Joint toxicity of mixtures of 8 and 24 chemicals to the guppy (Poecilia reticulata).

Abstract The acute median lethal concentrations of equitoxic mixtures of 8 and 24 toxicants with diverse modes of action to guppies were determined. To quantify the joint toxicity, the results are expressed by means of the Mixture Toxicity Index (MTI). The toxicity of the mixtures was near concentration addition. Concentrations of the chemicals of about 0.1 of their LC50's contributed to the toxicity of the mixtures.

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