Generation of human monoclonal antibodies by transformation of lymphoblastoid B cells with ras oncogene.

[1]  H. Ikematsu,et al.  Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation. , 1993, Journal of immunology.

[2]  H. Ikematsu,et al.  Somatic Mutations in the VH Genes of High‐Affinity Antibodies to Self and Foreign Antigens Produced by Human CD5+ and CD5− B Lymphocytes a , 1992, Annals of the New York Academy of Sciences.

[3]  H. Ikematsu,et al.  Generation of human monoclonal antibody-producing cell lines by Epstein-Barr virus (EBV)-transformation of B lymphocytes and somatic cell hybridization techniques , 1992 .

[4]  S. Morrison,et al.  In vitro antibodies: strategies for production and application. , 1992, Annual review of immunology.

[5]  César Milstein,et al.  Man-made antibodies , 1991, Nature.

[6]  K. Foon,et al.  Overview of monoclonal antibodies in the diagnosis and therapy of cancer. , 1991, Cancer investigation.

[7]  G. Inghirami,et al.  Negative autoregulation of c‐myc gene expression is inactivated in transformed cells. , 1990, The EMBO journal.

[8]  H. Koprowski,et al.  Influenza virus hemagglutinin-specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[9]  P. Casali,et al.  Frequency of B cells committed to the production of antibodies to insulin in newly diagnosed patients with insulin-dependent diabetes mellitus and generation of high affinity human monoclonal IgG to insulin. , 1990, Journal of immunology.

[10]  N. Harindranath,et al.  Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus , 1990, The Journal of experimental medicine.

[11]  D R Burton,et al.  Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. , 1989, Science.

[12]  Miller Ad,et al.  Improved Retroviral Vectors for Gene Transfer and Expression , 1989 .

[13]  R. Lerner,et al.  Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[14]  J. D. Capra,et al.  Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families. , 1989, Journal of immunology.

[15]  G. Inghirami,et al.  Transformation and plasmacytoid differentiation of EBV-infected human B lymphoblasts by ras oncogenes. , 1989, Science.

[16]  P. Casali,et al.  Probing the human B-cell repertoire with EBV: polyreactive antibodies and CD5+ B lymphocytes. , 1989, Annual review of immunology.

[17]  A. Miller,et al.  Improved retroviral vectors for gene transfer and expression. , 1989, BioTechniques.

[18]  J. Larrick,et al.  Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus. , 1988, Journal of immunology.

[19]  G. Inghirami,et al.  Model for studying virus attachment: identification and quantitation of Epstein-Barr virus-binding cells by using biotinylated virus in flow cytometry , 1988, Journal of virology.

[20]  M. Neuberger,et al.  Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies , 1987, The Journal of experimental medicine.

[21]  K. James,et al.  Human monoclonal antibody production. Current status and future prospects. , 1987, Journal of immunological methods.

[22]  Armentano,et al.  Effect of internal viral sequences on the utility of retroviral vectors , 1987, Journal of virology.

[23]  Larrick Jw,et al.  Prospects for the therapeutic use of human monoclonal antibodies. , 1986 .

[24]  J. Roder,et al.  The EBV-hybridoma technique. , 1986, Methods in enzymology.

[25]  D. Carson,et al.  Human lymphocyte hybridomas and monoclonal antibodies. , 1986, Advances in immunology.

[26]  J. Larrick,et al.  Prospects for the therapeutic use of human monoclonal antibodies. , 1986, Journal of biological response modifiers.

[27]  R. Weinberg,et al.  Specific growth response of ras-transformed embryo fibroblasts to tumour promoters , 1985, Nature.

[28]  E. Gilboa,et al.  Expression of genes introduced into cells by retroviral infection is more efficient than that of genes introduced into cells by DNA transfection , 1984, Journal of virology.

[29]  A. Feinberg,et al.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. , 1983, Analytical biochemistry.

[30]  W. Rutter,et al.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. , 1979, Biochemistry.