Only some spatial patterns of fMRI response are read out in task performance

Classification methods show that the spatial pattern of a functional magnetic resonance imaging response across the cortex contains category information, but whether such patterns are used, or 'read out', in behavioral performance remains untested. We show that although the spatial pattern in both the retinotopic and lateral occipital cortex (LOC) in humans contains category information, only in the LOC is the pattern stronger for correct than for incorrect trials. Thus, some, but not all, spatial patterns are read out during task performance.

[1]  K. Grill-Spector,et al.  The dynamics of object-selective activation correlate with recognition performance in humans , 2000, Nature Neuroscience.

[2]  M. Bar,et al.  Cortical Mechanisms Specific to Explicit Visual Object Recognition , 2001, Neuron.

[3]  A. Ishai,et al.  Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal Cortex , 2001, Science.

[4]  David D. Cox,et al.  Functional magnetic resonance imaging (fMRI) “brain reading”: detecting and classifying distributed patterns of fMRI activity in human visual cortex , 2003, NeuroImage.

[5]  N. Kanwisher,et al.  The fusiform face area subserves face perception, not generic within-category identification , 2004, Nature Neuroscience.

[6]  W. Newsome,et al.  What electrical microstimulation has revealed about the neural basis of cognition , 2004, Current Opinion in Neurobiology.

[7]  F. Tong,et al.  Decoding the visual and subjective contents of the human brain , 2005, Nature Neuroscience.

[8]  R. Gur,et al.  Telling truth from lie in individual subjects with fast event‐related fMRI , 2005, Human brain mapping.

[9]  G. Rees,et al.  Predicting the orientation of invisible stimuli from activity in human primary visual cortex , 2005, Nature Neuroscience.

[10]  J. Mattingley,et al.  Neurodisruption of selective attention: insights and implications , 2005, Trends in Cognitive Sciences.

[11]  N. Kanwisher,et al.  Discrimination Training Alters Object Representations in Human Extrastriate Cortex , 2006, The Journal of Neuroscience.

[12]  R. Kiani,et al.  Microstimulation of inferotemporal cortex influences face categorization , 2006, Nature.

[13]  Rainer Goebel,et al.  Information-based functional brain mapping. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[14]  F. Tong,et al.  Decoding Seen and Attended Motion Directions from Activity in the Human Visual Cortex , 2006, Current Biology.

[15]  J. O'Doherty,et al.  Decoding the neural substrates of reward-related decision making with functional MRI , 2007, Proceedings of the National Academy of Sciences.

[16]  R. Rosenfeld Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.