Essential Role for TrkB Receptors in Hippocampus-Mediated Learning

[1]  L. Zhang,et al.  Impairments in High-Frequency Transmission, Synaptic Vesicle Docking, and Synaptic Protein Distribution in the Hippocampus of BDNF Knockout Mice , 1999, The Journal of Neuroscience.

[2]  H. Eichenbaum,et al.  The Hippocampus, Memory, and Place Cells Is It Spatial Memory or a Memory Space? , 1999, Neuron.

[3]  E. Huang,et al.  Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC. , 1999, Development.

[4]  P. Wahle,et al.  Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures , 1999, The European journal of neuroscience.

[5]  J. Lisman.  Relating Hippocampal Circuitry to Function Recall of Memory Sequences by Reciprocal Dentate–CA3 Interactions , 1999, Neuron.

[6]  E. Casanova,et al.  Inducible site-specific recombination in the brain. , 1999, Journal of molecular biology.

[7]  L C Katz,et al.  Neurotrophins and synaptic plasticity. , 1999, Annual review of neuroscience.

[8]  H. Lester,et al.  Enhancement of Neurotransmitter Release Induced by Brain-Derived Neurotrophic Factor in Cultured Hippocampal Neurons , 1998, The Journal of Neuroscience.

[9]  R. Morris,et al.  Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein , 1998, Nature.

[10]  M. Ammassari-Teule,et al.  What do comparative studies of inbred mice add to current investigations on the neural basis of spatial behaviors? , 1998, Experimental Brain Research.

[11]  M. Barbacid,et al.  TrkB and TrkC Signaling Are Required for Maturation and Synaptogenesis of Hippocampal Connections , 1998, The Journal of Neuroscience.

[12]  J. Roder,et al.  Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP , 1998, Behavioural Brain Research.

[13]  R. Mair,et al.  Lesions of the frontal cortex, hippocampus, and intralaminar thalamic nuclei have distinct effects on remembering in rats. , 1998, Behavioral neuroscience.

[14]  C. Stucky,et al.  Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses , 1998, Neuron.

[15]  K. Wada,et al.  Association of the Src Family Tyrosine Kinase Fyn with TrkB , 1998, Journal of neurochemistry.

[16]  M. Segal,et al.  Hippocampal Synaptic Plasticity in Mice Overexpressing an Embryonic Subunit of the NMDA Receptor , 1998, The Journal of Neuroscience.

[17]  David P Wolfer,et al.  Genetically modified mice and cognition , 1998, Current Opinion in Neurobiology.

[18]  C. Shatz,et al.  Competition in retinogeniculate patterning driven by spontaneous activity. , 1998, Science.

[19]  G. Higgins,et al.  Characterization of perforant path lesions in rodent models of memory and attention , 1998, The European journal of neuroscience.

[20]  M. Packard,et al.  Amygdala Modulation of Multiple Memory Systems: Hippocampus and Caudate-Putamen , 1998, Neurobiology of Learning and Memory.

[21]  E. Kandel,et al.  Cognitive Neuroscience and the Study of Memory , 1998, Neuron.

[22]  H. Thoenen,et al.  Reduced Size of Retinal Ganglion Cell Axons and Hypomyelination in Mice Lacking Brain-Derived Neurotrophic Factor , 1997, Molecular and Cellular Neuroscience.

[23]  S. Linnarsson,et al.  Learning Deficit in BDNF Mutant Mice , 1997, The European journal of neuroscience.

[24]  Steven Finkbeiner,et al.  CREB: A Major Mediator of Neuronal Neurotrophin Responses , 1997, Neuron.

[25]  Anirvan Ghosh,et al.  Neurotrophins: New roles for a seasoned cast , 1997, Current Biology.

[26]  H. R. Griffith,et al.  The Flexible Use of Multiple Cue Relationships in Spatial Navigation: A Comparison of Water Maze Performance Following Hippocampal, Medial Septal, Prefrontal Cortex, or Posterior Parietal Cortex Lesions , 1997, Neurobiology of Learning and Memory.

[27]  M. Ammassari-Teule,et al.  The dorsal hippocampus is selectively involved in the processing of spatial information even in mice with a genetic hippocampal dysfunction , 1997, Psychobiology.

[28]  J R Sanes,et al.  Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates. , 1997, Science.

[29]  M. Barbacid,et al.  TrkB Signaling Is Required for Postnatal Survival of CNS Neurons and Protects Hippocampal and Motor Neurons from Axotomy-Induced Cell Death , 1997, The Journal of Neuroscience.

[30]  I. Fariñas,et al.  The role of neurotrophic factors in regulating the development of inner ear innervation , 1997, Trends in Neurosciences.

[31]  A. Berns,et al.  Cre-mediated somatic site-specific recombination in mice. , 1997, Nucleic acids research.

[32]  D. Kaplan,et al.  Signal transduction by the neutrophin receptors , 1997 .

[33]  J. D. Brabander,et al.  Response learning of rats in a Morris water maze: Involvement of the medial prefrontal cortex , 1997, Behavioural Brain Research.

[34]  F. Holsboer,et al.  Intact spatial learning and memory in transgenic mice with reduced BDNF , 1997, Neuroreport.

[35]  R. Paylor,et al.  Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. , 1997, Behavioral neuroscience.

[36]  A. Davies,et al.  Neurotrophins: The yin and yang of nerve growth factor , 1997, Current Biology.

[37]  Xian-Min Yu,et al.  NMDA Channel Regulation by Channel-Associated Protein Tyrosine Kinase Src , 1997, Science.

[38]  C Chen,et al.  Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain. , 1997, Annual review of neuroscience.

[39]  David J. Anderson,et al.  Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain , 1996, Cell.

[40]  E. Kandel,et al.  Control of Memory Formation Through Regulated Expression of a CaMKII Transgene , 1996, Science.

[41]  R. Klein,et al.  TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. , 1996, Genes & development.

[42]  C. Shatz,et al.  Synaptic Activity and the Construction of Cortical Circuits , 1996, Science.

[43]  T Bonhoeffer,et al.  Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[44]  M. Radeke,et al.  Developmental and mature expression of full‐length and truncated TrkB, receptors in the rat forebrain , 1996, The Journal of comparative neurology.

[45]  M. Barbacid,et al.  Mice Lacking Brain-Derived Neurotrophic Factor Exhibit Visceral Sensory Neuron Losses Distinct from Mice Lacking NT4 and Display a Severe Developmental Deficit in Control of Breathing , 1996, The Journal of Neuroscience.

[46]  S. Dymecki.  Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Ted Abel,et al.  Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice , 1996, Neuron.

[48]  T. Bliss,et al.  Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1 , 1996, Nature.

[49]  C. Henderson.  Role of neurotrophic factors in neuronal development , 1996, Current Opinion in Neurobiology.

[50]  Y. Barde,et al.  Physiology of the neurotrophins. , 1996, Annual review of neuroscience.

[51]  Scott E. Fraser,et al.  Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo , 1995, Nature.

[52]  R. Morris,et al.  Distinct components of spatial learning revealed by prior training and NMDA receptor blockade , 1995, Nature.

[53]  T Bonhoeffer,et al.  Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[54]  A. Davies,et al.  Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons. , 1995, The EMBO journal.

[55]  I. Black,et al.  Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[56]  M. Gallagher,et al.  Entorhinal-perirhinal lesions impair performance of rats on two versions of place learning in the Morris water maze. , 1995, Behavioral neuroscience.

[57]  G. Yancopoulos,et al.  Neurotrophic factors and their receptors , 1994, Annals of neurology.

[58]  M. Barbacid.  Neurotrophic Factors and Their Receptors , 1995, Bio/Technology.

[59]  R. Heumann,et al.  BDNF, and NT‐4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones , 1994, Neuroreport.

[60]  Thomas Rülicke,et al.  Behavioral and anatomical deficits in mice homozygous for a modified β-amyloid precursor protein gene , 1994, Cell.

[61]  Ming Xu,et al.  Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses , 1994, Cell.

[62]  D. Weinberger,et al.  The effects of combined prefrontal cortical and hippocampal damage on dopamine-related behaviors in rats , 1994, Pharmacology Biochemistry and Behavior.

[63]  K. Rajewsky,et al.  Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. , 1994, Science.

[64]  Rudolf Jaenisch,et al.  Mice lacking brain-derived neurotrophic factor develop with sensory deficits , 1994, Nature.

[65]  M. Barbacid,et al.  Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death , 1993, Cell.

[66]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[67]  S. Prusiner,et al.  Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein , 1992, Nature.

[68]  Joseph E LeDoux,et al.  Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. , 1992, Behavioral neuroscience.

[69]  J. D. McGaugh,et al.  Amygdaloid complex lesions differentially affect retention of tasks using appetitive and aversive reinforcement. , 1990, Behavioral neuroscience.

[70]  K Mikoshiba,et al.  The role of myelination in learning performance observed in two strains of myelin-deficient mutant mice (shiverer and mld). , 1988, Behavioral and neural biology.

[71]  B. Hogan,et al.  Manipulating the mouse embryo: A laboratory manual , 1986 .

[72]  R. Morris,et al.  Place navigation impaired in rats with hippocampal lesions , 1982, Nature.

[73]  P. Ropartz,et al.  Responses to novelty and changes in behavior across a 3-week postoperative period in hippocampal-lesioned mice , 1981, Physiology & Behavior.

[74]  R. Passingham.  The hippocampus as a cognitive map J. O'Keefe & L. Nadel, Oxford University Press, Oxford (1978). 570 pp., £25.00 , 1979, Neuroscience.

[75]  L. Nadel,et al.  The Hippocampus as a Cognitive Map , 1978 .

[76]  F. Gage,et al.  Hippocampal connections and spatial discrimination , 1978, Brain Research.

[77]  L. Jarrard.  Anatomical and behavioral analysis of hippocampal cell fields in rats. , 1976, Journal of comparative and physiological psychology.

[78]  G. J. Thomas,et al.  Evaluation of enhanced thigmotaxis as a condition of impaired maze learning by rats with hippocampal lesions. , 1967, Journal of comparative and physiological psychology.