Preparation of multicompartment lipid-based systems based on vesicle interactions.

Various strategies for constructing artificial multicompartment vesicular systems, which primitively mimic the structure of eukaryotic cells, are presented. These model systems are appropriate for addressing several issues such as the understanding of cell processes, the development of nanoreactors and novel multicompartment delivery systems for specific drug applications, the transport through bilayer membranes, and also hypothesizing on the evolution of eukaryotic cells as originating from the symbiotic association of prokaryotes.

[1]  P. Ahl,et al.  Interdigitation-fusion: a new method for producing lipid vesicles of high internal volume. , 1994, Biochimica et biophysica acta.

[2]  Pasquale Stano,et al.  Giant Vesicles: Preparations and Applications , 2010, Chembiochem : a European journal of chemical biology.

[3]  Joseph A. Zasadzinski,et al.  Encapsulation of bilayer vesicles by self-assembly , 1997, nature.

[4]  Jan C M van Hest,et al.  Synthetic cells and organelles: compartmentalization strategies , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

[5]  W. Martin,et al.  Eukaryotic evolution, changes and challenges , 2006, Nature.

[6]  Kostas Kostarelos,et al.  Construction of nanoscale multicompartment liposomes for combinatory drug delivery. , 2007, International journal of pharmaceutics.

[7]  W. Martin,et al.  Evolutionary origins of metabolic compartmentalization in eukaryotes , 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

[8]  Natalie Forbes,et al.  Novel Methods of Enhanced Retention in and Rapid, Targeted Release from Liposomes. , 2011, Current opinion in colloid & interface science.

[9]  O. Orwar,et al.  Chapter 15 - Complex nanotube-liposome networks. , 2009, Methods in enzymology.

[10]  Y. Okumura,et al.  Giant vesicles with membranous microcompartments. , 2011, Langmuir : the ACS journal of surfaces and colloids.

[11]  K. Edwards,et al.  Liposomes, disks, and spherical micelles: aggregate structure in mixtures of gel phase phosphatidylcholines and poly(ethylene glycol)-phospholipids. , 2003, Biophysical journal.

[12]  M. Maurel,et al.  Origins of Life: Self-Organization and/or Biological Evolution? , 2009 .

[13]  D. Tsiourvas,et al.  Interaction between complementary liposomes: a process leading to multicompartment systems formation , 2006, Journal of molecular recognition : JMR.

[14]  D. Deamer,et al.  Self-assembling amphiphilic molecules: Synthesis in simulated interstellar/precometary ices. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[15]  Z. Sideratou,et al.  Complementary liposomes based on phosphatidylcholine: interaction effectiveness vs protective coating. , 2002, Journal of colloid and interface science.

[16]  D. Deamer,et al.  Synthesis of phospholipids and membranes in prebiotic conditions , 1977, Nature.

[17]  Johannes A A W Elemans,et al.  Self-assembled nanoreactors. , 2005, Chemical reviews.

[18]  M. Bally,et al.  Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine. , 1998, Biochimica et biophysica acta.

[19]  D. Deamer,et al.  On the origin of systems , 2009, EMBO reports.

[20]  R. Hengeveld,et al.  Causes and Consequences of Eukaryotization Through Mutualistic Endosymbiosis and Compartmentalization , 2004, Acta biotheoretica.

[21]  B. Lentz,et al.  Polymer-induced membrane fusion: potential mechanism and relation to cell fusion events. , 1994, Chemistry and physics of lipids.

[22]  L. Margulis Symbiosis in cell evolution: Life and its environment on the early earth , 1981 .

[23]  Z. Sideratou,et al.  Structural features of interacting complementary liposomes promoting formation of multicompartment structures. , 2009, Chemphyschem : a European journal of chemical physics and physical chemistry.

[24]  D. Deamer,et al.  Role of lipids in prebiotic structures. , 1980, Bio Systems.

[25]  Fredric M. Menger,et al.  Giant Vesicles: Imitating the Cytological Processes of Cell Membranes , 1998 .

[26]  A. Lazcano Complexity, self-organization and the origin of life: The happy liaison? , 2009 .

[27]  Constantinos M Paleos,et al.  Interaction of Vesicles: Adhesion, Fusion and Multicompartment Systems Formation , 2011, Chembiochem : a European journal of chemical biology.

[28]  Kasper Renggli,et al.  Selective and Responsive Nanoreactors , 2011 .

[29]  J. Zasadzinski,et al.  Encapsulating vesicles and colloids from cochleate cylinders , 2003 .

[30]  P. Luisi,et al.  Lipid vesicles as possible intermediates in the origin of life , 1999 .

[31]  Z. Sideratou,et al.  Interactions of complementary PEGylated liposomes and characterization of the resulting aggregates. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[32]  Eugene V. Koonin,et al.  Introns and the origin of nucleus–cytosol compartmentalization , 2006, Nature.

[33]  J. Noveron,et al.  Energy Transduction Inside of Amphiphilic Vesicles: Encapsulation of Photochemically Active Semiconducting Particles , 2009, Origins of Life and Evolution of Biospheres.

[34]  J. M. Sanderson,et al.  Selective adhesion, lipid exchange and membrane-fusion processes between vesicles of various sizes bearing complementary molecular recognition groups. , 2001, Chemphyschem : a European journal of chemical physics and physical chemistry.

[35]  M. Winterhalter,et al.  Polymer induced fusion and leakage of small unilamellar phospholipid vesicles: effect of surface grafted polyethylene-glycol in the presence of free PEG , 1997 .

[36]  J. Zasadzinski,et al.  Multiple lipid compartments slow vesicle contents release in lipases and serum. , 2007, ACS nano.

[37]  D. Penny,et al.  Evaluating hypotheses for the origin of eukaryotes. , 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.

[38]  D. Deamer,et al.  The Lipid World , 2001, Origins of life and evolution of the biosphere.

[39]  D. Needham,et al.  The "Stealth" Liposome: A Prototypical Biomaterial , 1995 .

[40]  D. Deamer,et al.  Membrane self‐assembly processes: Steps toward the first cellular life , 2002, The Anatomical record.

[41]  O. G. Mouritsen,et al.  Screening effect of PEG on avidin binding to liposome surface receptors. , 2001, International journal of pharmaceutics.

[42]  W. Martin,et al.  The energetics of genome complexity , 2010, Nature.

[43]  Kyoung Taek Kim,et al.  Smart nanocontainers and nanoreactors. , 2010, Nanoscale.

[44]  F. Menger,et al.  Cytomimetic Organic Chemistry: Early Developments , 1995 .

[45]  J. Israelachvili,et al.  Use of poly(ethylene glycol) to control cell aggregation and fusion , 1999 .

[46]  P. Ahl,et al.  Interdigitation--fusion liposomes. , 2003, Methods in enzymology.

[47]  Needham,et al.  PEG-covered lipid surfaces: bilayers and monolayers. , 2000, Colloids and surfaces. B, Biointerfaces.

[48]  P. Walde,et al.  Building artificial cells and protocell models: experimental approaches with lipid vesicles. , 2010, BioEssays : news and reviews in molecular, cellular and developmental biology.

[49]  Joseph A. Zasadzinski,et al.  Nanocompartments Enclosing Vesicles, Colloids, and Macromolecules via Interdigitated Lipid Bilayers , 2002 .

[50]  C A Evans,et al.  The vesosome-- a multicompartment drug delivery vehicle. , 2004, Current medicinal chemistry.

[51]  C. M. Paleos,et al.  Guanidinium group: a versatile moiety inducing transport and multicompartmentalization in complementary membranes. , 2008, Biochimica et biophysica acta.