Sexing the Cranium from the Foramen Magnum Using Discriminant Analysis in a Brazilian Sample.

In the identification process, the foramen magnum has shown controversial results in sex estimation. The present study aimed to analyze the morphometric variables of the foramen magnum in Brazilian adult cranium for sex estimation. The sample was composed of 100 craniums (53 males and 47 females) from the documented collection of the Institute of Teaching and Research in Forensic Sciences. The protocol measurement was constituted of two linear measurements: maximum length of the foramen magnum and maximum breadth of the foramen magnum and two formulas to calculate the area, method one (M1) and method two (M2). Descriptive statistics showed statistically significant differences between sex (p<0.05) for all variables. The univariate discriminant functions showed an accuracy between 56.0-62.0%, and the multivariate analysis showed a percentage of accuracy between 60.0-65.0%, the greatest accuracy was found combining the two linear measurements with M1(71.7%), even after cross-validation (66%). Receiver Operating Characteristic (ROC) curve analysis showed that M2 is the best parameter for estimating sex (AUC=0.693). A reference table for Brazilians using the foramen magnum parameters was developed based on the results of the ROC curve analysis. In conclusion, the foramen magnum should be used with caution to estimate sex in forensic cases of fragmentary craniums, due to the limited accuracy.

[1]  K. Chaumoitre,et al.  Applicability and limitations of sex assessment based on foramen magnum. , 2017, Forensic science international.

[2]  R. Menezes,et al.  Morphometric evaluation of the foramen magnum for sex determination: A study from Saudi Arabia. , 2017, Journal of forensic and legal medicine.

[3]  F. Karjodkar,et al.  Sexual dimorphism of foramen magnum using Cone Beam Computed Tomography. , 2016, Journal of forensic and legal medicine.

[4]  M. Nogueira,et al.  Testing the reliability of software tools in sex and ancestry estimation in a multi-ancestral Brazilian sample. , 2014, Legal medicine.

[5]  D. Ilgüy,et al.  Measurements of the Foramen Magnum and Mandible in Relation to Sex Using CBCT , 2014, Journal of forensic sciences.

[6]  M. Viner,et al.  Sex determination from the foramen magnum , 2013 .

[7]  L. Gusmão,et al.  Revisiting the Genetic Ancestry of Brazilians Using Autosomal AIM-Indels , 2013, PloS one.

[8]  Mineo Yoshino,et al.  Discriminant functions for sex estimation of modern Japanese skulls. , 2013, Journal of Forensic and Legal Medicine.

[9]  N. Al-Rawi,et al.  Evaluation of foramen magnum in gender determination using helical CT scanning. , 2012, Dento maxillo facial radiology.

[10]  S. Tripathi,et al.  Sex Estimation from the Mastoid Process Among North Indians * , 2012, Journal of forensic sciences.

[11]  R. González,et al.  Determination of Sex from Juvenile Crania by Means of Discriminant Function Analysis *,† , 2012, Journal of forensic sciences.

[12]  T. Lang The Bone-Muscle Relationship in Men and Women , 2011, Journal of osteoporosis.

[13]  R. Rai,et al.  An Osteometric Study of Northern Indian Populations for Sexual Dimorphism in Craniofacial Region , 2011, Journal of forensic sciences.

[14]  M Katherine Spradley,et al.  Sex Estimation in Forensic Anthropology: Skull Versus Postcranial Elements , 2011, Journal of forensic sciences.

[15]  M. Hutz,et al.  The Genomic Ancestry of Individuals from Different Geographical Regions of Brazil Is More Uniform Than Expected , 2011, PloS one.

[16]  Bridget F B Algee-Hewitt,et al.  Estimation and evidence in forensic anthropology: sex and race. , 2009, American journal of physical anthropology.

[17]  Mubarak Ariyo Bidmos,et al.  The skull and humerus in the determination of sex: reliability of discriminant function equations. , 2009, Forensic science international.

[18]  I. S. Galdames,et al.  Sexual Dimorphism in the Foramen Magnum Dimensions , 2009 .

[19]  Cristina Cattaneo,et al.  Forensic anthropology: developments of a classical discipline in the new millennium. , 2007, Forensic science international.

[20]  J. Fleiss The design and analysis of clinical experiments , 1987 .

[21]  W. R. Teixeira Sex identification utilizing the size of the foramen magnum , 1982, The American journal of forensic medicine and pathology.

[22]  W. Howells,et al.  Cranial Variation in Man: A Study by Multivariate Analysis of Patterns of Difference Among Recent Human Populations , 1975 .

[23]  E. Giles,et al.  Sex determination by discriminant function analysis of crania. , 1963, American journal of physical anthropology.

[24]  Daniel Franklin,et al.  Estimation of sex from cranial measurements in a Western Australian population. , 2013, Forensic science international.

[25]  Mangala Gowri S R,et al.  Sex determination of human mandible using metrical parameters. , 2013, Journal of clinical and diagnostic research : JCDR.

[26]  René Gapert,et al.  Sex determination from the foramen magnum: discriminant function analysis in an eighteenth and nineteenth century British sample , 2008, International Journal of Legal Medicine.

[27]  D. Ubelaker,et al.  Standards for Data Collection from Human Skeletal Remains , 1994 .

[28]  G. P. Pal,et al.  Matrical Studies with sexual diamorphism in foramen magnum of human crania , 1984 .