The ion channel activator CyPPA inhibits melanogenesis via the GSK3β/β-catenin pathway.
暂无分享,去创建一个
S. Chang | C. Leem | Y. Lee | Hong-il Cho | Seunghyun Bang | M. Jung | T. Noh | Inki Kim
[1] Z. Jin,et al. Paracrine regulation of melanogenesis , 2018, The British journal of dermatology.
[2] S. Chang,et al. Treatment of Melasma and Post-Inflammatory Hyperpigmentation by a Picosecond 755-nm Alexandrite Laser in Asian Patients , 2017, Annals of dermatology.
[3] S. Chang,et al. Dopamine D4 receptor antagonist inhibits melanogenesis through transcriptional downregulation of MITF via ERK signalling , 2016, Experimental dermatology.
[4] S. Y. Kim,et al. The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K‐/Akt‐mediated tyrosinase degradation , 2015, Experimental dermatology.
[5] N. Chen,et al. The molecular mechanism of rotenone-induced α-synuclein aggregation: emphasizing the role of the calcium/GSK3β pathway. , 2015, Toxicology letters.
[6] S. Ishikawa,et al. Accelerated Recovery of Mitochondrial Membrane Potential by GSK-3β Inactivation Affords Cardiomyocytes Protection from Oxidant-Induced Necrosis , 2014, PloS one.
[7] V. Vallon,et al. Molecular Mechanisms of Calcium-sensing Receptor-mediated Calcium Signaling in the Modulation of Epithelial Ion Transport and Bicarbonate Secretion* , 2014, The Journal of Biological Chemistry.
[8] Tzu-rong Su,et al. Inhibition of Melanogenesis by Gallic Acid: Possible Involvement of the PI3K/Akt, MEK/ERK and Wnt/β-Catenin Signaling Pathways in B16F10 Cells , 2013, International journal of molecular sciences.
[9] C. Culmsee,et al. Activation of KCNN3/SK3/KCa2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia , 2012, Glia.
[10] K. Kawakami,et al. Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish , 2012, PloS one.
[11] Blazej Zbytek,et al. Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system. , 2012, Advances in anatomy, embryology, and cell biology.
[12] T. Gudermann,et al. Natural and synthetic modulators of SK (Kca2) potassium channels inhibit magnesium‐dependent activity of the kinase‐coupled cation channel TRPM7 , 2012, British journal of pharmacology.
[13] Shigeru Kondo,et al. Pigment Pattern Formation by Contact-Dependent Depolarization , 2012, Science.
[14] A. Bosserhoff,et al. Migration-associated secretion of melanoma inhibitory activity at the cell rear is supported by KCa3.1 potassium channels , 2010, Cell Research.
[15] B. Dréno,et al. ERK‐regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma , 2010, Pigment cell & melanoma research.
[16] V. Joulin,et al. KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility. , 2009, Experimental cell research.
[17] J. Dyck,et al. Dehydroepiandrosterone Reverses Systemic Vascular Remodeling Through the Inhibition of the Akt/GSK3-β/NFAT Axis , 2009, Circulation.
[18] Yung-Hyun Choi,et al. Dichloromethane fraction of Cimicifuga heracleifolia decreases the level of melanin synthesis by activating the ERK or AKT signaling pathway in B16F10 cells , 2009, Experimental dermatology.
[19] S. D. De Smedt,et al. Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[20] Michael Boutros,et al. The art and design of genetic screens: RNA interference , 2008, Nature Reviews Genetics.
[21] D. Strøbæk,et al. Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+‐activated K+ channels , 2007, British journal of pharmacology.
[22] J. Simon,et al. Quantification of Ca(2+) binding to melanin supports the hypothesis that melanosomes serve a functional role in regulating calcium homeostasis. , 2007, Pigment cell research.
[23] Stephen L. Johnson,et al. Pigment Pattern in jaguar/obelix Zebrafish Is Caused by a Kir7.1 Mutation: Implications for the Regulation of Melanosome Movement , 2006, PLoS genetics.
[24] E. Steingrímsson,et al. The Microphthalmia-Associated Transcription Factor Mitf Interacts with β-Catenin To Determine Target Gene Expression , 2006, Molecular and Cellular Biology.
[25] S. Heinemann,et al. Ca2+‐activated K+ channels in human melanoma cells are up‐regulated by hypoxia involving hypoxia‐inducible factor‐1α and the von Hippel‐Lindau protein , 2006 .
[26] H. Uyama,et al. Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future , 2005, Cellular and Molecular Life Sciences CMLS.
[27] D. Tobin,et al. Melanin pigmentation in mammalian skin and its hormonal regulation. , 2004, Physiological reviews.
[28] T. Böhm,et al. Properties of a potassium-selective ion channel in human melanoma cells , 1990, Pflügers Archiv.
[29] D. Bennett,et al. The color loci of mice--a genetic century. , 2003, Pigment cell research.
[30] J. Scuvée-Moreau,et al. Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry. , 2003, Current medicinal chemistry.
[31] M. Khaled,et al. Glycogen Synthase Kinase 3β Is Activated by cAMP and Plays an Active Role in the Regulation of Melanogenesis* , 2002, The Journal of Biological Chemistry.
[32] T. Kute,et al. Regulation of tyrosinase-related protein-2 (TYRP2) in human melanocytes: relationship to growth and morphology. , 2001, Pigment cell research.
[33] H. Kondoh,et al. Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma. , 1998, Pigment cell research.
[34] R. Buscà,et al. Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation* , 1996, The Journal of Biological Chemistry.
[35] N. Marrion,et al. Small-Conductance, Calcium-Activated Potassium Channels from Mammalian Brain , 1996, Science.
[36] S. Kuge,et al. The expression of tyrosinase, tyrosinase-related proteins 1 and 2 (TRP1 and TRP2), the silver protein, and a melanogenic inhibitor in human melanoma cells of differing melanogenic activities. , 1995, Pigment cell research.
[37] K. Urabe,et al. A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1). , 1994, The Journal of biological chemistry.