MicroRNA-20a participates in the aerobic exercise-based prevention of coronary artery disease by targeting PTEN.

[1]  Q. Wan,et al.  MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway , 2017, Scientific Reports.

[2]  Jun Yu,et al.  The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis , 2017, International journal of molecular sciences.

[3]  O. Barbier,et al.  Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay , 2017, Hepatology.

[4]  Xi-Long Zheng,et al.  Myocyte-specific enhancer factor 2C: a novel target gene of miR-214-3p in suppressing angiotensin II-induced cardiomyocyte hypertrophy , 2016, Scientific Reports.

[5]  G. A. Wilkinson,et al.  Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway , 2015, PloS one.

[6]  C. Vrints,et al.  Effects of aerobic interval training and continuous training on cellular markers of endothelial integrity in coronary artery disease: a SAINTEX-CAD substudy. , 2015, American journal of physiology. Heart and circulatory physiology.

[7]  A. Russell,et al.  Comparative analysis of microRNA expression in mouse and human brown adipose tissue , 2015, BMC Genomics.

[8]  Longhua Chen,et al.  MiR-20a Induces Cell Radioresistance by Activating the PTEN/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma. , 2015, International journal of radiation oncology, biology, physics.

[9]  Wei Jiang,et al.  Integrated systems approach identifies risk regulatory pathways and key regulators in coronary artery disease , 2015, Journal of Molecular Medicine.

[10]  Li Zhang,et al.  The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer , 2015, Oncotarget.

[11]  Tin-Lap Lee,et al.  Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway. , 2015, Biomaterials.

[12]  A. K. Poyraz,et al.  The relationship between coronary artery disease and pericoronary epicardial adipose tissue thickness , 2015, The Journal of international medical research.

[13]  M. Trenell,et al.  Physical Activity in the Management of Patients with Coronary Artery Disease: A Review , 2015, Cardiology in review.

[14]  P. Pacaud,et al.  Involvement of Rho GTPases and their regulators in the pathogenesis of hypertension , 2014, Small GTPases.

[15]  C. Heaps,et al.  Exercise training enhances multiple mechanisms of relaxation in coronary arteries from ischemic hearts. , 2013, American journal of physiology. Heart and circulatory physiology.

[16]  Yan-na Cheng,et al.  Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells , 2013, Journal of cellular biochemistry.

[17]  M. Giacca,et al.  VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond , 2012, Gene Therapy.

[18]  A. Tijsen,et al.  Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? , 2012, Circulation research.

[19]  Stefanie Dimmeler,et al.  Circulating microRNAs: biomarkers or mediators of cardiovascular diseases? , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[20]  Thomas J. Wang,et al.  Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training , 2011, The Journal of physiology.

[21]  T. Matsui,et al.  Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failure. , 2011, Current pharmaceutical design.

[22]  Stefanie Dimmeler,et al.  Circulating MicroRNAs in Patients With Coronary Artery Disease , 2010, Circulation research.

[23]  M. Keane,et al.  Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease. , 2010, American journal of physiology. Heart and circulatory physiology.

[24]  H. Horita,et al.  Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation. , 2010, Cardiovascular research.

[25]  Guohua Gong,et al.  Rutin inhibits hydrogen peroxide-induced apoptosis through regulating reactive oxygen species mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells. , 2010, European journal of pharmacology.

[26]  L. Mazzolai,et al.  Long-term exercise stabilizes atherosclerotic plaque in ApoE knockout mice. , 2009, Medicine and science in sports and exercise.

[27]  M. Satoh,et al.  Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease , 2009, European journal of clinical investigation.

[28]  P. Wołkow,et al.  The effect of montelukast on atherogenesis in apoE/LDLR-double knockout mice. , 2008, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[29]  X. Zhang,et al.  Coronary heart disease in China , 2008, Heart.

[30]  C. Franceschi,et al.  2-deoxy-d-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. , 2008, Free radical biology & medicine.

[31]  D. Agrawal,et al.  Regulation of cell cycle entry by PTEN in smooth muscle cell proliferation of human coronary artery bypass conduits , 2008, Journal of cellular and molecular medicine.

[32]  M. Birnbaum,et al.  Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. , 2007, Cell metabolism.

[33]  P. Schnohr,et al.  Long-term physical activity in leisure time and mortality from coronary heart disease, stroke, respiratory diseases, and cancer. The Copenhagen City Heart Study , 2006, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[34]  J. Coselli,et al.  Up-regulation of PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome Ten) Mediates p38 MAPK Stress Signal-induced Inhibition of Insulin Signaling , 2006, Journal of Biological Chemistry.

[35]  T. Kodama,et al.  A simple method of isolating mouse aortic endothelial cells. , 2005, Journal of atherosclerosis and thrombosis.

[36]  N. de Las Heras,et al.  Role of endothelin-1 and thromboxane A2 in renal vasoconstriction induced by angiotensin II in diabetes and hypertension. , 2002, Kidney international. Supplement.

[37]  Lewis C Cantley,et al.  The phosphoinositide 3-kinase pathway. , 2002, Science.

[38]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[39]  R S Paffenbarger,et al.  Physical Activity and Coronary Heart Disease in Men: The Harvard Alumni Health Study , 2000, Circulation.

[40]  P. Vogt,et al.  Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[41]  P. Thorén,et al.  Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[42]  N. Tamura,et al.  Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis. , 1998, Circulation.

[43]  S. Bunting,et al.  Vascular endothelial growth factor, a specific regulator of angiogenesis , 1996, Current opinion in nephrology and hypertension.

[44]  F. Barillà,et al.  Dynamic Exercise Induces Elevation of Plasma Levels of Endothelin-1 in Patients with Coronary Artery Disease , 1995, Angiology.

[45]  J. Eidt,et al.  Treadmill exercise promotes cyclic alterations in coronary blood flow in dogs with coronary artery stenoses and endothelial injury. , 1989, The Journal of clinical investigation.

[46]  Anatoly I Grigoriev,et al.  Exercise immunology meets MiRNAs. , 2014, Exercise immunology review.

[47]  R. Hambrecht,et al.  Exercise and the coronary circulation-alterations and adaptations in coronary artery disease. , 2006, Progress in cardiovascular diseases.

[48]  Wu Kk.  Prostacyclin and nitric oxide-related gene transfer in preventing arterial thrombosis and restenosis. , 1997 .