Per1/Per2 double knockout transcriptome analysis reveals circadian regulation of hepatic lipid metabolism

[1]  Chao-ke Tang,et al.  Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis. , 2021, Progress in lipid research.

[2]  Hualin Wang,et al.  DHA substitution overcomes high-fat diet-induced disturbance in the circadian rhythm of lipid metabolism. , 2020, Food & function.

[3]  Jie Luo,et al.  Mechanisms and regulation of cholesterol homeostasis , 2019, Nature Reviews Molecular Cell Biology.

[4]  Mengcheng Ruan,et al.  ω-3 PUFAs Alleviate High-fat Diet Induced Circadian Intestinal Microbes Dysbiosis. , 2019, Molecular nutrition & food research.

[5]  Liping Wei,et al.  Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1 , 2019, Molecules.

[6]  Guoxun Chen,et al.  Fish oil alleviates circadian bile composition dysregulation in male mice with NAFLD. , 2019, The Journal of nutritional biochemistry.

[7]  G. Hostetter,et al.  Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer. , 2019, Personalized medicine.

[8]  J. Brüning,et al.  Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma , 2018, Molecular metabolism.

[9]  W. Syn,et al.  Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease , 2018, Digestive Diseases and Sciences.

[10]  Derek J Van Booven,et al.  Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver , 2018, Scientific Reports.

[11]  L. Vissers,et al.  Squalene Synthase Deficiency: Clinical, Biochemical, and Molecular Characterization of a Defect in Cholesterol Biosynthesis. , 2018, American journal of human genetics.

[12]  Xifeng Zhang,et al.  Fish Oil Ameliorates High-Fat Diet Induced Male Mouse Reproductive Dysfunction via Modifying the Rhythmic Expression of Testosterone Synthesis Related Genes , 2018, International journal of molecular sciences.

[13]  D. Hwang,et al.  RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network , 2017, Nature Communications.

[14]  S. Vasudevan,et al.  The genetics of circadian rhythms, sleep and health , 2017, Human molecular genetics.

[15]  Achim Kramer,et al.  Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator , 2016, PLoS Comput. Biol..

[16]  S. Panda,et al.  Circadian physiology of metabolism , 2016, Science.

[17]  C. Bradfield,et al.  Global and hepatocyte-specific ablation of Bmal1 induces hyperlipidaemia and enhances atherosclerosis , 2016, Nature Communications.

[18]  H. Sone,et al.  Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice , 2016, PloS one.

[19]  J. Gooley Circadian regulation of lipid metabolism , 2016, Proceedings of the Nutrition Society.

[20]  Jiali Liu,et al.  Free fatty acids, not triglycerides, are associated with non-alcoholic liver injury progression in high fat diet induced obese rats , 2016, Lipids in Health and Disease.

[21]  D. Erion,et al.  Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice. , 2016, Endocrinology.

[22]  Lei He,et al.  Fish oil alleviated high-fat diet–induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study , 2016, Lipids in Health and Disease.

[23]  Jiandie D. Lin,et al.  The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis* , 2015, The Journal of Biological Chemistry.

[24]  K. Gamble,et al.  The Molecular Circadian Clock and Alcohol-Induced Liver Injury , 2015, Biomolecules.

[25]  C. Cannon,et al.  PCSK9 (Proprotein convertase subtilisin/kexin type 9) inhibitors: past, present, and the future. , 2015, European heart journal.

[26]  D. Moore,et al.  Circadian Dysfunction Induces Leptin Resistance in Mice. , 2015, Cell metabolism.

[27]  J. Rahnenführer,et al.  Loss of circadian clock gene expression is associated with tumor progression in breast cancer , 2014, Cell cycle.

[28]  D. Belsham,et al.  Differential effects of omega-3 fatty acid docosahexaenoic acid and palmitate on the circadian transcriptional profile of clock genes in immortalized hypothalamic neurons. , 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

[29]  L. Fu,et al.  Circadian gene variants in cancer , 2014, Annals of medicine.

[30]  Soon B. Hwang,et al.  Farnesyl‐diphosphate farnesyltransferase 1 regulates hepatitis C virus propagation , 2014, FEBS letters.

[31]  A. Ferramosca,et al.  Modulation of hepatic steatosis by dietary fatty acids. , 2014, World journal of gastroenterology.

[32]  Xianlin Han,et al.  Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. , 2014, Cell metabolism.

[33]  Ping Yang,et al.  Deletion of circadian gene Per1 alleviates acute ethanol-induced hepatotoxicity in mice. , 2013, Toxicology.

[34]  J. Chiang Bile acid metabolism and signaling. , 2013, Comprehensive Physiology.

[35]  G. Eichele,et al.  Circadian Clock Genes Per1 and Per2 Regulate the Response of Metabolism-Associated Transcripts to Sleep Disruption , 2012, PloS one.

[36]  J. Takahashi,et al.  Central and peripheral circadian clocks in mammals. , 2012, Annual review of neuroscience.

[37]  Eric F. Johnson,et al.  5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-Stimulated Hepatic Expression of Cyp4a10, Cyp4a14, Cyp4a31, and Other Peroxisome Proliferator-Activated Receptor α-Responsive Mouse Genes Is AICAR 5′-Monophosphate-Dependent and AMP-Activated Protein Kinase-Independent , 2011, Journal of Pharmacology and Experimental Therapeutics.

[38]  K. Yamamoto,et al.  Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate* , 2011, The Journal of Biological Chemistry.

[39]  C. Ker,et al.  Leptin in hepatocellular carcinoma. , 2010, World journal of gastroenterology.

[40]  P. Sassone-Corsi,et al.  PER2 controls lipid metabolism by direct regulation of PPARγ. , 2010, Cell metabolism.

[41]  C. Klaassen,et al.  Circadian Expression Profiles of Drug-Processing Genes and Transcription Factors in Mouse Liver , 2009, Drug Metabolism and Disposition.

[42]  Kathryn Moynihan Ramsey,et al.  High-fat diet disrupts behavioral and molecular circadian rhythms in mice. , 2007, Cell metabolism.

[43]  F. Claessens,et al.  Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation* , 2007, Journal of Biological Chemistry.

[44]  Cheng Chi Lee Tumor Suppression by the Mammalian Period Genes , 2006, Cancer Causes & Control.

[45]  S. Shimba,et al.  Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[46]  Fred W. Turek,et al.  Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice , 2005, Science.

[47]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[48]  Gregor Eichele,et al.  Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock , 2001, Cell.

[49]  S. Shibata,et al.  Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet. , 2008, American journal of physiology. Endocrinology and metabolism.