Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs.

[1]  C. Mcginn,et al.  Recent advances in the use of radiosensitizing nucleosides. , 2001, Seminars in radiation oncology.

[2]  M. Comalada,et al.  Macrophages require different nucleoside transport systems for proliferation and activation , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  C. Macleod,et al.  Lipopolysaccharide-induced Apoptosis of Macrophages Determines the Up-regulation of Concentrative Nucleoside Transporters Cnt1 and Cnt2 through Tumor Necrosis Factor-α-dependent and -independent Mechanisms* , 2001, The Journal of Biological Chemistry.

[4]  J. Cassidy,et al.  The evolution of fluoropyrimidine therapy: from intravenous to oral. , 2001, The oncologist.

[5]  J. Lloberas,et al.  Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug. , 2001, Molecular pharmacology.

[6]  A Felipe,et al.  Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver. , 2001, Journal of hepatology.

[7]  J. Garcia-Manteiga,et al.  Complex regulation of nucleoside transporter expression in epithelial and immune system cells , 2001, Molecular membrane biology.

[8]  A. Felipe,et al.  Nutritional regulation of nucleoside transporter expression in rat small intestine. , 2000, Gastroenterology.

[9]  M. Pastor-Anglada,et al.  Electrogenic uptake of nucleosides and nucleoside‐derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes , 2000, FEBS letters.

[10]  D. Loo,et al.  Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes. , 2000, Drug metabolism and disposition: the biological fate of chemicals.

[11]  Y. Dragan,et al.  Selective loss of nucleoside carrier expression in rat hepatocarcinomas , 2000, Hepatology.

[12]  J. Mackey,et al.  Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. , 1999, Journal of the National Cancer Institute.

[13]  J. Mackey,et al.  Nucleoside transporters: molecular biology and implications for therapeutic development. , 1999, Molecular medicine today.

[14]  T. Krude.  Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner. , 1999, Experimental cell research.

[15]  A. Felipe,et al.  Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells , 1998, Hepatology.

[16]  A. Felipe,et al.  Transport and mode of action of nucleoside derivatives used in chemical and antiviral therapies. , 1998, Trends in pharmacological sciences.

[17]  J. Lloberas,et al.  Na+-dependent nucleoside transport in liver: two different isoforms from the same gene family are expressed in liver cells. , 1998, The Biochemical journal.

[18]  K. Giacomini,et al.  Functional and Molecular Characteristics of Na+-dependent Nucleoside Transporters , 1997, Pharmaceutical Research.

[19]  B. Anachkova,et al.  Effect of mimosine on DNA synthesis in mammalian cells. , 1997, Cancer research.

[20]  D. Hedley,et al.  Modulation of the equilibrative nucleoside transporter by inhibitors of DNA synthesis. , 1995, British Journal of Cancer.

[21]  D. Hedley,et al.  Effects of thymidylate synthase inhibition on thymidine kinase activity and nucleoside transporter expression. , 1995, Cancer research.

[22]  J. Hamlin,et al.  A general protocol for evaluating the specific effects of DNA replication inhibitors. , 1993, Nucleic acids research.

[23]  C. Enrich,et al.  Early induction of Na+‐dependent uridine uptake in the regenerating rat liver , 1993, FEBS letters.

[24]  P. Dijkwel,et al.  The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells , 1992, Molecular and cellular biology.

[25]  M. Lalande,et al.  A reversible arrest point in the late G1 phase of the mammalian cell cycle. , 1990, Experimental cell research.

[26]  S. Baldwin,et al.  Recent advances in the molecular biology and physiology of nucleoside and nucleobase transporters , 2001 .

[27]  A. Felipe,et al.  Nucleoside transporters and liver cell growth. , 1998, Biochemistry and cell biology = Biochimie et biologie cellulaire.