The flicker electroretinogram of the human eye.

Summary. An account is given of the human photopic flicker electroretinogram (ERG) with increasing flicker frequency, and its different phases are analyzed. With rising frequency, the amplitude initially diminishes owing to interference between the negative a-wave and the 2nd positive off-effect making the ERG practically diphasic. With a further increase in flicker frequency, a considerably greater amplitude of response is recorded, owing to superimposition of the off-effect on the b-wave. This is followed by a linear decrease in amplitude until fusion occurs. Slightly before fusion, the flicker ERG consists of an a-wave and the 1st off-effect. The flicker fusion frequency is directly proportional to the logarithm of light intensity (Ferry-Porter law) up to 90-95 flashes/sec. With an increase in light intensity above 2,500 lux, the flicker fusion frequency once more diminishes. The different phases in the flicker ERG are discussed. It is suggested that the splitting of the b-wave and the off-effect can be explained by the presence of colour components with different latency periods.

[1]  W. R. Biersdorf,et al.  Flicker and color adaptation in the human electroretinogram. , 1956, Journal of the Optical Society of America.

[2]  E. Dodt.  Generalized inhibition of the retinal ganglion cells in relation to wavelength and state of adaptation. , 1956, Acta physiologica Scandinavica.

[3]  Adrian.  Receptors and Sensory Perception , 1955, Nature.

[4]  M. Goto,et al.  Some mechanisms of color reception found by analysing the electroretinogram of frog. II. Crest times of off-responses as a function of wave-length of light. , 1954, The Japanese journal of physiology.

[5]  M. Goto,et al.  Some mechanisms of color reception found by analyzing the electroretinogram of frog. I. Color characteristics of the multiple off-response and number of retinal elements. , 1954, The Japanese journal of physiology.

[6]  M. Goto,et al.  On the splitting of off-response in electroretinogram. , 1954, The Japanese journal of physiology.

[7]  E. Dodt,et al.  THE USE OF FLICKER ELECTRORETINOGRAPHY IN THE HUMAN EYE , 1954, Acta ophthalmologica.

[8]  G. Schubert,et al.  Beitrag zur Analyse des menschlichen Elektroretinogramms , 1952 .

[9]  E. Dodt,et al.  Cone Electroretinography by Flicker , 1951, Nature.

[10]  K. Motokawa.  Selective inhibitory action of colored light upon the retinal color processes and its usefulness for analysis of the mechanism of color reception. , 1950, The Tohoku journal of experimental medicine.

[11]  James E. Lebensohn,et al.  Sensory Mechanisms of the Retina , 1947 .

[12]  E. Adrian.  The electric response of the human eye , 1945, The Journal of physiology.

[13]  R. Granit,et al.  The electrical responses of dark‐adapted frogs' eyes to monochromatic stimuli , 1937, The Journal of physiology.

[14]  S. Hecht,et al.  INTERMITTENT STIMULATION BY LIGHT : II. THE MEASUREMENT OF CRITICAL FUSION FREQUENCY FOR THE HUMAN EYE. , 1933 .

[15]  E. S. Ferry.  Persistence of vision , 1892, American Journal of Science.

[16]  Max Johann Sigismund Schultze,et al.  Zur Anatomie und Physiologie der Retina , 1866 .