Syndrome comorbidity in patients diagnosed with a DSM-III-R anxiety disorder.

One hundred thirty patients presenting at an anxiety disorders research clinic were administered a structured interview (i.e., Anxiety Disorders Interview Schedule-Revised). Diagnoses were made in accordance with Diagnostic and Statistical Manual (rev. 3rd ed.) criteria. Seventy percent of patients received at least one additional but secondary Axis I diagnosis. The most common additional diagnoses were simple and social phobia, which were assigned to nearly one third of all patients. In addition, 33% of anxiety disorder patients received an additional diagnosis of a depressive mood disorder (i.e., dysthymia or major depression). The distribution of specific additional diagnoses are presented for each principal anxiety disorder category. The scientific and clinical implications of comorbidity are discussed while considering the relatively high patterns of syndrome comorbidity found in the present study, which is consistent with several earlier studies.

[1]  L. Grunhaus Clinical and psychobiological characteristics of simultaneous panic disorder and major depression. , 1988, American Journal of Psychiatry.

[2]  R. Rubin,et al.  Secondary depression in panic disorder and agoraphobia. I. Frequency, severity, and response to treatment. , 1988, Archives of general psychiatry.

[3]  W. Coryell,et al.  Placebo response in panic disorder. , 1988, The American journal of psychiatry.

[4]  J. Mezzich,et al.  DSM-III classification of the anxiety disorders: a psychometric study. , 1986, Journal of abnormal psychology.

[5]  E. Blanchard,et al.  Co-Morbidity and Depression among the Anxiety Disorders: Issues in Diagnosis and Classification , 1986, The Journal of nervous and mental disease.

[6]  B. Garssen,et al.  Comorbidity among the anxiety disorders , 1989 .

[7]  E. Blanchard,et al.  The phenomenon of panic. , 1985, Journal of abnormal psychology.

[8]  O. Cameron,et al.  Symptom profiles of patients with DSM-III anxiety disorders. , 1986, The American journal of psychiatry.

[9]  H. Eysenck A Model for Personality , 1981 .

[10]  D. Watson,et al.  Positive and negative affectivity and their relation to anxiety and depressive disorders. , 1988, Journal of abnormal psychology.

[11]  D. Watson,et al.  Negative affectivity: the disposition to experience aversive emotional states. , 1984, Psychological bulletin.

[12]  S. Turner,et al.  Is panic a unique emotional experience? , 1989, Behaviour research and therapy.

[13]  Stein Mb,et al.  Social phobic symptoms in patients with panic disorder: practical and theoretical implications. , 1989 .

[14]  R. Michels,et al.  Diagnostic and Statistical Manual of Mental Disorders, 3rd ed , 1981 .

[15]  David H. Barlow,et al.  Anxiety and its disorders : the nature and treatment of anxiety and panic , 1988 .