Valve repair to avoid prosthetic valve pathology: Mid-term results in mitral valve repair.

Background In this study, we aimed to present our results of mitral valve repair. Methods Between January 2007 and November 2016, a total of 128 patients (72 males, 56 females; mean age 51.8±17.2 years; range 16 to 84 years) who underwent mitral valve repair in our heart center were retrospectively analyzed. There were mitral regurgitation in 86.7% (n=111), mitral stenosis in 7.8% (n=10), and mixed type valve disease in 5.5% of the patients (n=7). Mitral ring annuloplasty was performed in 80.5% (n=103), implantation of the artificial chordae in 36.7% (n=47), open mitral commissurotomy in 13.3% (n=17), and Alfieri procedure in 6.3% (n=8) of the patients. Sixty-two patients (48.8%) underwent isolated mitral valve repair, while concomitant surgical procedures were performed in the remaining patients. Postoperative mean follow-up was 52 months. Results Early (30-day) mortality was observed in seven patients due to low cardiac output. There was no mid-term mortality. During follow-up, various degree of mitral regurgitation was detected in 4 patients (3.6%), regurgitation was severe in two of them and these two require reoperation with the replacement of the valve. Patients with a myxomatous valve pathology who underwent isolated valve repair most benefited from valve repair. Patients with isolated mitral stenosis were the most successful group among the patients with a rheumatic etiology. Postoperative echocardiography showed a significant decrease in the left atrial diameter and pulmonary artery systolic pressures (p<0.01). Conclusion Mitral valve repair can be applied as an effective and safe treatment method in patients in whom the mitral valve anatomy is sufficient for repair. We suggest that each patient with mitral valve pathology should be evaluated in terms of reparability.

[1]  Christos G Mihos,et al.  The role of papillary muscle approximation in mitral valve repair for the treatment of secondary mitral regurgitation. , 2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  H. Jensen Surgical treatment of functional ischemic mitral regurgitation. , 2015, Danish medical journal.

[3]  M. Moscarelli,et al.  Surgical management of moderate ischemic mitral valve regurgitation: Where do we stand? , 2014, World journal of cardiology.

[4]  M. Güden,et al.  Clinical outcomes of mitral valve repair in mitral regurgitation: a prospective analysis of 100 consecutive patients. , 2011, Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology.

[5]  Qiang Zhao,et al.  Systematic evaluation of the flexible and rigid annuloplasty ring after mitral valve repair for mitral regurgitation. , 2011, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[6]  A. Şaşmazel,et al.  Results of mitral valve repair in rheumatic mitral lesions. , 2010, The heart surgery forum.

[7]  M. Enriquez-Sarano,et al.  Recovery of left ventricular function after surgical correction of mitral regurgitation caused by leaflet prolapse. , 2009, The Journal of thoracic and cardiovascular surgery.

[8]  Robert J Anderson,et al.  Meta-analysis of clinical outcomes following surgical mitral valve repair or replacement. , 2007, European Journal of Cardio-Thoracic Surgery.

[9]  P. Lancellotti,et al.  [Ischemic mitral regurgitation]. , 2007, Archives des maladies du coeur et des vaisseaux.

[10]  M. Enriquez-Sarano,et al.  Quantitative determinants of the outcome of asymptomatic mitral regurgitation. , 2005, The New England journal of medicine.

[11]  W. Wells,et al.  Neochordal repair of the posterior mitral leaflet. , 2004, Journal of Thoracic and Cardiovascular Surgery.

[12]  A. Sosnowski,et al.  Mitral valve relpair and revascularization for ischemic mitral regurgitation: predictors of operative mortality and survival. , 2002, The Journal of heart valve disease.

[13]  A. Gillinov,et al.  Mitral valve repair for degenerative disease. , 2002, The Journal of heart valve disease.

[14]  G Chatellier,et al.  Very Long-Term Results (More Than 20 Years) of Valve Repair With Carpentier’s Techniques in Nonrheumatic Mitral Valve Insufficiency , 2001, Circulation.

[15]  M. Campana,et al.  Biological versus prosthetic ring in mitral-valve repair: enhancement of mitral annulus dynamics and left-ventricular function with pericardial annuloplasty at long term. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[16]  N G Smedira,et al.  Durability of mitral valve repair for degenerative disease. , 1998, The Journal of thoracic and cardiovascular surgery.

[17]  L. Cohn,et al.  The effect of pathophysiology on the surgical treatment of ischemic mitral regurgitation: operative and late risks of repair versus replacement. , 1995, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[18]  D. C. Miller,et al.  Mitral valve repair versus replacement. , 1991, Cardiology clinics.

[19]  M. Enriquez-Sarano,et al.  Chapter 76 – Mitral Regurgitation , 2009 .