Gold nanoshells for imaging and photothermal ablation of cancer

Abstract: Gold nanoshells consist of a thin, gold shell over a non-conductive core material, such as silica or gold-sulfide. Designed to scatter and absorb light within the near-infrared (NIR) water window, these particles can be employed for both optical imaging and photothermal ablation of cancer. This chapter provides a brief overview of nanotechnology’s role in cancer medicine followed by an in-depth discussion of gold nanoshells, their optical properties and use thus far as a cancer diagnostic and therapeutic tool in vitro and in vivo.

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