Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK
暂无分享,去创建一个
R. Norton | J. Tytgat | J. Macrander | M. Daly | Heidi H. Yu | S. Peigneur | M. Pennington | R. Morales | B. Krishnarjuna | C. MacRaild | S. Raghothama | Satendra S Chauhan | V. Dhawan | P. Sunanda
[1] K. Chandy,et al. Venom-derived peptide inhibitors of voltage-gated potassium channels , 2017, Neuropharmacology.
[2] E. Muñoz-Elías,et al. Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial , 2017, PloS one.
[3] K. Chandy,et al. Peptide blockers of Kv1.3 channels in T cells as therapeutics for autoimmune disease. , 2017, Current opinion in chemical biology.
[4] R. Norton,et al. The Single Disulfide-Directed β-Hairpin Fold. Dynamics, Stability, and Engineering. , 2017, Biochemistry.
[5] E. Deplazes. Molecular Simulations of Disulfide-Rich Venom Peptides with Ion Channels and Membranes , 2017, Molecules.
[6] Michael Broe,et al. Tissue-Specific Venom Composition and Differential Gene Expression in Sea Anemones , 2016, Genome biology and evolution.
[7] E. Meirovitch,et al. Structural Dynamics of the Potassium Channel Blocker ShK: SRLS Analysis of (15)N Relaxation. , 2015, The journal of physical chemistry. B.
[8] H. Scheib,et al. Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemone. , 2015, Molecular biology and evolution.
[9] Tim J. Stevens,et al. Structure calculation, refinement and validation using CcpNmr Analysis , 2015, Acta crystallographica. Section D, Biological crystallography.
[10] A. Palmer,et al. Conformational Flexibility in the Binding Surface of the Potassium Channel Blocker ShK , 2014, Chembiochem : a European journal of chemical biology.
[11] A. Cuttitta,et al. Evidence of Accelerated Evolution and Ectodermal-Specific Expression of Presumptive BDS Toxin cDNAs from Anemonia viridis , 2013, Marine drugs.
[12] F. Bezanilla,et al. Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography. , 2013, Journal of the American Chemical Society.
[13] S. Kuyucak,et al. Computational Studies of Marine Toxins Targeting Ion Channels , 2013, Marine drugs.
[14] Brian J. Smith,et al. Intracellular Trafficking of the KV1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease* , 2013, The Journal of Biological Chemistry.
[15] S. Johansen,et al. Digital Marine Bioprospecting: Mining New Neurotoxin Drug Candidates from the Transcriptomes of Cold-Water Sea Anemones , 2012, Marine drugs.
[16] G. King,et al. Development of a rational nomenclature for naming peptide and protein toxins from sea anemones. , 2012, Toxicon : official journal of the International Society on Toxinology.
[17] A. Antunes,et al. Sea Anemone (Cnidaria, Anthozoa, Actiniaria) Toxins: An Overview , 2012, Marine drugs.
[18] R. C. Rodríguez de la Vega,et al. Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes. , 2012, Biochemistry.
[19] G. Watson,et al. Force-dependent discharge of nematocysts in the sea anemone Haliplanella luciae (Verrill) , 2012, Biology Open.
[20] Shane S. Sturrock,et al. Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data , 2012, Bioinform..
[21] Serdar Kuyucak,et al. Affinity and selectivity of ShK toxin for the Kv1 potassium channels from free energy simulations. , 2012, The journal of physical chemistry. B.
[22] K. Chandy,et al. Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases. , 2012, Toxicon : official journal of the International Society on Toxinology.
[23] Shunyi Zhu,et al. Two dyad-free Shaker-type K⁺ channel blockers from scorpion venom. , 2012, Toxicon : official journal of the International Society on Toxinology.
[24] Shin-Ho Chung,et al. Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3). , 2011, Biophysical journal.
[25] R. Norton,et al. Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases. , 2011, Inflammation & allergy drug targets.
[26] J. Tytgat,et al. A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties. , 2011, Biochemical pharmacology.
[27] P. Calabresi,et al. Potassium Channel Modulation by a Toxin Domain in Matrix Metalloprotease 23* , 2009, The Journal of Biological Chemistry.
[28] Brian J. Smith,et al. Engineering a Stable and Selective Peptide Blocker of the Kv1.3 Channel in T Lymphocytes , 2009, Molecular Pharmacology.
[29] I. Khaytin,et al. Chemical synthesis and characterization of ShK toxin: a potent potassium channel inhibitor from a sea anemone. , 2009, International journal of peptide and protein research.
[30] Miron Livny,et al. BioMagResBank , 2007, Nucleic Acids Res..
[31] Jack Snoeyink,et al. Nucleic Acids Research Advance Access published April 22, 2007 MolProbity: all-atom contacts and structure validation for proteins and nucleic acids , 2007 .
[32] M. Ishida,et al. Isolation and cDNA cloning of a potassium channel peptide toxin from the sea anemone Anemonia erythraea. , 2006, Toxicon : official journal of the International Society on Toxinology.
[33] Yehu Moran,et al. When positive selection of neurotoxin genes is missing , 2006, The FEBS journal.
[34] M. O’Bryan,et al. The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling* , 2006, Journal of Biological Chemistry.
[35] Tomohiro Honma,et al. Peptide Toxins in Sea Anemones: Structural and Functional Aspects , 2006, Marine Biotechnology.
[36] Wayne Boucher,et al. The CCPN data model for NMR spectroscopy: Development of a software pipeline , 2005, Proteins.
[37] M. De Waard,et al. Contribution of the functional dyad of animal toxins acting on voltage‐gated Kv1‐type channels , 2005, Journal of peptide science : an official publication of the European Peptide Society.
[38] A. Ménez,et al. Comparison of sea anemone and scorpion toxins binding to Kv1 channels: an example of convergent evolution. , 2004, Toxicon : official journal of the International Society on Toxinology.
[39] M. Ayeb,et al. Kbot1, a three disulfide bridges toxin from Buthus occitanus tunetanus venom highly active on both SK and Kv channels , 2004, Peptides.
[40] Haruki Nakamura,et al. Announcing the worldwide Protein Data Bank , 2003, Nature Structural Biology.
[41] O. Gascuel,et al. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. , 2003, Systematic biology.
[42] R. C. Rodríguez de la Vega,et al. Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities. , 2002, Biochimica et biophysica acta.
[43] R. Nussinov,et al. Relationship between ion pair geometries and electrostatic strengths in proteins. , 2002, Biophysical journal.
[44] Shoba Ranganathan,et al. kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. , 2002, The Journal of biological chemistry.
[45] K. Katoh,et al. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. , 2002, Nucleic acids research.
[46] Ruth Nussinov,et al. Close‐Range Electrostatic Interactions in Proteins , 2002, Chembiochem : a European journal of chemical biology.
[47] R. Norton,et al. Designed peptide analogues of the potassium channel blocker ShK toxin. , 2001, Biochemistry.
[48] John P. Huelsenbeck,et al. MRBAYES: Bayesian inference of phylogenetic trees , 2001, Bioinform..
[49] K. Rajarathnam,et al. 13C NMR chemical shifts can predict disulfide bond formation , 2000, Journal of biomolecular NMR.
[50] E. Christian,et al. ShK-Dap22, a Potent Kv1.3-specific Immunosuppressive Polypeptide* , 1998, The Journal of Biological Chemistry.
[51] O. Pongs,et al. A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom. , 1997, The Biochemical journal.
[52] K. Jeyaseelan,et al. A new potassium channel toxin from the sea anemone Heteractis magnifica: isolation, cDNA cloning, and functional expression. , 1997, Biochemistry.
[53] N. J. Baxter,et al. Temperature dependence of 1H chemical shifts in proteins , 1997, Journal of biomolecular NMR.
[54] C. Roumestand,et al. On the Convergent Evolution of Animal Toxins , 1997, The Journal of Biological Chemistry.
[55] R. Norton,et al. Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone , 1996, Nature Structural Biology.
[56] I. Khaytin,et al. Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain. , 1996, Biochemical and biophysical research communications.
[57] A. J. Shaka,et al. Water Suppression That Works. Excitation Sculpting Using Arbitrary Wave-Forms and Pulsed-Field Gradients , 1995 .
[58] V. Saudek,et al. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions , 1992, Journal of biomolecular NMR.
[59] P. Wright,et al. Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy , 1991 .
[60] C. Roumestand,et al. Three-dimensional structure of natural charybdotoxin in aqueous solution by 1H-NMR. Charybdotoxin possesses a structural motif found in other scorpion toxins. , 1991, European journal of biochemistry.
[61] A. Redfield,et al. Molecular structure of charybdotoxin, a pore-directed inhibitor of potassium ion channels. , 1990, Science.
[62] A. J. Shaka,et al. Iterative schemes for bilinear operators; application to spin decoupling , 1988 .
[63] Timothy F. Havel,et al. Protein structures in solution by nuclear magnetic resonance and distance geometry. The polypeptide fold of the basic pancreatic trypsin inhibitor determined using two different algorithms, DISGEO and DISMAN. , 1987, Journal of molecular biology.
[64] K. Chandy,et al. Voltage-gated potassium channels are required for human T lymphocyte activation , 1984, The Journal of experimental medicine.
[65] J. Thornton,et al. Ion-pairs in proteins. , 1983, Journal of molecular biology.
[66] Marilyn A. Anderson,et al. Plant defensins: Common fold, multiple functions , 2013 .
[67] R. Norton. Sea Anemone Venom Peptides , 2006 .
[68] P. Güntert. Automated NMR structure calculation with CYANA. , 2004, Methods in molecular biology.
[69] H. Bosshard,et al. Protein stabilization by salt bridges: concepts, experimental approaches and clarification of some misunderstandings , 2004, Journal of molecular recognition : JMR.
[70] Charles D Schwieters,et al. The Xplor-NIH NMR molecular structure determination package. , 2003, Journal of magnetic resonance.
[71] M. Chial,et al. in simple , 2003 .
[72] R. Norton,et al. Ionisation behaviour and solution properties of the potassium-channel blocker ShK toxin. , 1998, European journal of biochemistry.