Surgeon Preference for Endothelial Keratoplasty Techniques.

PURPOSE To examine barriers and facilitators to adoption of Descemet membrane endothelial keratoplasty (DMEK) for treatment of endothelial dysfunction. METHODS Anonymous electronic surveys were emailed to surgeons ordering corneal transplant tissue in the past 18 months from 2 eye banks in the United States (US). RESULTS Of 365 surgeons emailed, 118 (32%) completed the survey. Most respondents were located at an urban site (59%), were in private practice (64%), and had been in practice for >10 years (53%). Participants performing DMEK (n = 70) were more likely to have been in practice for ≤10 years than those not performing DMEK (56% vs. 35%, respectively, P = 0.03). Among respondents not performing DMEK (n = 48, 41%), the most frequently reported barriers were technical difficulty (n = 30, 63%), a lack of experience (n = 29, 60%), low surgical volume (n = 20, 42%), and risk of postoperative complications (n = 19, 40%). Most (n = 46, 96%) respondents not performing DMEK were interested in doing so, with the following reported as helpful resources: wet laboratory courses (n = 35, 73%), eye bank-prepared tissue: preloaded/prestripped (n = 32, 67%), back-up tissue in case of inadvertent graft damage (n = 29, 60%), higher surgical volume to support the learning curve (n = 28, 58%), and surgical mentorship (n = 22, 46%). Only a minority wanted more data to highlight superiority over other EK procedures (n = 12, 25%). CONCLUSIONS There is substantial interest in learning to perform DMEK among the surgical community. Barriers identified in this survey may be addressed to help surgeons increase DMEK adoption.

[1]  S. Mian,et al.  Update on Descemet membrane endothelial keratoplasty. , 2019, Current opinion in ophthalmology.

[2]  J. Rose-Nussbaumer,et al.  Corneal Higher-Order Aberrations in Descemet Membrane Endothelial Keratoplasty versus Ultrathin DSAEK in the Descemet Endothelial Thickness Comparison Trial: A Randomized Clinical Trial. , 2019, Ophthalmology.

[3]  F. Price,et al.  Will Level I Evidence Trigger a Tipping Point in Endothelial Keratoplasty? , 2019, Ophthalmology (Rochester, Minn.).

[4]  J. Rose-Nussbaumer,et al.  Descemet Endothelial Thickness Comparison Trial: A Randomized Trial Comparing Ultrathin Descemet Stripping Automated Endothelial Keratoplasty with Descemet Membrane Endothelial Keratoplasty. , 2019, Ophthalmology.

[5]  S. Ferrari,et al.  Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty Grafts With Endothelium Tri-Folded Inwards. , 2018, American journal of ophthalmology.

[6]  David A. Price,et al.  Five-Year Graft Survival of Descemet Membrane Endothelial Keratoplasty (EK) versus Descemet Stripping EK and the Effect of Donor Sex Matching. , 2018, Ophthalmology.

[7]  Anthony N Kuo,et al.  Descemet Membrane Endothelial Keratoplasty: Safety and Outcomes: A Report by the American Academy of Ophthalmology. , 2017, Ophthalmology.

[8]  Yi Zha,et al.  Descemet stripping automated endothelial keratoplasty versus descemet membrane endothelial keratoplasty: a meta-analysis , 2018, International Ophthalmology.

[9]  V. Jhanji,et al.  Learning DMEK From YouTube , 2017, Cornea.

[10]  S. Ferrari,et al.  Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty , 2017, British Journal of Ophthalmology.

[11]  D. Gatinel,et al.  Impact of Surgical Learning Curve in Descemet Membrane Endothelial Keratoplasty on Visual Acuity Gain , 2017, Cornea.

[12]  J. Rose-Nussbaumer,et al.  Survey of Experts on Current Endothelial Keratoplasty Techniques , 2016, Journal of clinical & experimental ophthalmology.

[13]  Z. M. Mayko,et al.  The First 100 Eyes of Standardized Descemet Stripping Automated Endothelial Keratoplasty versus Standardized Descemet Membrane Endothelial Keratoplasty. , 2015, Ophthalmology.

[14]  F. Price,et al.  Evolution of Endothelial Keratoplasty , 2013, Cornea.

[15]  Claus Cursiefen,et al.  Descemet stripping endothelial keratoplasty--rapid recovery of visual acuity. , 2013, Deutsches Arzteblatt international.

[16]  J. Mehta,et al.  Deep Anterior Lamellar Keratoplasty: Surgical Techniques, Challenges, and Management of Intraoperative Complications , 2013, International ophthalmology clinics.

[17]  M. Terry Endothelial keratoplasty: why aren't we all doing Descemet membrane endothelial keratoplasty? , 2012, Cornea.

[18]  Frederico P. Guerra,et al.  Endothelial Keratoplasty: Fellow Eyes Comparison of Descemet Stripping Automated Endothelial Keratoplasty and Descemet Membrane Endothelial Keratoplasty , 2011, Cornea.

[19]  F. Price,et al.  Descemet's membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival. , 2009, Ophthalmology.

[20]  M. Terry,et al.  Descemet-Stripping Automated Endothelial Keratoplasty: Six-month Results in a Prospective Study of 100 Eyes , 2008, Cornea.

[21]  M. Terry,et al.  Endothelial cell loss after Descemet's stripping endothelial keratoplasty in a large prospective series. , 2008, Ophthalmology.

[22]  M. B. Goren The Eye Bank Association of America. , 2006, Comprehensive ophthalmology update.