A tag at the carboxy terminus prevents membrane integration of VDAC1 in mammalian mitochondria.

[1]  Stephan Kutik,et al.  Evolution of mitochondrial protein biogenesis. , 2009, Biochimica et biophysica acta.

[2]  J. Tommassen,et al.  Signals in bacterial β-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria , 2009, Proceedings of the National Academy of Sciences.

[3]  R. Lightowlers,et al.  Probing the orientation of yeast VDAC1 in vivo , 2009, FEBS letters.

[4]  Michael Habeck,et al.  Structure of the human voltage-dependent anion channel , 2008, Proceedings of the National Academy of Sciences.

[5]  Sebastian Hiller,et al.  References and Notes Supporting Online Material Materials and Methods Figures S1 to S5 Table S1 References Solution Structure of the Integral Human Membrane Protein Vdac-1 in Detergent Micelles , 2022 .

[6]  Thomas Becker,et al.  Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins , 2008, Cell.

[7]  Albert Sickmann,et al.  Multiple pathways for sorting mitochondrial precursor proteins , 2008, EMBO reports.

[8]  T. Rudel,et al.  Conserved roles of Sam50 and metaxins in VDAC biogenesis , 2007, EMBO reports.

[9]  R. Benz,et al.  Determination of the Conformation of the Human VDAC1 N‐Terminal Peptide, a Protein Moiety Essential for the Functional Properties of the Pore , 2007, Chembiochem : a European journal of chemical biology.

[10]  W. Craigen,et al.  Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death , 2007, Nature Cell Biology.

[11]  J. Tommassen,et al.  Assembly Factor Omp85 Recognizes Its Outer Membrane Protein Substrates by a Species-Specific C-Terminal Motif , 2006, PLoS biology.

[12]  V. Shoshan-Barmatz,et al.  The voltage-dependent anion channel-1 modulates apoptotic cell death , 2005, Cell Death and Differentiation.

[13]  D. Stojanovski,et al.  Dissection of the Mitochondrial Import and Assembly Pathway for Human Tom40* , 2005, Journal of Biological Chemistry.

[14]  W. Neupert,et al.  Assembly of the TOB Complex of Mitochondria* , 2005, Journal of Biological Chemistry.

[15]  R. Waller,et al.  The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria , 2004, The Journal of cell biology.

[16]  Walter Neupert,et al.  Evolutionary conservation of biogenesis of β-barrel membrane proteins , 2003, Nature.

[17]  N. Pfanner,et al.  An Essential Role of Sam50 in the Protein Sorting and Assembly Machinery of the Mitochondrial Outer Membrane* , 2003, Journal of Biological Chemistry.

[18]  B. Schönfisch,et al.  Machinery for protein sorting and assembly in the mitochondrial outer membrane , 2003, Nature.

[19]  J. Grimm,et al.  VDAC and the bacterial porin PorB of Neisseria gonorrhoeae share mitochondrial import pathways , 2002, The EMBO journal.

[20]  E. Mekada,et al.  Characterization of Rat TOM40, a Central Component of the Preprotein Translocase of the Mitochondrial Outer Membrane* , 2000, The Journal of Biological Chemistry.

[21]  T. Lithgow,et al.  A Toxic Fusion Protein Accumulating between the Mitochondrial Membranes Inhibits Protein Assembly in Vivo * , 1998, The Journal of Biological Chemistry.

[22]  W. Craigen,et al.  A Novel Isoform of the Mitochondrial Outer Membrane Protein VDAC3 via Alternative Splicing of a 3-Base Exon , 1998, The Journal of Biological Chemistry.

[23]  A. Siddiqui,et al.  Isolation of a novel human voltage-dependent anion channel gene , 1998, European Journal of Human Genetics.

[24]  J. Adelman,et al.  Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel. , 1993, The Journal of biological chemistry.