The evolution of bioprosthetic heart valve design and its impact on durability.

Bioprosthetic heart valves have evolved over the years into remarkably useful and predictable devices. During this process, a number of specific designs have come and gone, and a few have remained. Many design changes were successful, and many were not. This article will describe the successes and failures of the various bioprosthetic valve designs and will detail the specific reasons why a particular design change succeeded or failed to improve bioprosthetic valve performance.

[1]  M A Dokainish,et al.  Numerical simulation of leaflet flexure in bioprosthetic valves mounted on rigid and expansile stents. , 1993, Journal of biomechanics.

[2]  G. Thiene,et al.  Porcine valve durability: a comparison between Hancock standard and Hancock II bioprostheses. , 1995, The Annals of thoracic surgery.

[3]  J. Gavin,et al.  Early follow-up of patients with the Medtronic Intact porcine valve. A new cardiac bioprosthesis. , 1989, The Journal of thoracic and cardiovascular surgery.

[4]  R. Barnes,et al.  Infective endocarditis: an epidemiological review of 128 episodes. , 1999, The Journal of infection.

[5]  F J Schoen,et al.  Founder's Award, 25th Annual Meeting of the Society for Biomaterials, perspectives. Providence, RI, April 28-May 2, 1999. Tissue heart valves: current challenges and future research perspectives. , 1999, Journal of biomedical materials research.

[6]  P D Stein,et al.  Relation of calcification to torn leaflets of spontaneously degenerated porcine bioprosthetic valves. , 1985, The Annals of thoracic surgery.

[7]  D. Bracco,et al.  LOW PROFILE BIOPROSTHESIS FOR CARDIAC VALVE REPLACEMENT: EARLY CLINICAL RESULTS. , 1977, Cardiovascular diseases.

[8]  Love Jw.  Autologous pericardial reconstruction of semilunar valves. , 1998 .

[9]  L. Cohn,et al.  Twenty-year follow-up of the Hancock modified orifice porcine aortic valve. , 1998, The Annals of thoracic surgery.

[10]  F J Schoen,et al.  Calcification of bovine pericardium used in cardiac valve bioprostheses. Implications for the mechanisms of bioprosthetic tissue mineralization. , 1986, The American journal of pathology.

[11]  Wright Jt.  A pulsatile flow study comparing the Hancock porcine xenograft aortic valve prostheses models 242 and 250. , 1977 .

[12]  G. Thiene,et al.  Low-profile porcine bioprosthesis (Liotta): pathologic findings and mode of failure in the long-term. , 1996, The Journal of heart valve disease.

[13]  S. Gabbay,et al.  Do heart valve bioprostheses degenerate for metabolic or mechanical reasons? , 1988, The Journal of thoracic and cardiovascular surgery.

[14]  L N Scotten,et al.  New generation tissue valves. Their in vitro function in the mitral position. , 1984, The Journal of thoracic and cardiovascular surgery.

[15]  F. J. Thomson,et al.  Influence of fixation conditions on the performance of glutaraldehyde-treated porcine aortic valves: towards a more scientific basis. , 1979, Thorax.

[16]  C. Peniston,et al.  Medtronic mosaic porcine bioprosthesis satisfactory early clinical performance. , 1998, The Annals of thoracic surgery.

[17]  J. W. Love,et al.  Experimental evaluation of an autologous tissue heart valve. , 1992, The Journal of heart valve disease.

[18]  Y. S. Lee.  Calcification of porcine bioprosthesis implanted into human heart: high resolution scanning electron microscopic and scanning tunneling microscopic investigation. , 1994, Journal of electron microscopy.

[19]  V. Walley,et al.  Patterns of failure in Ionescu-Shiley bovine pericardial bioprosthetic valves. , 1987, The Journal of thoracic and cardiovascular surgery.

[20]  M. S. Hamid,et al.  Mechanical stresses on closed cusps of porcine bioprosthetic valves: correlation with sites of calcification. , 1986, The Annals of thoracic surgery.

[21]  P. Walker,et al.  Hydrodynamic performance of the Medtronic Freestyle Aortic Root Bioprosthesis. , 1994, The Journal of heart valve disease.

[22]  W. Edwards,et al.  Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves. , 1997, The Journal of clinical investigation.

[23]  J. Fisher,et al.  Fatigue analysis of clinical bioprosthetic heart valves manufactured using photooxidized bovine pericardium. , 2000, The Journal of heart valve disease.

[24]  G. Christie.  Computer modelling of bioprosthetic heart valves. , 1992, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[25]  E Wolner,et al.  Toxic effects of aldehydes released from fixed pericardium on bovine aortic endothelial cells. , 1989, Journal of biomedical materials research.

[26]  H. Anderson,et al.  Matrix Vesicles in Atherosclerotic Calcification 1 , 1983, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[27]  B. Boyan,et al.  Stabilization of pericardial tissue by dye-mediated photooxidation. , 1994, Journal of biomedical materials research.

[28]  Longitudinal and radial distensibility of the porcine aortic root. , 1995, The Annals of thoracic surgery.

[29]  J Fisher,et al.  Frame-mounted porcine valve bioprostheses: preparation during aortic-root dilation. Biomechanics and design considerations. , 1993, The Journal of thoracic and cardiovascular surgery.

[30]  I. Vesely,et al.  Dynamic loading increases strength of tissue-engineered chordae tendineae , 2002, Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.

[31]  J. Costerton,et al.  Direct confocal microscopy studies of the bacterial colonization in vitro of a silver-coated heart valve sewing cuff. , 2000, International journal of antimicrobial agents.

[32]  F. Schoen.  Cardiac valve prostheses: review of clinical status and contemporary biomaterials issues. , 1987, Journal of biomedical materials research.

[33]  B. Chaitman,et al.  Late tears in leaflets of porcine bioprostheses in adults. , 1984, The Annals of thoracic surgery.

[34]  R. Levy,et al.  The role of glutaraldehyde-induced cross-links in calcification of bovine pericardium used in cardiac valve bioprostheses. , 1987, The American journal of pathology.

[35]  R. Hetzer,et al.  Paravalvular leak and other events in silzone-coated mechanical heart valves: a report from AVERT. , 2002, The Annals of thoracic surgery.

[36]  M. Thubrikar,et al.  Role of mechanical stress in calcification of aortic bioprosthetic valves. , 1983, The Journal of thoracic and cardiovascular surgery.

[37]  I Vesely,et al.  Biaxial strain analysis of the porcine aortic valve. , 1995, The Annals of thoracic surgery.

[38]  B. Rutt,et al.  Aortic Valve/Root Interactions in Porcine Hearts: Implications for Bioprosthetic Valve Sizing , 1991, Journal of cardiac surgery.

[39]  M. S. Hamid,et al.  Influence of stent height upon stresses on the cusps of closed bioprosthetic valves. , 1986, Journal of biomechanics.

[40]  M Jones,et al.  Structure and classification of cuspal tears and perforations in porcine bioprosthetic cardiac valves implanted in patients. , 1981, The American journal of cardiology.

[41]  M Jones,et al.  Calcific deposits in porcine bioprostheses: structure and pathogenesis. , 1980, The American journal of cardiology.

[42]  I. Vesely,et al.  Aortic root dilation prior to valve opening explained by passive hemodynamics. , 2000, The Journal of heart valve disease.

[43]  K S Kunzelman,et al.  Aortic root and valve relationships. Impact on surgical repair. , 1994, The Journal of thoracic and cardiovascular surgery.

[44]  D. Burstow,et al.  The Cryolife‐O'Brien Stentless Aortic Porcine Xenograft Valve , 1998, Journal of cardiac surgery.

[45]  I Vesely,et al.  Tissue damage and calcification may be independent mechanisms of bioprosthetic heart valve failure. , 2001, The Journal of heart valve disease.

[46]  M. Sacks,et al.  Biaxial mechanical properties of the native and glutaraldehyde-treated aortic valve cusp: Part II--A structural constitutive model. , 2000, Journal of biomechanical engineering.

[47]  R. Bianco,et al.  In vivo efficacy of silver-coated fabric against Staphylococcus epidermidis. , 2000, The Journal of heart valve disease.

[48]  M E Nimni,et al.  Toxic reactions evoked by glutaraldehyde-fixed pericardium and cardiac valve tissue bioprosthesis. , 1984, Journal of biomedical materials research.

[49]  I Vesely,et al.  Tissue buckling as a mechanism of bioprosthetic valve failure. , 1988, The Annals of thoracic surgery.

[50]  F J Schoen,et al.  Biologic determinants of dystrophic calcification and osteocalcin deposition in glutaraldehyde-preserved porcine aortic valve leaflets implanted subcutaneously in rats. , 1983, The American journal of pathology.

[51]  Ivan Vesely,et al.  Characteristics of compressive strains in porcine aortic valves cusps. , 2002, The Journal of heart valve disease.

[52]  M. M. Adamczyk,et al.  Biaxial strain properties of elastase-digested porcine aortic valves. , 2000, The Journal of heart valve disease.