Experimental effects of Saccharomyces boulardii on diarrheal pathogens.

Saccharomyces boulardii is a selected strain of yeast that may have applications in the prevention and treatment of intestinal infections. The animal models and in vitro studies developed to elucidate the mechanisms of this protection are reviewed and discussed.

[1]  P. Marteau,et al.  Protection from gastrointestinal diseases with the use of probiotics. , 2001, The American journal of clinical nutrition.

[2]  S. Dahan,et al.  Saccharomyces boulardii Preserves the Barrier Function and Modulates the Signal Transduction Pathway Induced in Enteropathogenic Escherichia coli-Infected T84 Cells , 2000, Infection and Immunity.

[3]  P. Rampal,et al.  Saccharomyces boulardii inhibits secretagogue-mediated adenosine 3',5'-cyclic monophosphate induction in intestinal cells. , 1994, Gastroenterology.

[4]  L. Mcfarland,et al.  Biotherapeutic agents in the treatment of infectious diarrhea. , 2001, Gastroenterology clinics of North America.

[5]  E. Bambirra,et al.  Protective effect of Saccharomyces boulardii against the cholera toxin in rats. , 1995, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[6]  Larry K. Pickering,et al.  Infections of the Gastrointestinal Tract , 1980, Current Topics in Infectious Disease.

[7]  B. Finlay,et al.  Listeria monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-Activated Protein Kinase Pathway , 1998, Infection and Immunity.

[8]  G. Corthier,et al.  Prevention of Clostridium difficile induced mortality in gnotobiotic mice by Saccharomyces boulardii. , 1986, Canadian journal of microbiology.

[9]  P. Rampal,et al.  [Response to cholera toxin of 2 epithelial intestinal cell lines. Effect of Saccharomyces boulardii]. , 1989, Gastroenterologie clinique et biologique.

[10]  R. Fuller,et al.  Probiotics in human medicine. , 1991, Gut.

[11]  G. Cardinali,et al.  Electrophoretic karyotypes of authentic strains of the sensu stricto group of the genus Saccharomyces. , 1994, International journal of systematic bacteriology.

[12]  G. Corthier,et al.  Prevention of Clostridium difficile-induced experimental pseudomembranous colitis by Saccharomyces boulardii: a scanning electron microscopic and microbiological study. , 1990, Journal of general microbiology.

[13]  C. Pothoulakis,et al.  Saccharomyces boulardii Stimulates Intestinal Immunoglobulin A Immune Response to Clostridium difficileToxin A in Mice , 2001, Infection and Immunity.

[14]  N. Vidon,et al.  [Influence of Saccharomyces boulardii on jejunal secretion in rats induced by cholera toxin]. , 1986, Gastroenterologie clinique et biologique.

[15]  J. Thomas LaMont,et al.  Saccharomyces boulardii Protease Inhibits the Effects of Clostridium difficile Toxins A and B in Human Colonic Mucosa , 1999, Infection and Immunity.

[16]  C. Surawicz,et al.  A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease. , 1994, JAMA.

[17]  C. Pothoulakis,et al.  Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. , 1993, Gastroenterology.

[18]  E. Bambirra,et al.  Effect of Saccharomyces boulardii against experimental oral infection with Salmonella typhimurium and Shigella flexneri in conventional and gnotobiotic mice. , 1996, The Journal of applied bacteriology.

[19]  C. Surawicz,et al.  The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii. , 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[20]  P. Rampal,et al.  [Response of the IRD intestinal epithelial cell line to Clostridium difficile toxins A and B in rats. Effect of Saccharomyces boulardii]. , 1991, Gastroenterologie clinique et biologique.

[21]  A. Querol,et al.  Fungemia with Saccharomyces cerevisiae in Two Newborns, Only One of Whom Had Been Treated with Ultra-Levura , 2000, European Journal of Clinical Microbiology and Infectious Diseases.

[22]  Luciano G. Fietto,et al.  Intracellular Signal Triggered by Cholera Toxin inSaccharomyces boulardii and Saccharomyces cerevisiae , 1998, Applied and Environmental Microbiology.

[23]  H. Bléhaut,et al.  Disposition kinetics of Saccharomyces boulardii in man and rat. , 1989, Biopharmaceutics & drug disposition.

[24]  P. Rampal,et al.  Effect of Saccharomyces boulardii on cAMP- and Ca2+-dependent Cl- Secretion in T84 Cells , 1999, Digestive Diseases and Sciences.

[25]  B. Dujon,et al.  Microsatellite Typing as a New Tool for Identification of Saccharomyces cerevisiae Strains , 2001, Journal of Clinical Microbiology.

[26]  J. Jacquemin,et al.  Possible Role of Catheters in Saccharomyces boulardii Fungemia , 2000, European Journal of Clinical Microbiology and Infectious Diseases.

[27]  G. Dougan,et al.  Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements , 1998, Molecular microbiology.

[28]  C. Surawicz,et al.  Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. , 1996, JAMA.

[29]  G. Elmer,et al.  Prevention of clindamycin-induced mortality in hamsters by Saccharomyces boulardii , 1984, Antimicrobial Agents and Chemotherapy.

[30]  C. Pothoulakis,et al.  Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum , 1996, Infection and immunity.

[31]  Y. Vandenplas,et al.  Micro‐organisms administered in the benefit of the host: myths and facts , 2000, European journal of gastroenterology & hepatology.

[32]  G. Corthier,et al.  Modulation of Clostridium difficile induced mortality as a function of the dose and the viability of the Saccharomyces boulardii used as a preventative agent in gnotobiotic mice. , 1991, Canadian journal of microbiology.

[33]  M. Craynest,et al.  Response of Human and Rat Small Intestinal Mucosa to Oral Administration of Saccharomyces boulardii , 1986, Pediatric Research.