeneration: a preliminary report , 2012, The Lancet.

[17]  G. Guerra,et al.  The Mechanism of Injury-Induced Intracellular Calcium Concentration Oscillations in the Endothelium of Excised Rat Aorta , 2011, Journal of Vascular Research.

[18]  H. Uusitalo,et al.  Toward the defined and xeno-free differentiation of functional human pluripotent stem cell–derived retinal pigment epithelial cells , 2011, Molecular vision.

[19]  D. Hicks,et al.  The retinal pigment epithelium in health and disease. , 2010, Current molecular medicine.

[20]  Shannon M. Gallagher-Colombo,et al.  Modulation of MCT3 expression during wound healing of the retinal pigment epithelium. , 2010, Investigative ophthalmology & visual science.

[21]  H. Kaplan,et al.  Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact. , 2010, Investigative ophthalmology & visual science.

[22]  H. Skottman.  Derivation and characterization of three new human embryonic stem cell lines in Finland , 2010, In Vitro Cellular & Developmental Biology - Animal.

[23]  Y. Hui,et al.  Modulation of Migration and Ca2+ Signaling in Retinal Pigment Epithelium Cells by Recombinant Human CTGF , 2009, Current eye research.

[24]  J. Southgate,et al.  Calcium signalling in wound-responsive normal human urothelial cell monolayers. , 2008, Cell calcium.

[25]  Thomas D. Schmittgen,et al.  Analyzing real-time PCR data by the comparative CT method , 2008, Nature Protocols.

[26]  B. Stanzel,et al.  Transplantation of the RPE in AMD , 2007, Progress in Retinal and Eye Research.

[27]  O. Strauß,et al.  Ion channels in the RPE , 2007, Progress in Retinal and Eye Research.

[28]  Ashok Kumar,et al.  Wound-induced ATP release and EGF receptor activation in epithelial cells , 2007, Journal of Cell Science.

[29]  Olaf Strauss,et al.  The retinal pigment epithelium in visual function. , 2005, Physiological reviews.

[30]  Peter Mobbs,et al.  ATP Released via Gap Junction Hemichannels from the Pigment Epithelium Regulates Neural Retinal Progenitor Proliferation , 2005, Neuron.

[31]  Rizwan U. Farooqui,et al.  Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement , 2005, Journal of Cell Science.

[32]  P. Mobbs,et al.  Ca2+ signalling and gap junction coupling within and between pigment epithelium and neural retina in the developing chick , 2004, The European journal of neuroscience.

[33]  Miki Ebisuya,et al.  ERK Activation Propagates in Epithelial Cell Sheets and Regulates Their Migration during Wound Healing , 2004, Current Biology.

[34]  N. Rao,et al.  Scanning and transmission electron microscopic findings during RPE wound healing in vivo , 2004, International Ophthalmology.

[35]  M. Zarbin,et al.  Retinal pigment epithelium wound healing in human Bruch's membrane explants. , 2003, Investigative ophthalmology & visual science.

[36]  K. Shiraki,et al.  Hepatocyte growth factor stimulates proliferation and migration during wound healing of retinal pigment epithelial cells in vitro. , 2003, Japanese journal of ophthalmology.

[37]  Kenneth M. Yamada,et al.  Transmembrane crosstalk between the extracellular matrix and the cytoskeleton , 2001, Nature Reviews Molecular Cell Biology.

[38]  Paul Martin,et al.  Mechanisms of epithelial fusion and repair , 2001, Nature Cell Biology.

[39]  B. Geiger,et al.  Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk. , 2001, Nature reviews. Molecular cell biology.

[40]  Paul Martin,et al.  Conserved mechanisms of repair: from damaged single cells to wounds in multicellular tissues , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[41]  B. Himpens,et al.  Properties of intra- and intercellular Ca(2+)-wave propagation elicited by mechanical stimulation in cultured RPE cells. , 1999, Cell calcium.

[42]  B. Himpens,et al.  Intra‐ and intercellular Ca2+ signaling in retinal pigment epithelial cells during mechanical stimulation , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[43]  G. Unger,et al.  A wound-induced [Ca2+]i increase and its transcriptional activation of immediate early genes is important in the regulation of motility. , 1999, Experimental cell research.

[44]  P. Sammak,et al.  Co‐ordination between localized wound‐induced Ca2+ signals and pre‐wound serum signals is required for proliferation after mechanical injury , 1998, Cell proliferation.

[45]  D. Hinton,et al.  Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. , 1996, Investigative ophthalmology & visual science.

[46]  V. Kalnins,et al.  Inhibition of retinal pigment epithelial cell migration and proliferation with monoclonal antibodies against the beta 1 integrin subunit during wound healing in organ culture. , 1993, Investigative ophthalmology & visual science.