A Review of Coronary Artery Disease Research in Malaysia.

Coronary artery disease is the major cause of mortality and morbidity in Malaysia and worldwide. This paper reviews all research and publications on coronary artery disease in Malaysia published between 2000-2015. 508 papers were identified of which 146 papers were selected and reviewed on the basis of their relevance. The epidemiology, etiology, risk factors, prevention, assessment, treatment, and outcomes of coronary artery disease in the country are reviewed and summarized. The clinical relevance of the studies done in the country are discussed along with recommendations for future research.

[1]  S. Thambiah,et al.  UTILITY OF COPEPTIN IN ACUTE MYOCARDIAL INFARCTION , 2015 .

[2]  S. Muniandy,et al.  Role of Nε-(Carboxymethyl)Lysine in the Development of Ischemic Heart Disease in Type 2 Diabetes Mellitus , 2007, Journal of clinical biochemistry and nutrition.

[3]  Yaman Walid Kassab,et al.  Patients’ adherence to secondary prevention pharmacotherapy after acute coronary syndromes , 2013, International Journal of Clinical Pharmacy.

[4]  R. Yusof,et al.  Ala519Thr Mutation in Exon 11 of LDL Receptor Gene in Members of a Malaysian Family with Hypercholesterolaemia , 2003 .

[5]  Y. Lee,et al.  Thrombolytic failure with streptokinase in acute myocardial infarction using electrocardiogram criteria. , 2008, Singapore medical journal.

[6]  S. Azarisman,et al.  Myocardial infarction induced by appetite suppressants in Malaysia. , 2007, The New England journal of medicine.

[7]  H. S. Eng,et al.  Anxiety and Depression among Patients Before and After Percutaneous Coronary Intervention (PCI) at National Heart Institute (NHI) , 2007 .

[8]  Liancheng Zhao,et al.  Current status of cholesterol goal attainment after statin therapy among patients with hypercholesterolemia in Asian countries and region: the Return on Expenditure Achieved for Lipid Therapy in Asia (REALITY-Asia) study , 2008, Current medical research and opinion.

[9]  Sherina Mohd Sidik,et al.  Prevalence of depression with chronic illness among the elderly in a rural community in Malaysia , 2003 .

[10]  Alan Yean Yip Fong,et al.  An Asian Validation of the TIMI Risk Score for ST-Segment Elevation Myocardial Infarction , 2012, PloS one.

[11]  K. Yew Further elucidation on "Hybrid ABSORB bioresorbable vascular scaffold and drug eluting stent or hybrid BVS-DES percutaneous coronary intervention: Method and rationale for hybrid overlapping PCI". , 2015, International journal of cardiology.

[12]  K. Yew The role of fractional flow reserve in pre-operative coronary angiography in redefining functional syntax score and cardiac risk in multivessel coronary artery disease. , 2014, International journal of cardiology.

[13]  M. Bots,et al.  Impact of cardiac care variation on ST-elevation myocardial infarction outcomes in Malaysia. , 2013, The American journal of cardiology.

[14]  W. Ahmad,et al.  Malaysia-ACute CORonary syndromes Descriptive study (ACCORD): evaluation of compliance with existing guidelines in patients with acute coronary syndrome. , 2011, Singapore medical journal.

[15]  B. Khalid,et al.  New coronary risk factors: is there a difference between diabetic patients with microalbuminuria compared to those without microalbuminuria? , 2002, The Medical journal of Malaysia.

[16]  W. W. Wan Ahmad,et al.  Failure to improve door-to-needle time by switching to emergency physician-initiated thrombolysis for ST elevation myocardial infarction , 2013, Postgraduate Medical Journal.

[17]  K. Sim,et al.  Young coronary artery disease in patients undergoing percutaneous coronary intervention , 2013, Annals of Saudi medicine.

[18]  M. Buchbinder,et al.  A randomized comparison of sirolimus‐eluting versus bare metal stents in the treatment of diabetic patients with native coronary artery lesions: The DECODE study , 2008, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[19]  Karuthan Chinna,et al.  Effect of a reminder system using an automated short message service on medication adherence following acute coronary syndrome , 2015, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

[20]  MTHFR C677T polymorphism, homocysteine and B-vitamins status in a sample of Chinese and Malay subjects in Universiti Putra Malaysia. , 2011, Malaysian journal of nutrition.

[21]  T. Ong,et al.  Subclinical coronary artery disease in Asian rheumatoid arthritis patients who were in remission: a pilot study , 2010, International journal of rheumatic diseases.

[22]  Pulse Wave Velocity as a Marker of Severity of Coronary Artery Disease , 2009, Journal of clinical hypertension.

[23]  J. Deslypere,et al.  Lipids and coronary heart disease in Asia. , 2003, Atherosclerosis.

[24]  M. S. Yousafzai,et al.  The ethnic characteristics and prevalence of diabetes mellitus, hypertension and hyperlipidaemia in patients who underwent coronary artery bypass grafting in Hospital Universiti Kebangsaan Malaysia. , 2002, The Medical journal of Malaysia.

[25]  A. Yeung,et al.  One-year outcomes of percutaneous coronary intervention with the 38-mm Resolute zotarolimus-eluting stent. , 2013, The American journal of cardiology.

[26]  S. Leeder,et al.  Life after myocardial infarction from the perspective of Muslim patients and carers in Malaysia. , 2013, International journal of cardiology.

[27]  M. D. Kamaliah,et al.  Rhabdomyolysis and acute renal failure following a switchover of therapy between two fibric acid derivatives. , 2001, Singapore medical journal.

[28]  R. Conroy,et al.  Inter-Rater and Intra-Rater Reliability of the Bahasa Melayu Version of Rose Angina Questionnaire , 2007, Asia-Pacific journal of public health.

[29]  K. Chew,et al.  A Survey on the Choice of Transportation to come to Emergency Department among Patients with Acute Coronary Syndrome of A Community in Malaysia. , 2015, The Medical journal of Malaysia.

[30]  T. Ong,et al.  Trends of platelet inhibition in different clopidogrel pretreatment patterns in malaysian patients undergoing elective percutaneous coronary intervention. , 2013, The Medical journal of Malaysia.

[31]  H. Matsubara,et al.  Therapeutic angiogenesis for severe ischemic heart diseases by autologous bone marrow cells transplantation , 2004, Molecular and Cellular Biochemistry.

[32]  Ida Zarina Zaini,et al.  Demographic and clinical characteristics of red tag patients and their one-week mortality rate from the emergency department of the Hospital Universiti Sains Malaysia. , 2009, The Southeast Asian journal of tropical medicine and public health.

[33]  S. Voo,et al.  Prevalence of Peripheral Arterial Disease and Abdominal Aortic Aneurysm among Patients with Acute Coronary Syndrome. , 2013, The Medical journal of Malaysia.

[34]  T. Yeow,et al.  Predictors of ischaemic heart disease in a Malaysian population with the metabolic syndrome , 2012, Diabetic medicine : a journal of the British Diabetic Association.

[35]  Yaman Walid Kassab,et al.  Report: trends in adherence to secondary prevention medications in post-acute coronary syndrome patients. , 2015, Pakistan journal of pharmaceutical sciences.

[36]  Purwanto,et al.  Prediction Models for Early Risk Detection of Cardiovascular Event , 2012, Journal of Medical Systems.

[37]  Raja Noor Ainon,et al.  Design of a Fuzzy-based Decision Support System for Coronary Heart Disease Diagnosis , 2012, Journal of Medical Systems.

[38]  S. Azarisman,et al.  Severe left anterior descending artery stenosis with proximal arteriovenous malformation presenting as acute myocardial infarction. , 2009, Singapore medical journal.

[39]  Yaman Walid Kassab,et al.  The impact of pharmacist‐initiated interventions in improving acute coronary syndrome secondary prevention pharmacotherapy prescribing upon discharge , 2013, Journal of clinical pharmacy and therapeutics.

[40]  Z. N. Hanipah,et al.  Previous Radial Artery Harvest for Coronary Artery Bypass Graft Does Not Impede Ipsilateral Proximal Vascular Access Construction , 2015, The journal of vascular access.

[41]  A. Azizi,et al.  Blood pressure variability and arterial elasticity in hyperlipidaemic subjects. , 2008, Singapore medical journal.

[42]  K. Khoo,et al.  Familial hyperlipidaemia in Malaysian children. , 2000, The Medical journal of Malaysia.

[43]  K. Goh,et al.  Ultrasonography-diagnosed non-alcoholic fatty liver disease is not associated with prevalent ischemic heart disease among diabetics in a multiracial Asian hospital clinic population. , 2014, Clinics and research in hepatology and gastroenterology.

[44]  C. Ng,et al.  A primary care experience of open access to exercise stress test. , 2007, The Medical journal of Malaysia.

[45]  O. Maskon,et al.  Left atrial volume index is an independent predictor of major adverse cardiovascular events in acute coronary syndrome. , 2012, The Canadian journal of cardiology.

[46]  Deepak L. Bhatt,et al.  2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2013, Circulation.

[47]  M. A. Tengku,et al.  The association of shift work and hypertension among male factory workers in Kota Bharu, Kelantan, Malaysia. , 2008, The Southeast Asian journal of tropical medicine and public health.

[48]  Aishah Knight,et al.  Association of ABO blood group B with myocardial infarction. , 2009, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[49]  P. Sthaneshwar,et al.  Reference value for cardiac troponin I in a multi‐ethnic group , 2010, Pathology.

[50]  U. Rajendra Acharya,et al.  Automated classification of patients with coronary artery disease using grayscale features from left ventricle echocardiographic images , 2013, Comput. Methods Programs Biomed..

[51]  K. Sim,et al.  Are There Gender Differences in Coronary Artery Disease? The Malaysian National Cardiovascular Disease Database – Percutaneous Coronary Intervention (NCVD-PCI) Registry , 2013, PloS one.

[52]  R. Jamal,et al.  Peripheral blood gene expression profile of atherosclerotic coronary artery disease in patients of different ethnicity in Malaysia. , 2012, Journal of cardiology.

[53]  S. Zainudin,et al.  Utility of Alpha-Blockade in a Hypotensive Pheochromocytoma Patient with Myocardial Infarction , 2014, Medical Principles and Practice.

[54]  W. Ahmad,et al.  The journey of Malaysian NCVD-PCI (National Cardiovascular Disease Database-Percutaneous Coronary Intervention) Registry: a summary of three years report. , 2013, International journal of cardiology.

[55]  Y. Ngeow,et al.  Ethnic distribution of Chlamydophila pneumoniae antibodies in a Malaysian population and possible correlation with coronary heart disease , 2002, European Journal of Epidemiology.

[56]  Akshay S. Desai,et al.  Strategies for multivessel revascularization in patients with diabetes. , 2012, The New England journal of medicine.

[57]  A. Chong,et al.  Heart failure in a multiethnic population in Kuala Lumpur, Malaysia , 2003, European journal of heart failure.

[58]  S. Cheong,et al.  Cryopreserved mesenchymal stromal cell treatment is safe and feasible for severe dilated ischemic cardiomyopathy. , 2010, Cytotherapy.

[59]  A. Sachithanandan,et al.  Coronary artery bypass surgery in a patient with asymptomatic brugada syndrome. , 2013, The Medical journal of Malaysia.

[60]  F. Eberli,et al.  Polymer-free Drug-Coated Coronary Stents. , 2016, The New England journal of medicine.

[61]  M. Z. Dimon,et al.  Renal Outcome Following On- and Off-Pump Coronary Artery Bypass Graft Surgery , 2008, Asian cardiovascular & thoracic annals.

[62]  I. Abidin,et al.  Irreversible delayed complete heart block secondary to jailed first septal perforator following PCI of the left anterior descending coronary artery. , 2012, The Journal of invasive cardiology.

[63]  A. Camm,et al.  Optimising the dichotomy limit for left ventricular ejection fraction in selecting patients for defibrillator therapy after myocardial infarction , 2007, Heart.

[64]  N. Kasim,et al.  Global search for right cell type as a treatment modality for cardiovascular disease , 2014, Expert opinion on biological therapy.

[65]  S. W.,et al.  Evaluation of Aspirin and Clopidogrel resistance in patients with Acute Coronary Syndrome by using Adenosine Diposphate Test and Aspirin Test , 2012, Pakistan journal of medical sciences.

[66]  T. Ong,et al.  CYP2C19 genotypes and their impact on clopidogrel responsiveness in percutaneous coronary intervention , 2013, International Journal of Clinical Pharmacy.

[67]  Mohd Ramzisham Abdul Rahman,et al.  Delayed ascending aortic dissection following off-pump coronary bypass surgery in preexisting stanford B dissection. , 2010, The heart surgery forum.

[68]  N. Kong,et al.  Serum Neutrophil Gelatinase-Associated Lipocalin and Cystatin C are early Biomarkers of Contrast-Induced Nephropathy After Coronary Angiography in Patients With Chronic Kidney Disease , 2014, Angiology.

[69]  Wan Azman Wan Ahmad,et al.  Sex differences in acute coronary syndrome in a multiethnic asian population: results of the malaysian national cardiovascular disease database-acute coronary syndrome (NCVD-ACS) registry. , 2014, Global heart.

[70]  Yaman Walid Kassab,et al.  Use of evidence-based therapy for the secondary prevention of acute coronary syndromes in Malaysian practice. , 2013, Journal of evaluation in clinical practice.

[71]  T. Ong,et al.  Early detection of C-reactive protein and von Willebrand factor levels in Malaysian patients with acute coronary syndrome. , 2013, Journal of cardiovascular disease research.

[72]  Ong Ping Seung,et al.  [Acute myocardial infarction as Eosinophilic granulomatosis with polyangiitis (formerly Churg Strauss syndrome) initial presentation]. , 2014, Revista brasileira de reumatologia.

[73]  O. Maskon,et al.  Aspirin resistance in patients with acute coronary events: risk factors and prevalence as determined by whole blood multiple electrode aggregometry , 2013, Pakistan journal of medical sciences.

[74]  T. Dhanjal,et al.  A COMPARISON OF CARDIOVASCULAR RISK FACTORS AMONG INDO‐ASIAN AND CAUCASIAN PATIENTS ADMITTED WITH ACUTE MYOCARDIAL INFARCTION IN KUALA LUMPUR, MALAYSIA AND BIRMINGHAM, ENGLAND , 2001, International journal of clinical practice.

[75]  I. Abidin Annual Report of the NCVD-PCI Registry year 2007-2009. Jointly published by the National Cardiovascular Disease Database (NCVD) and the Clinical Reasearch Centre (CRC) April 2011 , 2011 .

[76]  K. Sim,et al.  Vessel Density Ratio: A Novel Approach to Identify "Culprit" Coronary Lesion by Spiral Computed Tomography , 2006, Journal of computer assisted tomography.

[77]  C. Teng,et al.  Bibliography of clinical research in malaysia: methods and brief results. , 2014, The Medical journal of Malaysia.

[78]  R. Rajasuriar,et al.  Utilization of Beta blockers post-myocardial infarction. , 2013, The Medical journal of Malaysia.

[79]  K. Sim,et al.  Increased serum levels of interleukin-6 and von Willenbrand Factor in early phase of acute coronary syndrome in a young and multiethnic Malaysian population , 2012, Heart Asia.

[80]  L. H. Yaacob,et al.  Premature Coronary Artery Disease among Angiographically Proven Atherosclerotic Coronary Artery Disease in North East of Peninsular Malaysia , 2013 .

[81]  P. Lee,et al.  The prevalence of cardiovascular risk factors in the young and middle-aged rural population in Sarawak, Malaysia. , 2012, The Malaysian journal of medical sciences : MJMS.

[82]  A. Nordin,et al.  Association of Cholesteryl Ester Transfer Protein and Endothelial Nitric Oxide Synthase Gene Polymorphisms With Coronary Artery Disease in the Multi-Ethnic Malaysian Population , 2016, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

[83]  E. Gupta,et al.  Myocardial infarction false alarm: Initial electrocardiogram and cardiac enzymes , 2014, Asian cardiovascular & thoracic annals.

[84]  M. A. Rosli,et al.  CYP11B2 gene polymorphism among coronary heart disease patients and blood donors in Malaysia. , 2015, The Malaysian journal of pathology.

[85]  K. Yew Overlapping technique for hybrid percutaneous coronary intervention strategy utilising drug eluting stent and ABSORB bioresorbable vascular scaffold. , 2015, International journal of cardiology.

[86]  A. Bulgiba,et al.  Prevalence and predictors of patient adherence to health recommendations after acute coronary syndrome: data for targeted interventions? , 2013, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

[87]  K. Yew Successful treatment of fractional flow reserve wire induced coronary dissection and other coronary de novo lesion with paclitaxel coated balloon only. , 2014, International journal of cardiology.

[88]  T. H. Sasongko,et al.  Analysis of sequence variations in low-density lipoprotein receptor gene among Malaysian patients with familial hypercholesterolemia , 2011, BMC Medical Genetics.

[89]  A. Niedzwiecki,et al.  The effect of multiple micronutrient supplementation on quality of life in patients with symptomatic heart failure secondary to ischemic heart disease: a prospective case series clinical study. , 2015, American journal of cardiovascular disease.

[90]  B. Khoo,et al.  Systemic and coronary levels of CRP, MPO, sCD40L and PlGF in patients with coronary artery disease , 2015, BMC Research Notes.

[91]  M. Sadiq,et al.  Myocardial infarction with normal coronaries: an unexpected finding in a 13-year-old girl with systemic lupus erythematosus , 2013, Lupus.

[92]  B. Zilfalil,et al.  Low-density lipoprotein cholesterol goal attainment among Malaysian dyslipidemic patients. , 2011, The Southeast Asian journal of tropical medicine and public health.

[93]  Raja Noor Ainon,et al.  AMI Screening Using Linguistic Fuzzy Rules , 2012, Journal of Medical Systems.

[94]  B. Khalid,et al.  Use of the denaturing gradient gel electrophoresis (DGGE) method for mutational screening of patients with familial hypercholesterolaemia (FH) and Familial defective apolipoprotein B100 (FDB). , 2006, The Malaysian journal of pathology.

[95]  K. Yusoff Vitamin E in cardiovascular disease: has the die been cast? , 2002, Asia Pacific journal of clinical nutrition.

[96]  U. Kaul,et al.  Evaluation of the XIENCE V everolimus eluting coronary stent system in the Asian population of the SPIRIT V single arm study. 2-year clinical follow-up data. , 2011, Indian heart journal.

[97]  W. Leong,et al.  Coronary artery spasm (CAS) simulating inferior ST elevation myocardial infarction (STEMI). , 2012, The Medical journal of Malaysia.

[98]  Sf Yap,et al.  A RANDOMISED COMPARISON OF SIMVASTATIN VERSUS SIMVASTATIN AND LOW CHOLESTEROL DIET IN THE TREATMENT OF HYPERCHOLESTEROLAEMIA , 2000, International journal of clinical practice.

[99]  S. Ching,et al.  Validation of the pooled cohort risk score in an Asian population – a retrospective cohort study , 2014, BMC Cardiovascular Disorders.

[100]  M Razaz,et al.  How well can signs and symptoms predict AMI in the Malaysian population? , 2005, International journal of cardiology.

[101]  Srijit Das,et al.  Acute myocardial infarction in an adolescent. , 2012, Saudi medical journal.

[102]  K. Sim,et al.  Acute coronary syndrome in women of reproductive age , 2011 .

[103]  K. Yusoff,et al.  Current Status of Coronary Risk Factors Among Rural Malays in Malaysia , 2002, Journal of cardiovascular risk.

[104]  H. Tan Controversy of proton pump inhibitor and clopidogrel interaction: A review , 2010, Journal of digestive diseases.

[105]  I. Aniza,et al.  DEVELOPING THE COST FOR UNCOMPLICATED ACUTE ST ELEVATED MYOCARDIAL INFARCTION (STEMI PRIMARY PERCUTANEOUS CORONARY INTERVENTION) USING STEP DOWN AND ACTIVITY BASED COSTING AT UKMMC. , 2011 .

[106]  S. Shah,et al.  Predictors of mortality in patients with Acute Coronary Syndrome (ACS) undergoing Percutaneous Coronary Intervention (PCI): Insights from National Cardiovascular Disease Database (NCVD), Malaysia. , 2012, The Medical journal of Malaysia.

[107]  Antonio Colombo,et al.  Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial , 2013, The Lancet.

[108]  Zhonghua Sun,et al.  Radiation dose in coronary CT angiography associated with prospective ECG-triggering technique: comparisons with different CT generations. , 2013, Radiation protection dosimetry.

[109]  K. Kamaruddin,et al.  Hand Grip Strength and Myocardial Oxygen Consumption Index among Coronary Artery Bypass Grafting Patients , 2015, Iranian journal of medical sciences.

[110]  Ting Sl,et al.  Asscociation of Risk Factors and Its Bleeding Complication for Tenecteplase Administered in Acute Myocardial Infarction (AMI) , 2013 .

[111]  Mark H. Fisher,et al.  Using neural networks and just nine patient-reportable factors of screen for AMI , 2006, Health Informatics J..

[112]  Srijit Das,et al.  Anxiety and Depression in Patients with Coronary Heart Disease: A Study in a Tertiary Hospital , 2011, Iranian journal of medical sciences.

[113]  J. Deslypere,et al.  Genetic causes of familial hypercholesterolaemia in a Malaysian population. , 2000, The Medical journal of Malaysia.

[114]  R. Nordin,et al.  Ethnic differences in the occurrence of acute coronary syndrome: results of the Malaysian National Cardiovascular Disease (NCVD) Database Registry (March 2006 - February 2010) , 2013, BMC Cardiovascular Disorders.

[115]  Kamarudzaman Md. Isa,et al.  Metabolomics and partial least square discriminant analysis to predict history of myocardial infarction of self-claimed healthy subjects: validity and feasibility for clinical practice , 2015, Journal of Clinical Bioinformatics.

[116]  J. Mohamed,et al.  Anxiety, depression and psychosocial stress in patients with cardiac events. , 2005, The Malaysian journal of medical sciences : MJMS.

[117]  J. Cheah,et al.  Statin alternatives or just placebo: an objective review of omega-3, red yeast rice and garlic in cardiovascular therapeutics. , 2008, Chinese medical journal.

[118]  K. Sim,et al.  Accuracy of 64-row multidetector computed tomography in detecting coronary artery disease in 134 symptomatic patients: influence of calcification. , 2006, American heart journal.

[119]  Khoo Ee Ming,et al.  National Health and Morbidity Survey 2011. , 2012 .

[120]  T. Vos,et al.  Malaysian Burden of Disease and Injury Study , 2005 .

[121]  W. Low,et al.  Factor Structure Of Type D Scale In Malaysian Patients With Coronary Artery Disease , 2014 .

[122]  O. Maskon,et al.  Coronary Artery Bypass Graft in a Young Adult, An Emerging Phenomenon: A Case Report. , 2010 .

[123]  N. M. Shah,et al.  Bleeding Risk Factors with Enoxaparin for Patients with NSTEMI/UA in HUKM , 2008 .