Integrated Metabolomics and Proteomics Analysis of Hippocampus in a Rat Model of Depression

[1]  P. Ascher,et al.  Glycine potentiates the NMDA response in cultured mouse brain neurons , 1987, Nature.

[2]  G. Gebhart,et al.  Special Report: The 1996 Guide for the Care and Use of Laboratory Animals. , 1997, ILAR journal.

[3]  J. Bonifacino,et al.  A Novel Clathrin Adaptor Complex Mediates Basolateral Targeting in Polarized Epithelial Cells , 1999, Cell.

[4]  A. Das,et al.  Molecular Cloning and Expression of Mammalian Peroxisomaltrans-2-Enoyl-coenzyme A Reductase cDNAs* , 2000, The Journal of Biological Chemistry.

[5]  Philip Smith,et al.  Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins. , 2001, The Biochemical journal.

[6]  Paul J. Harrison,et al.  The neuropathology of primary mood disorder. , 2002, Brain : a journal of neurology.

[7]  A. Castle,et al.  Role of secretory carrier membrane protein SCAMP2 in granule exocytosis. , 2002, Molecular biology of the cell.

[8]  G. MacQueen,et al.  The role of the hippocampus in the pathophysiology of major depression. , 2004, Journal of psychiatry & neuroscience : JPN.

[9]  J. Thome,et al.  Differential regulation of synaptic vesicle proteins by antidepressant drugs , 2004, The Pharmacogenomics Journal.

[10]  D. Vance,et al.  Phospholipid biosynthesis in mammalian cells. , 2004, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[11]  Michael Marriott,et al.  Lower hippocampal volume in patients suffering from depression: a meta-analysis. , 2004, The American journal of psychiatry.

[12]  Xiaoping Zhou,et al.  Reticulon proteins: emerging players in neurodegenerative diseases , 2006, Cellular and Molecular Life Sciences CMLS.

[13]  Leon Lagnado,et al.  Clathrin-Mediated Endocytosis Is the Dominant Mechanism of Vesicle Retrieval at Hippocampal Synapses , 2006, Neuron.

[14]  Eberhard Fuchs,et al.  Stress, depression and hippocampal apoptosis. , 2006, CNS & neurological disorders drug targets.

[15]  Fa-jin Lv,et al.  Neurogenesis and major depression: implications from proteomic analyses of hippocampal proteins in a rat depression model , 2007, Neuroscience Letters.

[16]  J. Suvisaari,et al.  Impact of psychiatric disorders on health-related quality of life: general population survey , 2007, British Journal of Psychiatry.

[17]  Tianlu Chen,et al.  Metabolic profiling reveals disorder of amino acid metabolism in four brain regions from a rat model of chronic unpredictable mild stress , 2008, FEBS letters.

[18]  C. Pittenger,et al.  Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms , 2008, Neuropsychopharmacology.

[19]  G. Wegener,et al.  Differential expression of synaptic vesicle proteins after repeated electroconvulsive seizures in rat frontal cortex and hippocampus , 2008, Synapse.

[20]  K. Hiraga,et al.  Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia. , 2008, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

[21]  A. Sidhu,et al.  Partial regulation of serotonin transporter function by γ-synuclein , 2009, Neuroscience Letters.

[22]  A. Sidhu,et al.  Desipramine Modulation of α-, γ-Synuclein, and the Norepinephrine Transporter in an Animal Model of Depression , 2009, Neuropsychopharmacology.

[23]  M. Mann,et al.  Universal sample preparation method for proteome analysis , 2009, Nature Methods.

[24]  P. Gebicke-haerter,et al.  Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression , 2010, Neuropharmacology.

[25]  Xiong Cao,et al.  Behavioral animal models of depression , 2010, Neuroscience Bulletin.

[26]  J. Reddy,et al.  Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα , 2010, Laboratory Investigation.

[27]  A. L. Garcia-Garcia,et al.  Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex , 2011, European Neuropsychopharmacology.

[28]  Timothy M. D. Ebbels,et al.  Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA , 2011 .

[29]  D. Schaid,et al.  Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics‐Informed Pharmacogenomics , 2011, Clinical pharmacology and therapeutics.

[30]  F. Holsboer,et al.  Proteomic and Metabolomic Profiling of a Trait Anxiety Mouse Model Implicate Affected Pathways* , 2011, Molecular & Cellular Proteomics.

[31]  P. Novick,et al.  Role of Rab GTPases in membrane traffic and cell physiology. , 2011, Physiological reviews.

[32]  F. Holsboer,et al.  Proteomics and Metabolomics Analysis of a Trait Anxiety Mouse Model Reveals Divergent Mitochondrial Pathways , 2011, Biological Psychiatry.

[33]  S. Christiansen,et al.  Candidate Hippocampal Biomarkers of Susceptibility and Resilience to Stress in a Rat Model of Depression* , 2012, Molecular & Cellular Proteomics.

[34]  Ellen Frank,et al.  Major depressive disorder: new clinical, neurobiological, and treatment perspectives , 2012, The Lancet.

[35]  Peng Xie,et al.  Plasma metabonomics as a novel diagnostic approach for major depressive disorder. , 2012, Journal of proteome research.

[36]  S. Mishra,et al.  Neurodegenerative evidences during early onset of depression in CMS rats as detected by proton magnetic resonance spectroscopy at 7T , 2012, Behavioural Brain Research.

[37]  G. Sanacora,et al.  Towards a glutamate hypothesis of depression An emerging frontier of neuropsychopharmacology for mood disorders , 2012, Neuropharmacology.

[38]  S. Lim,et al.  Hypoxia Modulates A431 Cellular Pathways Association to Tumor Radioresistance and Enhanced Migration Revealed by Comprehensive Proteomic and Functional Studies* , 2012, Molecular & Cellular Proteomics.

[39]  P. Xie,et al.  Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation. , 2012, The international journal of neuropsychopharmacology.

[40]  P. Guest,et al.  Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function , 2012, European Archives of Psychiatry and Clinical Neuroscience.

[41]  M. Webster,et al.  Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients , 2012, Translational Psychiatry.

[42]  Peng Xie,et al.  Identification and Validation of Urinary Metabolite Biomarkers for Major Depressive Disorder* , 2012, Molecular & Cellular Proteomics.

[43]  P. Xie,et al.  A novel urinary metabolite signature for diagnosing major depressive disorder. , 2013, Journal of proteome research.

[44]  Robert C. Thompson,et al.  Glutamate transporters: a key piece in the glutamate puzzle of major depressive disorder. , 2013, Journal of psychiatric research.

[45]  E. Holmes,et al.  A Combined Metabonomic and Proteomic Approach Identifies Frontal Cortex Changes in a Chronic Phencyclidine Rat Model in Relation to Human Schizophrenia Brain Pathology , 2013, Neuropsychopharmacology.

[46]  Y. Yang,et al.  Proteomics reveals energy and glutathione metabolic dysregulation in the prefrontal cortex of a rat model of depression , 2013, Neuroscience.

[47]  P. Xie,et al.  GC-MS based metabolomics identification of possible novel biomarkers for schizophrenia in peripheral blood mononuclear cells. , 2014, Molecular bioSystems.

[48]  Ok-Ho Shin,et al.  Exocytosis and synaptic vesicle function. , 2014, Comprehensive Physiology.

[49]  A. Craig,et al.  Calsyntenin-3 Molecular Architecture and Interaction with Neurexin 1α* , 2014, The Journal of Biological Chemistry.

[50]  M. Santana,et al.  Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress , 2014, Neuroscience.

[51]  L. Fratiglioni,et al.  Interactive effects of KIBRA and CLSTN2 polymorphisms on episodic memory in old-age unipolar depression , 2014, Neuropsychologia.

[52]  E. Want,et al.  Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model. , 2015, Journal of proteome research.

[53]  P. Xie,et al.  Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depression , 2015, Behavioural Brain Research.

[54]  Peng Xie,et al.  Combined Metabolomics and Proteomics Analysis of Major Depression in an Animal Model: Perturbed Energy Metabolism in the Chronic Mild Stressed Rat Cerebellum. , 2015, Omics : a journal of integrative biology.

[55]  P. Xie,et al.  iTRAQ-based quantitative analysis of hippocampal postsynaptic density-associated proteins in a rat chronic mild stress model of depression , 2015, Neuroscience.

[56]  J. Beck,et al.  Role of calcium, glutamate and NMDA in major depression and therapeutic application , 2016, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[57]  P. Xie,et al.  The identification of metabolic disturbances in the prefrontal cortex of the chronic restraint stress rat model of depression , 2016, Behavioural Brain Research.

[58]  Jos Kleinjans,et al.  Transcriptomic and metabolomic data integration , 2016, Briefings Bioinform..

[59]  R. Cui,et al.  The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex , 2017, Neural plasticity.

[60]  Jie Luo,et al.  Sub-anesthetic doses of ketamine exert antidepressant-like effects and upregulate the expression of glutamate transporters in the hippocampus of rats , 2017, Neuroscience Letters.

[61]  T. Amstislavskaya,et al.  Features of emotional and social behavioral phenotypes of calsyntenin2 knockout mice , 2017, Behavioural Brain Research.

[62]  Y. Mori,et al.  The β4 subunit of the voltage-gated calcium channel (Cacnb4) regulates the rate of cell proliferation in Chinese Hamster Ovary cells. , 2017, The international journal of biochemistry & cell biology.

[63]  Peng Xie,et al.  Metabolomics identifies perturbations in amino acid metabolism in the prefrontal cortex of the learned helplessness rat model of depression , 2017, Neuroscience.

[64]  Menachem Motiei,et al.  Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression , 2017, Theranostics.