Developmental noise, ageing and cancer

[1]  C. Waddington.  Canalization of Development and the Inheritance of Acquired Characters , 1942, Nature.

[2]  L. Getz.  A Population Study of the Vole, Microtus pennsylvanicus , 1960 .

[3]  D. Smithers.  A CLINICAL PROSPECT OF THE CANCER PROBLEM , 1960, The Ulster Medical Journal.

[4]  Bernard L. Strehler,et al.  Time, cells, and aging , 1962 .

[5]  Marvin Zelen,et al.  Mathematical Theory of Reliability , 1965 .

[6]  J. Ferlay,et al.  Cancer Incidence in Five Continents , 1970, Union Internationale Contre Le Cancer / International Union against Cancer.

[7]  Alexander William Francis Banfield,et al.  The Mammals of Canada , 1975 .

[8]  K. Illmensee,et al.  Normal genetically mosaic mice produced from malignant teratocarcinoma cells. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[9]  A. Griffiths.  Introduction to Genetic Analysis , 1976 .

[10]  F. Mitelman,et al.  Chromosomes and cancer , 2009 .

[11]  N. Breslow,et al.  Latent carcinoma of prostate at autopsy in seven areas. Collaborative study organized by the International Agency for Research on Cancer, Lyons, France , 1977, International journal of cancer.

[12]  G. Jones,et al.  Factors involved in the high incidence of prostatic cancer among American blacks. , 1981, Progress in clinical and biological research.

[13]  R. Weindruch,et al.  Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. , 1982, Science.

[14]  J. A. Chapman,et al.  Wild mammals of North America: biology, management, and economics , 1983 .

[15]  Robert A. Weinberg,et al.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.

[16]  I. MartínezMartínez.  Epidemiology of Cancer , 1984 .

[17]  E. Rubenstein,et al.  Scientific American Medicine , 1985 .

[18]  P Skehan.  On the normality of growth dynamics of neoplasms in vivo: a data base analysis. , 1986, Growth.

[19]  R. Weindruch,et al.  The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. , 1986, The Journal of nutrition.

[20]  L. M. Franks,et al.  Introduction to the cellular and molecular biology of cancer , 1986 .

[21]  H. Lodish.  Molecular Cell Biology , 1986 .

[22]  M. Retsky,et al.  Prospective computerized simulation of breast cancer: comparison of computer predictions with nine sets of biological and clinical data. , 1987, Cancer research.

[23]  Richard Weindruch,et al.  The Retardation of Aging and Disease by Dietary Restriction , 1988 .

[24]  M Gyllenberg,et al.  Quiescence as an explanation of Gompertzian tumor growth. , 1989, Growth, development, and aging : GDA.

[25]  Caleb E. Finch,et al.  Longevity, senescence, and the genome , 1990 .

[26]  M. Retsky,et al.  Is Gompertzian or exponential kinetics a valid description of individual human cancer growth? , 1990, Medical hypotheses.

[27]  H. Tulinius.  Latent malignancies at autopsy: a little used source of information on cancer biology. , 1991, IARC scientific publications.

[28]  L. Donehower,et al.  Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours , 1992, Nature.

[29]  R. Weindruch.  Effect of caloric restriction on age-associated cancers , 1992, Experimental Gerontology.

[30]  J. Vaupel,et al.  Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster. , 1992, Science.

[31]  F. Bronson,et al.  Life History AND BIOECONOMY OF THE House Mouse , 1992, Biological reviews of the Cambridge Philosophical Society.

[32]  G. Haas,et al.  The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients. , 1993, The Journal of urology.

[33]  M. Montenarh,et al.  Overexpression of wild-type p53 interferes with normal development in Xenopus laevis embryos. , 1994, Oncogene.

[34]  R. Weinberg,et al.  Tumor spectrum analysis in p53-mutant mice , 1994, Current Biology.

[35]  DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. , 1994, Molecular and cellular biology.

[36]  M. Kaufman,et al.  High-frequency developmental abnormalities in p53-deficient mice , 1995, Current Biology.

[37]  P. G. Wells,et al.  A teratologic suppressor role for p53 in benzo(a)pyrene–treated transgenic p53-deficient mice , 1995, Nature Genetics.

[38]  T. Nakamura,et al.  An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[39]  T. Jacks,et al.  A subset of p53-deficient embryos exhibit exencephaly , 1995, Nature Genetics.

[40]  Guillermina Lozano,et al.  Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 , 1995, Nature.

[41]  Lawrence A. Donehower,et al.  Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 , 1995, Nature.

[42]  M. Katsuki,et al.  p53-dependent apoptosis suppresses radiation–induced teratogenesis , 1996, Nature Medicine.

[43]  V. Rotter,et al.  p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells , 1996, Molecular and cellular biology.

[44]  K. Kosik,et al.  Accelerated neuronal differentiation induced by p53 suppression. , 1996, Journal of cell science.

[45]  G. Cooper.  The Cell: A Molecular Approach , 1996 .

[46]  H. Varmus,et al.  Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys. , 1996, Genes & development.

[47]  D. Lane,et al.  Tumour suppressors: A developing role for p53? , 1997, Current Biology.

[48]  J. Wallingford,et al.  P53 activity is essential for normal development in Xenopus , 1997, Current Biology.

[49]  S. Lindquist,et al.  Hsp90 as a capacitor for morphological evolution , 1998, Nature.

[50]  P. Gariglio,et al.  p53 is a rate-limiting factor in the repair of higher-order DNA structure. , 1999, Biochimica et biophysica acta.

[51]  P. Duesberg,et al.  How aneuploidy affects metabolic control and causes cancer. , 1999, The Biochemical journal.

[52]  M. Mangel,et al.  Messages from mortality: the evolution of death rates in the old. , 1999, Trends in ecology & evolution.

[53]  M. White,et al.  Absence of cancer–associated changes in human fibroblasts immortalized with telomerase , 1999, Nature Genetics.

[54]  C. Prives,et al.  The p53 pathway , 1999, The Journal of pathology.

[55]  Rowe Jw,et al.  The future of aging. , 1999 .

[56]  Robert A. Weinberg,et al.  Creation of human tumour cells with defined genetic elements , 1999, Nature.

[57]  S. Rattan.  Biogerontology: The Next Step , 2000, Annals of the New York Academy of Sciences.

[58]  Rachel L. Allen,et al.  Defying death after DNA damage , 2000, Nature.

[59]  Steven N. Austad,et al.  Why do we age? , 2000, Nature.

[60]  Ronald A. DePinho,et al.  The age of cancer , 2000, Nature.

[61]  J. Kaprio,et al.  Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. , 2000, The New England journal of medicine.

[62]  L. Guarente,et al.  Genetic pathways that regulate ageing in model organisms , 2000, Nature.

[63]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[64]  K. Vousden,et al.  Minireviewp 53 : Death Star able to induce the defensive p 53 response to oncogene , 2000 .

[65]  Ash A. Alizadeh,et al.  Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling , 2000, Nature.

[66]  Caleb E. Finch,et al.  Chance, development, and aging , 2000 .

[67]  Leonard Hayflick,et al.  The future of ageing , 2000, Nature.

[68]  T. Kirkwood,et al.  CALORIE RESTRICTION AND AGING: A LIFE‐HISTORY ANALYSIS , 2000, Evolution; international journal of organic evolution.

[69]  J. D. Weber,et al.  The ARF/p53 pathway. , 2000, Current opinion in genetics & development.

[70]  W. Hahn,et al.  Derivation of human tumor cells in vitro without widespread genomic instability. , 2001, Cancer research.

[71]  D. Woods,et al.  Regulation of p53 function. , 2001, Experimental cell research.

[72]  L. Gavrilov,et al.  The reliability theory of aging and longevity. , 2001, Journal of theoretical biology.

[73]  The marks, mechanisms and memory of epigenetic states in mammals. , 2001 .

[74]  A. Aranda-Anzaldo.  Cancer Development and Progression: A Non-Adaptive Process Driven by Genetic Drift , 2001, Acta biotheoretica.

[75]  H. Fernández,et al.  Alzheimer movement re-examined 25 years later: is it a "disease" or a senile condition in medical nature? , 2001, Frontiers in bioscience : a journal and virtual library.

[76]  Jian-Hua Luo.  Gene expression alterations in human prostate cancer. , 2002, Drugs of today.

[77]  L. Donehower.  Does p53 affect organismal aging? , 2002, Journal of cellular physiology.

[78]  K. Helin,et al.  Mdm4 (Mdmx) Regulates p53-Induced Growth Arrest and Neuronal Cell Death during Early Embryonic Mouse Development , 2002, Molecular and Cellular Biology.

[79]  D. Reznick,et al.  The evolution of senescence in fish , 2002, Mechanisms of Ageing and Development.

[80]  M. Loeken,et al.  Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis. , 2002, Genes & development.

[81]  D. Hall,et al.  Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans , 2002, Nature.

[82]  J. Vijg,et al.  Age-related mutation accumulation at a lacZ reporter locus in normal and tumor tissues of Trp53-deficient mice. , 2002, Mutation research.

[83]  S. Lindquist,et al.  Hsp90 as a capacitor of phenotypic variation , 2002, Nature.

[84]  Towards a morphogenetic perspective on cancer. , 2002, Rivista di biologia.

[85]  Peter H Gann,et al.  Overdiagnosis due to prostate-specific antigen screening: lessons from U.S. prostate cancer incidence trends. , 2002, Journal of the National Cancer Institute.

[86]  G. Fink,et al.  Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration , 2002, Nature.

[87]  G. Hannon,et al.  Transformation of normal human cells in the absence of telomerase activation. , 2002, Cancer cell.

[88]  F. McKeon,et al.  Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans. , 2002, Trends in molecular medicine.

[89]  K. Hemminki,et al.  Cancer risks in twins: Results from the Swedish family‐cancer database , 2002, International journal of cancer.

[90]  J. Wilmoth,et al.  The Cancer Transition in Japan since 1951 , 2002 .

[91]  Jan Vijg,et al.  Large genome rearrangements as a primary cause of aging , 2002, Mechanisms of Ageing and Development.

[92]  P. Klatt,et al.  'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally , 2002, The EMBO journal.

[93]  A. Aranda-Anzaldo.  Understanding cancer as a formless phenomenon. , 2002, Medical hypotheses.

[94]  D. Dunson,et al.  Mutational fingerprints of aging. , 2002, Nucleic acids research.

[95]  Leonid A. Gavrilov,et al.  Evolutionary Theories of Aging and Longevity , 2002, TheScientificWorldJournal.

[96]  The 'reservoir' of undetected bronchial carcinomas in the general population. , 2002, Lung cancer.

[97]  C. Perou,et al.  Molecular portraits and the family tree of cancer , 2002, Nature Genetics.

[98]  Stephen N. Jones,et al.  p53 mutant mice that display early ageing-associated phenotypes , 2002, Nature.

[99]  H. Frierson,et al.  Classifying human cancer by analysis of gene expression. , 2003, Trends in molecular medicine.

[100]  A. Macieira-Coelho.  Neoplastic disease through the human life span , 2004, Biogerontology.