TCR usage, gene expression and function of two distinct FOXP3+Treg subsets within CD4+CD25hi T cells identified by expression of CD39 and CD45RO

[1]  Hiroshi Takayanagi,et al.  Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis , 2013, Nature Medicine.

[2]  Olga V. Britanova,et al.  Preparing Unbiased T-Cell Receptor and Antibody cDNA Libraries for the Deep Next Generation Sequencing Profiling , 2013, Front. Immunol..

[3]  Mikhail Shugay,et al.  MiTCR: software for T-cell receptor sequencing data analysis , 2013, Nature Methods.

[4]  Simon Milling,et al.  Dendritic cells and regulatory T cells in spondyloarthritis , 2013, Current opinion in rheumatology.

[5]  Shimon Sakaguchi,et al.  The plasticity and stability of regulatory T cells , 2013, Nature Reviews Immunology.

[6]  S. Sakaguchi,et al.  Development and maintenance of regulatory T cells. , 2013, Immunity.

[7]  K. Nakai,et al.  T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development. , 2012, Immunity.

[8]  L. Qiang,et al.  Levels of Circulating Th17 Cells and Regulatory T Cells in Ankylosing Spondylitis Patients with an Inadequate Response to Anti−TNF-α Therapy , 2012, Journal of Clinical Immunology.

[9]  A. Rudensky,et al.  Regulatory T cells and Foxp3 , 2011, Immunological reviews.

[10]  Dmitriy A Bolotin,et al.  Quantitative tracking of T cell clones after haematopoietic stem cell transplantation , 2011, EMBO molecular medicine.

[11]  S. Hori.  Stability of regulatory T-cell lineage. , 2011, Advances in immunology.

[12]  A. Rizzo,et al.  Expansion of intestinal CD4+CD25(high) Treg cells in patients with ankylosing spondylitis: a putative role for interleukin-10 in preventing intestinal Th17 response. , 2010, Arthritis and rheumatism.

[13]  J. Buckner.  Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases , 2010, Nature Reviews Immunology.

[14]  L. Cosmi,et al.  CD161 is a marker of all human IL‐17‐producing T‐cell subsets and is induced by RORC , 2010, European journal of immunology.

[15]  R. DePinho,et al.  Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells , 2010, Nature Immunology.

[16]  D. Hafler,et al.  FOXP3+ regulatory T cells in the human immune system , 2010, Nature Reviews Immunology.

[17]  A. Rizzo,et al.  Expansion of Intestinal CD 4 CD 25 high Treg Cells in Patients With Ankylosing Spondylitis A Putative Role for Interleukin-10 in Preventing Intestinal Th 17 Response , 2010 .

[18]  N. Tubridy,et al.  CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis1 , 2009, The Journal of Immunology.

[19]  J. Bluestone,et al.  Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo , 2009, Nature Immunology.

[20]  T. Nomura,et al.  Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. , 2009, Immunity.

[21]  Y. Jong,et al.  Altered homeostasis of CD4+ FoxP3+ regulatory T‐cell subpopulations in systemic lupus erythematosus , 2009, Immunology.

[22]  C. Weaver,et al.  Diversity in the contribution of interleukin‐10 to T‐cell‐mediated immune regulation , 2008, Immunological reviews.

[23]  T. Nomura,et al.  Regulatory T Cells and Immune Tolerance , 2008, Cell.

[24]  P. Rossini,et al.  Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. , 2007, Blood.

[25]  M. Roncarolo,et al.  Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. , 2007, International immunology.

[26]  R. Steinman,et al.  Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice , 2007, The Journal of experimental medicine.

[27]  T. Huizinga,et al.  Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells , 2007, European journal of immunology.

[28]  R. Andreesen,et al.  Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion. , 2006, Blood.

[29]  M. Probst-Kepper,et al.  Signatures of human regulatory T cells: an encounter with old friends and new players , 2006, Genome Biology.

[30]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[31]  Terence P. Speed,et al.  A comparison of normalization methods for high density oligonucleotide array data based on variance and bias , 2003, Bioinform..