Prior‐knowledge treatment planning for volumetric arc therapy using feature‐based database mining

Treatment planning for volumetric arc therapy (VMAT) is a lengthy process that requires many rounds of optimizations to obtain the best treatment settings and optimization constraints for a given patient's geometry. We propose a feature‐selection search engine that explores previously treated cases of similar anatomy, returning the optimal plan configurations and attainable DVH constraints. Using an institutional database of 83 previously treated cases of prostate carcinoma treated with volumetric‐modulated arc therapy, the search procedure first finds the optimal isocenter position with an optimization procedure, then ranks the anatomical similarity as the mean distance between targets. For the best matching plan, the planning information is reformatted to the DICOM format and imported into the treatment planning system to suggest isocenter, arc directions, MLC patterns, and optimization constraints that can be used as starting points in the optimization process. The approach was tested to create prospective treatment plans based on anatomical features that match previously treated cases from the institution database. By starting from a near‐optimal solution and using previous optimization constraints, the best matching test only required simple optimization steps to further decrease target inhomogeneity, ultimately reducing time spend by the therapist in planning arcs' directions and lengths. PACS number: 87.55.D‐, 87.55.de

[1]  Lei Xing,et al.  Quantitation of the a priori dosimetric capabilities of spatial points in inverse planning and its significant implication in defining IMRT solution space , 2005, Physics in medicine and biology.

[2]  Fang-Fang Yin,et al.  A planning quality evaluation tool for prostate adaptive IMRT based on machine learning. , 2011, Medical physics.

[3]  Steve Webb,et al.  Elimination of importance factors for clinically accurate selection of beam orientations, beam weights and wedge angles in conformal radiation therapy. , 2003, Medical physics.

[4]  Russell H. Taylor,et al.  Patient geometry-driven information retrieval for IMRT treatment plan quality control. , 2009, Medical physics.

[5]  L. Xing,et al.  Incorporating prior knowledge into beam orientation optimization in IMRT. , 2002, International journal of radiation oncology, biology, physics.

[6]  L. Xing,et al.  Dose-volume based ranking of incident beam direction and its utility in facilitating IMRT beam placement. , 2004, International journal of radiation oncology, biology, physics.

[7]  Lei Xing,et al.  Clinical knowledge-based inverse treatment planning. , 2004, Physics in medicine and biology.

[8]  C G Rowbottom,et al.  Simultaneous optimization of beam orientations and beam weights in conformal radiotherapy. , 2001, Medical physics.

[9]  Michael Lahanas,et al.  A geometry based optimization algorithm for conformal external beam radiotherapy. , 2003, Physics in medicine and biology.

[10]  C G Rowbottom,et al.  Improvements in prostate radiotherapy from the customization of beam directions. , 1998, Medical physics.

[11]  Yan Yu,et al.  Multi-objective optimization in radiotherapy: applications to stereotactic radiosurgery and prostate brachytherapy , 2000, Artif. Intell. Medicine.

[12]  D Baltas,et al.  A multiobjective gradient-based dose optimization algorithm for external beam conformal radiotherapy. , 2001, Physics in medicine and biology.

[13]  A Pugachev,et al.  Computer-assisted selection of coplanar beam orientations in intensity-modulated radiation therapy. , 2001, Physics in medicine and biology.

[14]  Radhe Mohan,et al.  Algorithm and performance of a clinical IMRT beam-angle optimization system. , 2003, Physics in medicine and biology.

[15]  L. Xing,et al.  Pseudo beam's-eye-view as applied to beam orientation selection in intensity-modulated radiation therapy. , 2001, International journal of radiation oncology, biology, physics.

[16]  Russell H. Taylor,et al.  Data-driven approach to generating achievable dose-volume histogram objectives in intensity-modulated radiotherapy planning. , 2011, International journal of radiation oncology, biology, physics.