Neuroimmunity and the Blood–Brain Barrier: Molecular Regulation of Leukocyte Transmigration and Viral Entry into the Nervous System with a Focus on NeuroAIDS

[1]  J. Berman,et al.  HIV tat and neurotoxicity. , 2006, Microbes and infection.

[2]  J. Berman,et al.  Shedding of PECAM‐1 during HIV infection: a potential role for soluble PECAM‐1 in the pathogenesis of NeuroAIDS , 2006, Journal of leukocyte biology.

[3]  L. Santambrogio,et al.  CD4-Specific Transgenic Expression of Human Cyclin T1 Markedly Increases Human Immunodeficiency Virus Type 1 (HIV-1) Production by CD4+ T Lymphocytes and Myeloid Cells in Mice Transgenic for a Provirus Encoding a Monocyte-Tropic HIV-1 Isolate , 2006, Journal of Virology.

[4]  J. Berman,et al.  CCL2/Monocyte Chemoattractant Protein-1 Mediates Enhanced Transmigration of Human Immunodeficiency Virus (HIV)-Infected Leukocytes across the Blood–Brain Barrier: A Potential Mechanism of HIV–CNS Invasion and NeuroAIDS , 2006, The Journal of Neuroscience.

[5]  J. Ambati,et al.  HIV‐1 Tat and opiate‐induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP‐1 and alternative chemokines , 2006, Glia.

[6]  J. Corbeil,et al.  Methamphetamine stimulates interferon inducible genes in HIV infected brain , 2005, Journal of Neuroimmunology.

[7]  Dominique Schols,et al.  HIV chemokine receptor inhibitors as novel anti-HIV drugs. , 2005, Cytokine & growth factor reviews.

[8]  K. Khalili,et al.  Cross talk between growth factors and viral and cellular factors alters neuronal signaling pathways: Implication for HIV-associated dementia , 2005, Brain Research Reviews.

[9]  A. Ghorpade,et al.  Alcohol‐induced oxidative stress in brain endothelial cells causes blood‐brain barrier dysfunction , 2005, Journal of leukocyte biology.

[10]  A. Lackner,et al.  Simian immunodeficiency virus disrupts extended lengths of the blood–brain barrier , 2005, Journal of medical primatology.

[11]  F. Goebel,et al.  What’s New in HIV/AIDS? Chemokine Receptor Antagonists: A New Era of HIV Therapy? , 2005, Infection.

[12]  H. Xiong,et al.  Neuroprotective Mechanisms of Lithium in Murine Human Immunodeficiency Virus-1 Encephalitis , 2005, The Journal of Neuroscience.

[13]  Dominique Schols,et al.  AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. , 2005, Biochemical pharmacology.

[14]  Wolfgang Löscher,et al.  Drug resistance in brain diseases and the role of drug efflux transporters , 2005, Nature Reviews Neuroscience.

[15]  J. Berman,et al.  NeuroAIDS: Contributions of the human immunodeficiency virus‐1 proteins tat and gp120 as well as CD40 to microglial activation , 2005, Journal of neuroscience research.

[16]  J. Pachter,et al.  CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2. , 2005, Microvascular research.

[17]  Donald W. Miller,et al.  Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise. , 2005, Alcoholism, clinical and experimental research.

[18]  P. Simmonds,et al.  Influence of HAART on HIV-related CNS disease and neuroinflammation. , 2005, Journal of neuropathology and experimental neurology.

[19]  P. Grammas,et al.  HIV-1 gp120 Proteins Alter Tight Junction Protein Expression and Brain Endothelial Cell Permeability: Implications for the Pathogenesis of HIV-Associated Dementia , 2005, Journal of neuropathology and experimental neurology.

[20]  T. Burdo,et al.  Development and characterization of positively selected brain-adapted SIV , 2005, Virology Journal.

[21]  J. Clements,et al.  Neuroprotective and anti-human immunodeficiency virus activity of minocycline. , 2005, JAMA.

[22]  D. Weiner,et al.  Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism , 2005, Cell Death and Differentiation.

[23]  A. Nath,et al.  Synergistic increases in intracellular Ca2+, and the release of MCP‐1, RANTES, and IL‐6 by astrocytes treated with opiates and HIV‐1 Tat , 2005, Glia.

[24]  George M. Shaw,et al.  Simian Immunodeficiency Virus Infection of Chimpanzees , 2005, Journal of Virology.

[25]  C. D. Sharp,et al.  N-methyl-D-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress. , 2005, American journal of physiology. Heart and circulatory physiology.

[26]  A. Brooks,et al.  A mouse model for study of systemic HIV-1 infection, antiviral immune responses, and neuroinvasiveness. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. Berman,et al.  HIV‐1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP‐1)‐dependent mechanism: Possible role in NeuroAIDS , 2005, Glia.

[28]  Raynal C. Squires,et al.  Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice. , 2005, AIDS research and human retroviruses.

[29]  K. Krause,et al.  Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases , 2005, Brain Research Reviews.

[30]  Sieghart Sopper,et al.  HIV-infection of the central nervous system: the tightrope walk of innate immunity. , 2005, Molecular immunology.

[31]  Yong Woo Lee,et al.  Proinflammatory synergism of ethanol and HIV-1 Tat protein in brain tissue , 2005, Experimental Neurology.

[32]  C. Brosnan,et al.  The cytokine IL‐1β transiently enhances P2X7 receptor expression and function in human astrocytes , 2005, Glia.

[33]  K. Marder,et al.  Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia , 2004, Neurology.

[34]  I. Grant,et al.  The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid , 2004, Journal of Neuroimmunology.

[35]  W. Ho,et al.  Substance P and neurokinin-1 receptor modulation of HIV , 2004, Journal of Neuroimmunology.

[36]  H. Fox,et al.  Acute SIV infection of the brain leads to upregulation of IL6 and interferon-regulated genes: expression patterns throughout disease progression and impact on neuroAIDS , 2004, Journal of Neuroimmunology.

[37]  Dominique Schols,et al.  Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist , 2004, Journal of Virology.

[38]  S. Buch,et al.  Investigations on four host response factors whose expression is enhanced in X4 SHIV encephalitis , 2004, Journal of Neuroimmunology.

[39]  J. Clements,et al.  Cerebrospinal fluid markers that predict SIV CNS disease , 2004, Journal of Neuroimmunology.

[40]  N. Volkow,et al.  Decreased brain dopaminergic transporters in HIV-associated dementia patients. , 2004, Brain : a journal of neurology.

[41]  Cynthia Torres,et al.  Modulation by Morphine of Viral Set Point in Rhesus Macaques Infected with Simian Immunodeficiency Virus and Simian-Human Immunodeficiency Virus , 2004, Journal of Virology.

[42]  J. Ghersi-Egea,et al.  Detoxification systems, passive and specific transport for drugs at the blood-CSF barrier in normal and pathological situations. , 2004, Advanced drug delivery reviews.

[43]  S. Fuchs,et al.  Dopaminergic regulation of immune cells via D3 dopamine receptor: a pathway mediated by activated T cells , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[44]  E. Masliah,et al.  Altered P‐Glycoprotein Expression in AIDS Patients with HIV Encephalitis , 2004, Journal of neuropathology and experimental neurology.

[45]  B. Brew,et al.  Independent Evolution of Human Immunodeficiency Virus (HIV) Drug Resistance Mutations in Diverse Areas of the Brain in HIV-Infected Patients, with and without Dementia, on Antiretroviral Treatment , 2004, Journal of Virology.

[46]  M. Mayo,et al.  Association of platelet-derived growth factor-B chain with simian human immunodeficiency virus encephalitis. , 2004, The American journal of pathology.

[47]  H. Xiong,et al.  Memantine Protects Hippocampal Neuronal Function in Murine Human Immunodeficiency Virus Type 1 Encephalitis , 2004, The Journal of Neuroscience.

[48]  Hao-Jie Zhu,et al.  Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism. , 2004, Life sciences.

[49]  J. Esko,et al.  Contribution of Proteoglycans to Human Immunodeficiency Virus Type 1 Brain Invasion , 2004, Journal of Virology.

[50]  A. Ghorpade,et al.  Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: implications for impaired immune function during disease. , 2004, Cellular immunology.

[51]  P. Hordijk,et al.  Signaling in Leukocyte Transendothelial Migration , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[52]  C. Hall,et al.  Highly Active Antiretroviral Therapy Improves Neurocognitive Functioning , 2004, Journal of acquired immune deficiency syndromes.

[53]  T. Terasaki,et al.  A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro , 2004, Journal of neurochemistry.

[54]  P. Riederer,et al.  Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs , 2004, Acta Neuropathologica.

[55]  D. Vestweber,et al.  Junctional adhesion molecules (JAMs): more molecules with dual functions? , 2004, Journal of Cell Science.

[56]  F. Luscinskas,et al.  Regulation of Leukocyte Transmigration: Cell Surface Interactions and Signaling Events 1 , 2004, The Journal of Immunology.

[57]  I. Grant,et al.  Increased human immunodeficiency virus loads in active methamphetamine users are explained by reduced effectiveness of antiretroviral therapy. , 2003, The Journal of infectious diseases.

[58]  C. D. Sharp,et al.  Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor. , 2003, American journal of physiology. Heart and circulatory physiology.

[59]  E. Argyris,et al.  Human Immunodeficiency Virus Type 1 Enters Primary Human Brain Microvascular Endothelial Cells by a Mechanism Involving Cell Surface Proteoglycans Independent of Lipid Rafts , 2003, Journal of Virology.

[60]  Bernhard Hennig,et al.  HIV‐1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells , 2003, Journal of neuroscience research.

[61]  T. Takano,et al.  Signaling at the Gliovascular Interface , 2003, The Journal of Neuroscience.

[62]  N. Berman,et al.  The primary phase of infection by pathogenic simian-human immunodeficiency virus results in disruption of the blood-brain barrier. , 2003, AIDS research and human retroviruses.

[63]  B. Engelhardt Development of the blood-brain barrier , 2003, Cell and Tissue Research.

[64]  J. Berman,et al.  Microglia from mice transgenic for a provirus encoding a monocyte-tropic HIV type 1 isolate produce infectious virus and display in vitro and in vivo upregulation of lipopolysaccharide-induced chemokine gene expression. , 2003, AIDS research and human retroviruses.

[65]  Yong Woo Lee,et al.  HIV-1 tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain , 2003, Molecular and Cellular Neuroscience.

[66]  J. Kornhuber,et al.  Memantine in moderate-to-severe Alzheimer's disease. , 2003, The New England journal of medicine.

[67]  J. Leserman HIV disease progression: depression, stress, and possible mechanisms , 2003, Biological Psychiatry.

[68]  Jane W. Segebrecht,et al.  Microarray analysis of cytokine and chemokine genes in the brains of macaques with SHIV‐encephalitis , 2003, Journal of medical primatology.

[69]  J. Rothstein,et al.  Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120. , 2003, Virology.

[70]  S. Caccia,et al.  Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[71]  W. Muller Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. , 2003, Trends in immunology.

[72]  J. Berman,et al.  MCP‐1 (CCL2) protects human neurons and astrocytes from NMDA or HIV‐tat‐induced apoptosis , 2003, Journal of neurochemistry.

[73]  S. Henriksen,et al.  Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. , 2003, The American journal of pathology.

[74]  T. Rogers,et al.  μ-opioid modulation of HIV-1 coreceptor expressionand HIV-1 replication , 2003 .

[75]  J. Zha,et al.  HIV-1 infection in peripheral blood lymphocytes (PBLs) exposed to alcohol. , 2003, Virology.

[76]  P. Peterson,et al.  Opioid G protein-coupled receptors: signals at the crossroads of inflammation. , 2003, Trends in immunology.

[77]  J. Jäger,et al.  HIV-1 Nef Induces the Release of Inflammatory Factors from Human Monocyte/Macrophages: Involvement of Nef Endocytotic Signals and NF-κB Activation 1 , 2003, The Journal of Immunology.

[78]  J. Berman,et al.  TNF-α Plus IFN-γ Induce Connexin43 Expression and Formation of Gap Junctions Between Human Monocytes/Macrophages That Enhance Physiological Responses 1 , 2003, The Journal of Immunology.

[79]  Yong Woo Lee,et al.  Methamphetamine Potentiates HIV-1 Tat Protein-Mediated Activation of Redox-Sensitive Pathways in Discrete Regions of the Brain , 2003, Experimental Neurology.

[80]  D. Metzger,et al.  Alcohol potentiates HIV-1 infection of human blood mononuclear phagocytes. , 2002, Alcoholism, clinical and experimental research.

[81]  K. Paemeleire The cellular basis of neurovascular metabolic coupling. , 2002, Acta neurologica Belgica.

[82]  J. Clements,et al.  A novel simian immunodeficiency virus model that provides insight into mechanisms of human immunodeficiency virus central nervous system disease. , 2002, Journal of neurovirology.

[83]  R. Kennedy,et al.  HIV‐1 gp120 Proteins and gp160 Peptides Are Toxic to Brain Endothelial Cells and Neurons: Possible Pathway for HIV Entry into the Brain and HIV‐Associated Dementia , 2002, Journal of neuropathology and experimental neurology.

[84]  A. Nath,et al.  Human immunodeficiency virus‐1 Tat protein and methamphetamine interact synergistically to impair striatal dopaminergic function , 2002, Journal of neurochemistry.

[85]  K. Pahan,et al.  Human Immunodeficiency Virus Type 1 (HIV-1) Tat Induces Nitric-oxide Synthase in Human Astroglia* , 2002, The Journal of Biological Chemistry.

[86]  B. Rovin,et al.  HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[87]  A. Nath,et al.  Molecular Basis for Interactions of HIV and Drugs of Abuse , 2002, Journal of acquired immune deficiency syndromes.

[88]  E. Paccagnini,et al.  Substance P antagonist blocks leakage and reduces activation of cytokine-stimulated rat brain endothelium , 2002, Journal of Neuroimmunology.

[89]  S. Mahajan,et al.  Morphine Regulates Gene Expression of α- and β-Chemokines and Their Receptors on Astroglial Cells Via the Opioid μ Receptor1 , 2002, The Journal of Immunology.

[90]  Sunhee C. Lee,et al.  Vpr- and Nef-dependent induction of RANTES/CCL5 in microglial cells. , 2002, Virology.

[91]  D. Kolson,et al.  Chemokine receptors in the brain: their role in HIV infection and pathogenesis. , 2002, AIDS.

[92]  K. Paemeleire Calcium signaling in and between brain astrocytes and endothelial cells. , 2002, Acta neurologica Belgica.

[93]  H. Gendelman,et al.  HIV-1-associated dementia: a basic science and clinical perspective. , 2002, The AIDS reader.

[94]  H. Gu,et al.  Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors , 2002, Psychological Medicine.

[95]  M. Weinand,et al.  Human Immunodeficiency Virus Type 1 Enters Brain Microvascular Endothelia by Macropinocytosis Dependent on Lipid Rafts and the Mitogen-Activated Protein Kinase Signaling Pathway , 2002, Journal of Virology.

[96]  A. Kubar,et al.  Early pericyte response to brain hypoxia in cats: an ultrastructural study. , 2002, Microvascular research.

[97]  Shunji Suzuki,et al.  Morphine promotes simian acquired immunodeficiency syndrome virus replication in monkey peripheral mononuclear cells: induction of CC chemokine receptor 5 expression for virus entry. , 2002, The Journal of infectious diseases.

[98]  V. Sasseville,et al.  Enhanced Expression of Proinflammatory Cytokines in the Central Nervous System Is Associated with Neuroinvasion by Simian Immunodeficiency Virus and the Development of Encephalitis , 2002, Journal of Virology.

[99]  T. Rogers,et al.  Inhibition of morphine-potentiated HIV-1 replication in peripheral blood mononuclear cells with the nuclease-resistant 2-5A agonist analog, 2-5AN6B , 2002 .

[100]  M. Montalto,et al.  Neutrophil-derived Glutamate Regulates Vascular Endothelial Barrier Function* , 2002, The Journal of Biological Chemistry.

[101]  W. Ho,et al.  HIV enhances substance P expression in human immune cells , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[102]  A. Zernecke,et al.  JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes , 2002, Nature Immunology.

[103]  W. Ho,et al.  Substance P enhances HIV-1 replication in latently infected human immune cells , 2001, Journal of Neuroimmunology.

[104]  R. Egleton,et al.  Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier , 2001, Trends in Neurosciences.

[105]  M. Prevost,et al.  Human Immunodeficiency Virus Type 1 Entry into Macrophages Mediated by Macropinocytosis , 2001, Journal of Virology.

[106]  L. Roncali,et al.  Expression of the gap junction protein connexin43 in human telencephalon microvessels. , 2001, Microvascular research.

[107]  J. Clements,et al.  Increased macrophage chemoattractant protein-1 in cerebrospinal fluid precedes and predicts simian immunodeficiency virus encephalitis. , 2001, The Journal of infectious diseases.

[108]  K. Frei,et al.  Molecular and cellular permeability control at the blood–brain barrier , 2001, Brain Research Reviews.

[109]  Jean‐Pierre Martin,et al.  In Vitro Activation of Feline Immunodeficiency Virus in Ramified Microglial Cells from Asymptomatically Infected Cats , 2001, Journal of Virology.

[110]  S. Dewhurst,et al.  Neurotrophins prevent HIV Tat‐induced neuronal apoptosis via a nuclear factor‐κB (NF‐κB)‐dependent mechanism , 2001 .

[111]  S. M. Robinson,et al.  Transport of Human Immunodeficiency Virus Type 1 Pseudoviruses across the Blood-Brain Barrier: Role of Envelope Proteins and Adsorptive Endocytosis , 2001, Journal of Virology.

[112]  R R Rawlings,et al.  Neuroimaging in alcoholism: ethanol and brain damage. , 2001, Alcoholism, clinical and experimental research.

[113]  T. Jernigan,et al.  Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection. , 2001, Brain : a journal of neurology.

[114]  A. Lackner,et al.  Perivascular Macrophages Are the Primary Cell Type Productively Infected by Simian Immunodeficiency Virus in the Brains of Macaques , 2001, The Journal of experimental medicine.

[115]  B. Fiebich,et al.  Minocycline, a Tetracycline Derivative, Is Neuroprotective against Excitotoxicity by Inhibiting Activation and Proliferation of Microglia , 2001, The Journal of Neuroscience.

[116]  D. Vlahov,et al.  Mortality, CD4 cell count decline, and depressive symptoms among HIV-seropositive women: longitudinal analysis from the HIV Epidemiology Research Study. , 2001, JAMA.

[117]  M. Mattson,et al.  Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine , 2001, BMC Neuroscience.

[118]  E. Masliah,et al.  Amelioration of Neurotoxic Effects of HIV Envelope Protein gp120 by Fibroblast Growth Factor: A Strategy for Neuroprotection , 2001, Journal of neuropathology and experimental neurology.

[119]  R. Tanzi,et al.  Uptake of HIV-1 Tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands , 2000, Nature Medicine.

[120]  T. Eisenstein,et al.  μ-Opioid Induction of Monocyte Chemoattractant Protein-1, RANTES, and IFN-γ-Inducible Protein-10 Expression in Human Peripheral Blood Mononuclear Cells1 , 2000, The Journal of Immunology.

[121]  R. Pomerantz,et al.  Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis in Human Neuronal Cells , 2000, Journal of Virology.

[122]  E. Butcher,et al.  The Primate Lentiviral Receptor Bonzo/STRL33 Is Coordinately Regulated with CCR5 and Its Expression Pattern Is Conserved Between Human and Mouse1 , 2000, The Journal of Immunology.

[123]  Yuhui Liu,et al.  Sequential Treatment of SH‐SY5Y Cells with Retinoic Acid and Brain‐Derived Neurotrophic Factor Gives Rise to Fully Differentiated, Neurotrophic Factor‐Dependent, Human Neuron‐Like Cells , 2000, Journal of neurochemistry.

[124]  J. Verhoef,et al.  Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV‐1‐associated dementia , 2000, Neuropathology and applied neurobiology.

[125]  H. Gu,et al.  Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDS. , 2000, The American journal of psychiatry.

[126]  J. Rafols,et al.  Pericyte migration from the vascular wall in response to traumatic brain injury. , 2000, Microvascular research.

[127]  I. Everall,et al.  Recombinant nef HIV-IIIB protein is toxic to human neurons in culture , 2000, Brain Research.

[128]  S. Woodman,et al.  Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation. , 2000, The American journal of pathology.

[129]  C. Raker,et al.  Mice transgenic for monocyte-tropic HIV type 1 produce infectious virus and display plasma viremia: a new in vivo system for studying the postintegration phase of HIV replication. , 2000, AIDS research and human retroviruses.

[130]  S. Gartner HIV Infection and Dementia , 2000, Science.

[131]  E. Eugenin,et al.  Neuropeptide Y induced inhibition of noradrenaline release in rat hypothalamus: role of receptor subtype and nitric oxide , 1999, Brain Research.

[132]  W. Thomas,et al.  Brain macrophages: on the role of pericytes and perivascular cells , 1999, Brain Research Reviews.

[133]  J. Clements,et al.  High Viral Load in the Cerebrospinal Fluid and Brain Correlates with Severity of Simian Immunodeficiency Virus Encephalitis , 1999, Journal of Virology.

[134]  C. Achim,et al.  Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis. , 1999, The American journal of pathology.

[135]  M. Weinand,et al.  Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. , 1999, The American journal of pathology.

[136]  N. Yamamoto,et al.  Induction of blood–brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors , 1999, Neuroscience Research.

[137]  E. Dejana,et al.  Leukocyte Recruitment in the Cerebrospinal Fluid of Mice with Experimental Meningitis Is Inhibited by an Antibody to Junctional Adhesion Molecule (Jam) , 1999, The Journal of experimental medicine.

[138]  M. Pistello,et al.  Tumor necrosis factor-α and virus expression in the central nervous system of cats infected with feline immunodeficiency virus , 1999 .

[139]  V. Sasseville,et al.  HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages , 1999, Nature Medicine.

[140]  J. Weiss,et al.  HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. , 1999, Journal of immunology.

[141]  R. Doms,et al.  Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques. , 1999, Virology.

[142]  W. Tyor,et al.  Do alcohol and cocaine abuse alter the course of HIV‐associated dementia complex? , 1999, Journal of leukocyte biology.

[143]  D. Montefiori,et al.  Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. , 1999, Science.

[144]  Takayuki Itoh,et al.  Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates , 1999, Journal of Virology.

[145]  E. Paccagnini,et al.  HIV‐1 gp120 increases the permeability of rat brain endothelium cultures by a mechanism involving substance P , 1998, AIDS.

[146]  F. Joó,et al.  Expression of glutamate receptors on cultured cerebral endothelial cells , 1998, Journal of neuroscience research.

[147]  W. Kelder,et al.  β‐Chemokines MCP‐1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus–associated dementia , 1998 .

[148]  J. Lai,et al.  Functional studies in cultured astrocytes. , 1998, Methods.

[149]  T. Owens,et al.  Immune cell entry to the CNS--a focus for immunoregulation of EAE. , 1998, Research in immunology.

[150]  R. Doms,et al.  An Orphan Seven-Transmembrane Domain Receptor Expressed Widely in the Brain Functions as a Coreceptor for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus , 1998, Journal of Virology.

[151]  C. Achim,et al.  Chemokines and receptors in HIV encephalitis , 1998, AIDS.

[152]  H. Kleinman,et al.  Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. , 1998, Circulation research.

[153]  E. Dejana,et al.  Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration , 1998, The Journal of cell biology.

[154]  J. Catalan,et al.  Risk of HIV dementia and opportunistic brain disease in AIDS and zidovudine therapy , 1998, Journal of neurology, neurosurgery, and psychiatry.

[155]  C. Achim,et al.  Haptoglobin polymorphism, iron metabolism and mortality in HIV infection , 1998 .

[156]  D. Gabuzda,et al.  Chemokine receptors in HIV-1 infection of the central nervous system. , 1998, Seminars in immunology.

[157]  P. Marx,et al.  The function of simian chemokine receptors in the replication of SIV. , 1998, Seminars in immunology.

[158]  H. Gendelman,et al.  SCID mice with HIV encephalitis develop behavioral abnormalities. , 1998, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

[159]  E. Major,et al.  Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[160]  K. Crandall,et al.  Cocaine abuse and HIV-1 infection: Epidemiology and neuropathogenesis , 1998, Journal of Neuroimmunology.

[161]  A. Kastin,et al.  Adsorptive endocytosis mediates the passage of HIV-1 across the blood-brain barrier: evidence for a post-internalization coreceptor. , 1998, Journal of cell science.

[162]  F. Bloom,et al.  Simian Immunodeficiency Virus: A Model for NeuroAIDS , 1997, Neurobiology of Disease.

[163]  M. Clerici,et al.  Apoptotic cell death and cytokine dysregulation in human immunodeficiency virus infection: pivotal factors in disease progression , 1997, Cell Death and Differentiation.

[164]  M. Weinand,et al.  TNF-α Opens a Paracellular Route for HIV-1 Invasion across the Blood-Brain Barrier , 1997 .

[165]  B R Johansson,et al.  Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. , 1997, Science.

[166]  L. Foresman,et al.  Neuropathogenesis of Chimeric Simian/Human Immunodeficiency Virus infection In Pig‐tailed and Rhesus Macaques , 1997, Brain pathology.

[167]  S. Crowe,et al.  Effects of HIV-1 on the surface expression of LFA-1 on cultured monocytes. , 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

[168]  C. Broder,et al.  Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[169]  C. Duyckaerts,et al.  Astrocytic adhesion molecules are increased in HIV‐1‐associated cognitive/motor complex , 1997, Neuropathology and applied neurobiology.

[170]  M. Weinand,et al.  A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis. , 1997, Journal of immunology.

[171]  M. Dehouck,et al.  Endothelin-1 as a Mediator of Endothelial Cell–Pericyte Interactions in Bovine Brain Capillaries , 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[172]  D. Perkins,et al.  Severe stress, depressive symptoms, and changes in lymphocyte subsets in human immunodeficiency virus-infected men. A 2-year follow-up study. , 1997, Archives of general psychiatry.

[173]  M. Verbeek,et al.  Rapid Degeneration of Cultured Human Brain Pericytes by Amyloid β Protein , 1997 .

[174]  V G Sasseville,et al.  Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis. , 1996, The American journal of pathology.

[175]  Brigitte L. Kieffer,et al.  Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene , 1996, Nature.

[176]  T. Clark,et al.  Investigation of the Uncatalyzed Hydration of CO2 and First Approximations to the Active Site of Carbonic Anhydrase - A Combined Ab initio and DFT Study - , 1996 .

[177]  M. Tashiro,et al.  Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cells , 1996, FEBS letters.

[178]  H. Gendelman,et al.  Human immunodeficiency virus encephalitis in SCID mice. , 1996, The American journal of pathology.

[179]  G. Nuovo,et al.  AIDS Dementia Is Associated with Massive, Activated HIV-1 Infection and Concomitant Expression of Several Cytokines , 1996, Molecular medicine.

[180]  U. Hengge,et al.  Increased neuropeptide Y-like immunoreactivity in cerebrospinal fluid and plasma of human immunodeficiency virus-infected patients: relationship to HIV encephalopathy , 1996, Journal of the Neurological Sciences.

[181]  T. Kern,et al.  Capillary lesions develop in retina rather than cerebral cortex in diabetes and experimental galactosemia. , 1996, Archives of ophthalmology.

[182]  H. Gendelman,et al.  Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. , 1996, Journal of immunology.

[183]  D. Rusyniak,et al.  HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures , 1995, Brain Research.

[184]  R. Bravo,et al.  Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. , 1995, Journal of immunology.

[185]  S. Arya,et al.  Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8+ T Cells , 1995, Science.

[186]  M. Fallon,et al.  Ca2+ waves are organized among hepatocytes in the intact organ. , 1995, American Journal of Physiology.

[187]  J. Clements,et al.  Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro , 1994, Journal of virology.

[188]  A. Lackner,et al.  Early events in tissues during infection with pathogenic (SIVmac239) and nonpathogenic (SIVmac1A11) molecular clones of simian immunodeficiency virus. , 1994, The American journal of pathology.

[189]  H. Morgenstern,et al.  Depressive symptoms as predictors of medical outcomes in HIV infection. Multicenter AIDS Cohort Study. , 1993, JAMA.

[190]  M. Chesney,et al.  Depressive symptoms and CD4 lymphocyte decline among HIV-infected men. , 1993, JAMA.

[191]  H. Morgenstern,et al.  Depressive Symptoms as Predictors of Medical Outcomes in HIV Infection , 1993 .

[192]  F E Bloom,et al.  Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[193]  H. Gendelman,et al.  A model of human immunodeficiency virus encephalitis in scid mice. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[194]  M. Hirsch,et al.  Zidovudine treatment of the AIDS dementia complex: Results of a placebo‐controlled trial , 1993, Annals of neurology.

[195]  D. Healy,et al.  Localization of immunoreactive glutamyl aminopeptidase in rat brain. II. Distribution and correlation with angiotensin II , 1993, Brain Research.

[196]  C. Brosnan,et al.  Chronic inflammatory effects of interleukin-1 on the blood-retina barrier , 1992, Journal of Neuroimmunology.

[197]  C. Weisse,et al.  Depression and immunocompetence: a review of the literature. , 1992, Psychological bulletin.

[198]  E. Murray,et al.  Cognitive and motor impairments associated with SIV infection in rhesus monkeys. , 1992, Science.

[199]  A. Adachi,et al.  SIV/HIV recombinants and their use in studying biological properties. , 1992, AIDS research and human retroviruses.

[200]  W. Risau,et al.  Induction of Blood‐Brain Barrier Endothelial Cell Differentiation a , 1991, Annals of the New York Academy of Sciences.

[201]  A. Ishimoto,et al.  Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells , 1991, Journal of virology.

[202]  R. Weiss,et al.  Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus , 1991, Virology.

[203]  W. Pardridge,et al.  Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. , 1990, The Journal of pharmacology and experimental therapeutics.

[204]  R. Desrosiers,et al.  HIV-related lentiviruses of nonhuman primates. , 1989, AIDS research and human retroviruses.

[205]  A. Dalgleish,et al.  Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells , 1989, Nature.

[206]  R. Ravid,et al.  Immunocytochemically stained vasopressin binding sites on blood vessels in the rat brain , 1988, Brain Research.

[207]  W. Pardridge,et al.  Neutral amino acid transport at the human blood-brain barrier. , 1986, Federation proceedings.

[208]  A. Lajtha THE DEVELOPMENT OF THE BLOOD‐BRAIN BARRIER * , 1957 .

[209]  M. Weed,et al.  Neuropsychopathology in the SIV/macaque model of AIDS. , 2005, Frontiers in bioscience : a journal and virtual library.

[210]  Manish Kumar,et al.  Nef: "necessary and enforcing factor" in HIV infection. , 2005, Current HIV research.

[211]  R. Fariello,et al.  Nigral degeneration in acquired immune deficiency syndrome (AIDS) , 2004, Acta Neuropathologica.

[212]  D. Robertson,et al.  The history of SIVS and AIDS: epidemiology, phylogeny and biology of isolates from naturally SIV infected non-human primates (NHP) in Africa. , 2004, Frontiers in bioscience : a journal and virtual library.

[213]  T. Rogers,et al.  Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication. , 2003, Virology.

[214]  J. Jäger,et al.  HIV-1 Nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of Nef endocytotic signals and NF-kappa B activation. , 2003, Journal of immunology.

[215]  J. Berman,et al.  TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses. , 2003, Journal of immunology.

[216]  T. Rogers,et al.  Inhibition of morphine-potentiated HIV-1 replication in peripheral blood mononuclear cells with the nuclease-resistant 2-5A agonist analog, 2-5A(N6B). , 2002, Journal of acquired immune deficiency syndromes.

[217]  W. Muller,et al.  CD99 plays a major role in the migration of monocytes through endothelial junctions , 2002, Nature Immunology.

[218]  S. Mahajan,et al.  Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu receptor. , 2002, Journal of immunology.

[219]  D. Janigro,et al.  The blood-brain barrier and AIDS. , 2001, Advances in virus research.

[220]  Dieter J. Meyerhoff,et al.  Effects of Alcohol and HIV Infection on the Central Nervous System , 2001, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

[221]  J. Lawrenson,et al.  Contractile proteins in pericytes at the blood-brain and blood-retinal barriers , 2001, Journal of neurocytology.

[222]  S. Dewhurst,et al.  Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. , 2001, Journal of neurochemistry.

[223]  M. Sanderson,et al.  Astrocyte-endothelial cell calcium signals conveyed by two signalling pathways. , 2001, The European journal of neuroscience.

[224]  T. Eisenstein,et al.  Mu-opioid induction of monocyte chemoattractant protein-1, RANTES, and IFN-gamma-inducible protein-10 expression in human peripheral blood mononuclear cells. , 2000, Journal of immunology.

[225]  Jianbin Wang,et al.  Chemokine receptors and virus entry in the central nervous system. , 1999, Journal of neurovirology.

[226]  L. Rubin,et al.  The cell biology of the blood-brain barrier. , 1999, Annual review of neuroscience.

[227]  D. Perkins,et al.  Progression to AIDS: the effects of stress, depressive symptoms, and social support. , 1999, Psychosomatic medicine.

[228]  E. Benveniste,et al.  Human immunodeficiency virus type 1 TAT protein induces adhesion molecule expression in astrocytes. , 1999, Journal of neurovirology.

[229]  M. Pistello,et al.  Tumor necrosis factor-alpha and virus expression in the central nervous system of cats infected with feline immunodeficiency virus. , 1999, Journal of neurovirology.

[230]  S. Lipton Neuronal injury associated with HIV-1: approaches to treatment. , 1998, Annual review of pharmacology and toxicology.

[231]  D. Taub,et al.  Cocaine opens the blood-brain barrier to HIV-1 invasion. , 1998, Journal of neurovirology.

[232]  J. Clements,et al.  SIV infection of macaques--modeling the progression to AIDS dementia. , 1998, Journal of neurovirology.

[233]  S. D. House,et al.  Cocaine enhances monocyte migration across the blood-brain barrier. Cocaine's connection to AIDS dementia and vasculitis? , 1998, Advances in experimental medicine and biology.

[234]  D. Kolson,et al.  Chemokine receptors in the human brain and their relationship to HIV infection. , 1998, Journal of neurovirology.

[235]  M. Weinand,et al.  TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier. , 1997, Molecular medicine.

[236]  M. Verbeek,et al.  Rapid degeneration of cultured human brain pericytes by amyloid beta protein. , 1997, Journal of neurochemistry.

[237]  M. Buchmeier,et al.  Expression of Inflammatory Cytokines and Inducible Nitric Oxide Synthase in Brains of SIV-Infected Rhesus Monkeys: Applications to HIV-Induced Central Nervous System Disease , 1996, Molecular medicine.

[238]  M. Weinand,et al.  Divergent effects of cocaine on cytokine production by lymphocytes and monocyte/macrophages: HIV-1 enhancement by cocaine within the blood-brain barrier. , 1996, Advances in experimental medicine and biology.

[239]  B. Brando,et al.  Flow cytometry cross-match. , 1996, European journal of histochemistry : EJH.

[240]  M. Weinand,et al.  Divergent Effects of Cocaine on Cytokine Production by Lymphocytes and Monocyte/Macroophages , 1996 .

[241]  A. Herz [Neurobiological principles of drug dependence. Exemplified by opioids and psychostimulants]. , 1995, Der Nervenarzt.

[242]  S. Arya,et al.  Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. , 1995, Science.

[243]  S. Lipton HIV-related neuronal injury. Potential therapeutic intervention with calcium channel antagonists and NMDA antagonists. , 1994, Molecular neurobiology.

[244]  J. Clements,et al.  The SIV model of AIDS encephalopathy. Role of neurotropic viruses in diseases. , 1994, Research publications - Association for Research in Nervous and Mental Disease.

[245]  J. Berman,et al.  The role of the blood-brain barrier in HIV infection of the central nervous system. , 1994, Advances in neuroimmunology.

[246]  R. Dantzer,et al.  Stress and immunity: an integrated view of relationships between the brain and the immune system. , 1989, Life sciences.

[247]  C. Pedersen,et al.  Immune correlates of stress and depression. , 1989, Psychopharmacology bulletin.

[248]  C. Sladek,et al.  Adrenergic receptors on cerebral microvessels: pericyte contribution. , 1989, The American journal of physiology.

[249]  J. Conomy,et al.  The neurology of AIDS. , 1989, Singapore medical journal.