Automated Segmentation and Reconstruction of the Subthalamic Nucleus in Parkinson's Disease Patients

In the treatment of Parkinson's disease for deep brain stimulation (DBS), the subthalamic nucleus (STN) is the most important target on a specific brain nucleus. Although procedural details are well established, targeting STN remains problematic because of its variable location and relatively small size.

[1]  Jianping Fan,et al.  Seeded region growing: an extensive and comparative study , 2005, Pattern Recognit. Lett..

[2]  Angel Domingo Sappa,et al.  Implicit B-spline fitting using the 3L algorithm , 2011, 2011 18th IEEE International Conference on Image Processing.

[3]  Tony F. Chan,et al.  Active contours without edges , 2001, IEEE Trans. Image Process..

[4]  M. Proescholdt,et al.  The influence of intraoperative microelectrode recordings and clinical testing on the location of final stimulation sites in deep brain stimulation for Parkinson’s disease , 2013, Acta Neurochirurgica.

[5]  E. Laasonen,et al.  Accidental introduction of contrast medium into the cervical spinal cord , 2004, Neuroradiology.

[6]  Erich O. Richter,et al.  Determining the position and size of the subthalamic nucleus based on magnetic resonance imaging results in patients with advanced Parkinson disease. , 2004, Journal of neurosurgery.

[7]  M. Jahanshahi,et al.  Long-term outcome of subthalamic nucleus deep brain stimulation for Parkinson's disease using an MRI-guided and MRI-verified approach , 2014, Journal of Neurology, Neurosurgery & Psychiatry.

[8]  Y. Ben-Shlomo,et al.  Stimulation of the caudal zona incerta is superior to stimulation of the subthalamic nucleus in improving contralateral parkinsonism. , 2006, Brain : a journal of neurology.

[9]  Aviva Abosch,et al.  Localization of clinically effective stimulating electrodes in the human subthalamic nucleus on magnetic resonance imaging. , 2002, Journal of neurosurgery.

[10]  Parag G. Patil,et al.  The anatomical and electrophysiological subthalamic nucleus visualized by 3-T magnetic resonance imaging. , 2012, Neurosurgery.

[11]  Chunming Li,et al.  Distance Regularized Level Set Evolution and Its Application to Image Segmentation , 2010, IEEE Transactions on Image Processing.

[12]  C B Maks,et al.  Deep brain stimulation activation volumes and their association with neurophysiological mapping and therapeutic outcomes , 2008, Journal of Neurology, Neurosurgery, and Psychiatry.

[13]  Philip A. Starr,et al.  Placement of Deep Brain Stimulators into the Subthalamic Nucleus or Globus pallidus internus: Technical Approach , 2003, Stereotactic and Functional Neurosurgery.

[14]  M. Zanca,et al.  Magnetic resonance imaging stereotactic target localization for deep brain stimulation in dystonic children. , 2000, Journal of neurosurgery.

[15]  Alfred M. Bruckstein,et al.  Finding Shortest Paths on Surfaces Using Level Sets Propagation , 1995, IEEE Trans. Pattern Anal. Mach. Intell..

[16]  K V Slavin,et al.  Direct visualization of the human subthalamic nucleus with 3T MR imaging. , 2006, AJNR. American journal of neuroradiology.

[17]  Yi-li Fu,et al.  Stereotactic localization and visualization of the subthalamic nucleus. , 2009, Chinese medical journal.

[18]  M. Merello,et al.  Deep Brain Stimulation of the Subthalamic Nucleus for the Treatment of Parkinson's Disease , 2008 .

[19]  Shabbar F. Danish,et al.  Functional localization and visualization of the subthalamic nucleus from microelectrode recordings acquired during DBS surgery with unsupervised machine learning , 2009, Journal of neural engineering.

[20]  M. Mallar Chakravarty,et al.  Atlas-Based Segmentation of the Subthalamic Nucleus, Red Nucleus, and Substantia Nigra for Deep Brain Stimulation by Incorporating Multiple MRI Contrasts , 2012, IPCAI.

[21]  Jasjit S. Suri,et al.  Handbook of Biomedical Image Analysis , 2005 .

[22]  Bram Platel,et al.  Magnetic resonance imaging techniques for visualization of the subthalamic nucleus. , 2011, Journal of neurosurgery.

[23]  P. Starr,et al.  Implantation of deep brain stimulators into the subthalamic nucleus: technical approach and magnetic resonance imaging-verified lead locations. , 2002, Journal of neurosurgery.

[24]  Nicolas Guizard,et al.  Investigation of morphometric variability of subthalamic nucleus, red nucleus, and substantia nigra in advanced Parkinson's disease patients using automatic segmentation and PCA‐based analysis , 2014, Human brain mapping.

[25]  Francesco Cardinale,et al.  Stimulus‐evoked potentials contribute to map the epileptogenic zone during stereo‐EEG presurgical monitoring , 2014, Human brain mapping.

[26]  A. Lozano,et al.  Direct visualization of deep brain stimulation targets in Parkinson disease with the use of 7-tesla magnetic resonance imaging. , 2010, Journal of neurosurgery.

[27]  L Lopiano,et al.  Deep brain stimulation of the subthalamic nucleus: anatomical, neurophysiological, and outcome correlations with the effects of stimulation , 2002, Journal of neurology, neurosurgery, and psychiatry.

[28]  Guillermo Sapiro,et al.  Geodesic Active Contours , 1995, International Journal of Computer Vision.

[29]  E. Eskandar,et al.  Stereotactic pallidotomy performed without using microelectrode guidance in patients with Parkinson's disease: surgical technique and 2-year results. , 2000, Journal of neurosurgery.

[30]  Seth Love,et al.  MRI-Directed Subthalamic Nucleus Surgery for Parkinson’s Disease , 2003, Stereotactic and Functional Neurosurgery.

[31]  Allen R. Tannenbaum,et al.  Localizing Region-Based Active Contours , 2008, IEEE Transactions on Image Processing.

[32]  M. Jahanshahi,et al.  MRI-guided STN DBS in Parkinson's disease without microelectrode recording: efficacy and safety , 2010, Journal of Neurology, Neurosurgery & Psychiatry.