Delaying the initiation of intact breast irradiation for patients with lymph node positive breast cancer increases the risk of local recurrence

Background. The impact of delaying irradiation to the intact breast for patients receiving chemotherapy for lymph node positive breast cancer is controversial.

[1]  C. Redmond,et al.  Fraud in breast-cancer trials. , 1994, The New England journal of medicine.

[2]  S. Broder Fraud in breast-cancer trials. , 1994, The New England journal of medicine.

[3]  L. Holmberg,et al.  Sector resection with or without postoperative radiotherapy for stage I breast cancer: five-year results of a randomized trial. Uppsala-Orebro Breast Cancer Study Group. , 1994, Journal of the National Cancer Institute.

[4]  A. Recht,et al.  Sequencing of irradiation and chemotherapy for early-stage breast cancer. , 1994, Oncology.

[5]  S. Swain In situ or localized breast cancer--how much treatment is needed? , 1993, The New England journal of medicine.

[6]  A. Luini,et al.  Radiotherapy after breast-preserving surgery in women with localized cancer of the breast. , 1993, The New England journal of medicine.

[7]  Terry L. Smith,et al.  The order of administration of chemotherapy and radiation and its effect on the local control of operable breast cancer , 1993, Cancer.

[8]  F. Vicini,et al.  Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early-stage, node-positive breast cancer: sequencing, timing, and outcome. , 1991, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  Anna L. Brown,et al.  Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowe , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[10]  K. Kiel,et al.  Technique for breast irradiation using custom blocks conforming to the chest wall contour. , 1990, International Journal of Radiation Oncology, Biology, Physics.

[11]  B Fisher,et al.  Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. , 1989, The New England journal of medicine.

[12]  A. Luini,et al.  Comparison of Halsted mastectomy with quadrantectomy, axillary dissection, and radiotherapy in early breast cancer: long-term results. , 1986, European journal of cancer & clinical oncology.

[13]  D. Sarrazin Conservative treatment versus mastectomy in breast cancer tumors with macroscopic diameter of 20 millimeters or less , 1985 .

[14]  C. Hill,et al.  Conservative treatment versus mastectomy in breast cancer tumors with macroscopic diameter of 20 millimeters or less the experience of the institut gustave‐roussy , 1984, Cancer.

[15]  C. Begg,et al.  Timing of radiotherapy in the treatment of early-stage breast cancer. , 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  T. Buchholz,et al.  Effect of delay in radiation in the combined modality treatment of breast cancer. , 1993, International journal of radiation oncology, biology, physics.