MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia

[1]  L. Hudson,et al.  Sustained Activation of the Mitogen-activated Protein Kinase Pathway , 1999, The Journal of Biological Chemistry.

[2]  E. Kandel,et al.  Mutation in the Phosphorylation Sites of MAP Kinase Blocks Learning-Related Internalization of apCAM in Aplysia Sensory Neurons , 1997, Neuron.

[3]  H. Yao,et al.  cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway , 1997, Cell.

[4]  E. Kandel,et al.  Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory , 1997, Cell.

[5]  J. Byrne,et al.  Role of Transforming Growth Factor-β in Long-Term Synaptic Facilitation in Aplysia , 1997, Science.

[6]  U. Frey,et al.  Synaptic tagging and long-term potentiation , 1997, Nature.

[7]  L. Pannell,et al.  Carboxypeptidase E Is a Regulated Secretory Pathway Sorting Receptor: Genetic Obliteration Leads to Endocrine Disorders in Cpefat Mice , 1997, Cell.

[8]  J. Ferrell Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. , 1996, Trends in biochemical sciences.

[9]  E. Kandel,et al.  Toward a molecular definition of long-term memory storage. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[10]  J. David Sweatt,et al.  Activation of p42 Mitogen-activated Protein Kinase in Hippocampal Long Term Potentiation* , 1996, The Journal of Biological Chemistry.

[11]  C. Goodman,et al.  Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. III. CREB Is Necessary for Presynaptic Functional Plasticity , 1996, Neuron.

[12]  Richard D Fetter,et al.  Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. II. Fasciclin II Controls Presynaptic Structural Plasticity , 1996, Neuron.

[13]  Michael E. Greenberg,et al.  Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase , 1996, Science.

[14]  F. Gage,et al.  The Signal-Dependent Coactivator CBP Is a Nuclear Target for pp90RSK , 1996, Cell.

[15]  D. Muller,et al.  Induction of long-term potentiation is associated with major ultrastructural changes of activated synapses. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[16]  W. Sossin Mechanisms for the generation of synapse specificity in long-term memory: the implications of a requirement for transcription. , 1996, Trends in Neurosciences.

[17]  F. Morrell,et al.  Synapse restructuring associated with the maintenance phase of hippocampal long‐term potentiation , 1996, The Journal of comparative neurology.

[18]  T. Carew,et al.  Molecular Enhancement of Memory Formation , 1996, Neuron.

[19]  Mary Chen,et al.  Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change , 1995, Cell.

[20]  Philip R. Cohen,et al.  PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo(*) , 1995, The Journal of Biological Chemistry.

[21]  F. Edwards,et al.  Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation. , 1995, Physiological reviews.

[22]  M. Loda,et al.  Cyclic Adenosine Monophosphate Can Convert Epidermal Growth Factor into a Differentiating Factor in Neuronal Cells (*) , 1995, The Journal of Biological Chemistry.

[23]  E. Krebs,et al.  Protein Serine/Threonine Kinases of the MAPK Cascade , 1995, Annals of the New York Academy of Sciences.

[24]  A. Bridges,et al.  A synthetic inhibitor of the mitogen-activated protein kinase cascade. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[25]  H. Bourne,et al.  Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1. , 1995, Molecular biology of the cell.

[26]  J. Pouysségur,et al.  Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts. , 1995, Oncogene.

[27]  Tim Tully,et al.  Dissection of memory formation: from behavioral pharmacology to molecular genetics , 1995, Trends in Neurosciences.

[28]  C. Marshall,et al.  Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation , 1995, Cell.

[29]  N. Sonenberg,et al.  PHAS-I as a link between mitogen-activated protein kinase and translation initiation. , 1994, Science.

[30]  E. Kandel,et al.  cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase , 1994, Cell.

[31]  G. Johnson,et al.  B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP , 1994, Molecular and cellular biology.

[32]  R. Nicoll,et al.  Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP. , 1994, Science.

[33]  E. Kandel,et al.  Temporal and spatial regulation of the expression of BAD2, a MAP kinase phosphatase, during seizure, kindling, and long-term potentiation. , 1994, Learning & memory.

[34]  T. Bliss,et al.  Spatial and temporal changes in signal transduction pathways during LTP , 1994, Neuron.

[35]  E. Kandel,et al.  Requirement of a critical period of transcription for induction of a late phase of LTP. , 1994, Science.

[36]  K. Blumer,et al.  Diversity in function and regulation of MAP kinase pathways. , 1994, Trends in biochemical sciences.

[37]  E. Kandel,et al.  Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization. , 1994, Learning & memory.

[38]  E. Kandel,et al.  C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia , 1994, Cell.

[39]  H. Bourne,et al.  cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. , 1994, The Journal of biological chemistry.

[40]  E. Van Obberghen,et al.  Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. , 1994, The Journal of biological chemistry.

[41]  S. Cook,et al.  Inhibition by cAMP of Ras-dependent activation of Raf. , 1993, Science.

[42]  E. Krebs,et al.  Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[43]  J. Lawrence,et al.  Increasing cAMP attenuates activation of mitogen-activated protein kinase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[44]  R. Davis,et al.  Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus , 1993, The Journal of cell biology.

[45]  E. Krebs,et al.  Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells. , 1993, The Journal of biological chemistry.

[46]  Jonathan A. Cooper,et al.  p42 mitogen-activated protein kinase in brain: Prominent localization in neuronal cell bodies and dendrites , 1993, Neuroscience.

[47]  E. Kandel,et al.  Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. , 1993, Science.

[48]  E R Kandel,et al.  Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons. , 1993, Science.

[49]  Kristen M. Harris,et al.  Quantal analysis and synaptic anatomy — integrating two views of hippocampal plasticity , 1993, Trends in Neurosciences.

[50]  S. Akira,et al.  Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[51]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[52]  P. Cohen,et al.  Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. , 1992, The Biochemical journal.

[53]  E R Kandel,et al.  Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia. , 1992, Science.

[54]  E. Kandel,et al.  Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia. , 1992, Science.

[55]  R. Davis,et al.  Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases. , 1991, The Journal of biological chemistry.

[56]  M E Greenberg,et al.  Stimulation of protein tyrosine phosphorylation by NMDA receptor activation , 1991, Science.

[57]  S. Pelech,et al.  Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase. , 1991, The Journal of biological chemistry.

[58]  E. Kandel,et al.  Target-dependent structural changes accompanying long-term synaptic facilitation in Aplysia neurons. , 1990, Science.

[59]  Eric R. Kandel,et al.  Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation , 1990, Nature.

[60]  E R Kandel,et al.  Inhibitor of protein synthesis blocks long-term behavioral sensitization in the isolated gill-withdrawal reflex of Aplysia. , 1989, Journal of neurobiology.

[61]  C. H. Bailey,et al.  Long-term sensitization in Aplysia increases the number of presynaptic contacts onto the identified gill motor neuron L7. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[62]  E. Kandel,et al.  cAMP evokes long-term facilitation in Aplysia sensory neurons that requires new protein synthesis. , 1988, Science.

[63]  E. Kandel,et al.  Long-term facilitation in Aplysia involves increase in transmitter release. , 1988, Science.

[64]  E R Kandel,et al.  A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. , 1986, Science.

[65]  S. Schacher,et al.  Synaptic plasticity in vitro: cell culture of identified Aplysia neurons mediating short-term habituation and sensitization , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[66]  Philip Goelet,et al.  The long and the short of long–term memory—a molecular framework , 1986, Nature.

[67]  L. Squire,et al.  Protein synthesis and memory: a review. , 1984, Psychological bulletin.

[68]  K. Hagino-Yamagishi,et al.  [Oncogene]. , 2019, Gan to kagaku ryoho. Cancer & chemotherapy.

[69]  C. H. Bailey,et al.  Morphological basis of long-term habituation and sensitization in Aplysia. , 1983, Science.