Emerging therapeutic role of Prunella vulgaris in thyroid disease

[1]  M. Miao,et al.  Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids. , 2021, Journal of ethnopharmacology.

[2]  Xing Liao,et al.  [Systematic review and trail sequential analysis of preparation of Xiakucao for Hashimoto's thyroiditis]. , 2020, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[3]  Jing Guo,et al.  Uncovering the pharmacological mechanism of the effects of the Banxia-Xiakucao Chinese Herb Pair on sleep disorder by a systems pharmacology approach , 2020, Scientific Reports.

[4]  F. Wang,et al.  Effect of Prunella vulgaris polysaccharides on cultured orbit fibroblasts in vitro from patients with thyroid-associated ophthalmopathy. , 2020, Experimental Eye Research.

[5]  Yuanzhang Hu,et al.  Network pharmacology based virtual screening of active constituents of Prunella vulgaris L. and the molecular mechanism against breast cancer , 2020, Scientific Reports.

[6]  Y. Lei,et al.  Uncovering Active Ingredients and Mechanisms of Spica Prunellae in the Treatment of Colon Adenocarcinoma: A Study Based on Network Pharmacology and Bioinformatics. , 2020, Combinatorial chemistry & high throughput screening.

[7]  L. Liao,et al.  Mechanisms of Spica Prunellae against thyroid-associated Ophthalmopathy based on network pharmacology and molecular docking , 2020, BMC Complementary Medicine and Therapies.

[8]  Chao Yang,et al.  Characterization and anti-uterine tumor effect of extract from Prunella vulgaris L. , 2020, BMC Complementary Medicine and Therapies.

[9]  Yongsheng Zhang,et al.  Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[10]  N. Tabassum,et al.  Invivo hepatoprotective potential of extracts obtained from floral spikes of Prunella vulgaris L , 2020, Journal of Ayurveda and integrative medicine.

[11]  Jun Kim,et al.  Protective effect of Prunella vulgaris var. L extract against blue light induced damages in ARPE-19 cells and mouse retina. , 2019, Free radical biology & medicine.

[12]  Seo Yun Jung,et al.  A botanical drug composed of three herbal materials attenuates the sensorimotor gating deficit and cognitive impairment induced by MK‐801 in mice , 2019, The Journal of pharmacy and pharmacology.

[13]  Gaoxue Wang,et al.  Ursolic acid from Prunella vulgaris L. efficiently inhibits IHNV infection in vito and in vivo. , 2019, Virus research.

[14]  S. Roman,et al.  Geographic influences in the global rise of thyroid cancer , 2019, Nature Reviews Endocrinology.

[15]  Wei Gao,et al.  Root extract of Prunella vulgaris inhibits in vitro and in vivo carcinogenesis in MCF-5 human breast carcinoma via suppression of angiogenesis, induction of apoptosis, cell cycle arrest and modulation of PI3K/AKT signalling pathway. , 2019, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

[16]  Xiaosun Liu,et al.  Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis. , 2019, Annals of translational medicine.

[17]  J. Zhao,et al.  Effects of Shuganjianpihuatanxingqi decoction on mild subclinical hypothyroidism , 2018, Medicine.

[18]  H. Chou,et al.  Proteomic analysis of evodiamine‐induced cytotoxicity in thyroid cancer cells , 2018, Journal of pharmaceutical and biomedical analysis.

[19]  Jie Tang,et al.  [Extraction of flavonoids in Prunella vulgaris based on deep eutectic solvent method：application of new green solvent]. , 2018, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[20]  Xiao Luo,et al.  Oral Administration of Prunella vulgaris L Improves the Effect of Taxane on Preventing the Progression of Breast Cancer and Reduces Its Side Effects , 2018, Front. Pharmacol..

[21]  Jiman Kim,et al.  A methimazole resistant patient with Graves' disease (GD): A case report of mid-term management with herbal decoctions mainly composed of Anemarrhena Bunge. , 2018, Complementary therapies in medicine.

[22]  H. Chou,et al.  Proteomic analysis of honokiol‐induced cytotoxicity in thyroid cancer cells , 2018, Life sciences.

[23]  Tae-Hoo Yi,et al.  Prunella vulgaris L. Exerts a Protective Effect Against Extrinsic Aging Through NF-κB, MAPKs, AP-1, and TGF-β/Smad Signaling Pathways in UVB-Aged Normal Human Dermal Fibroblasts , 2018, Rejuvenation research.

[24]  L. Tonghua,et al.  Protective effects of Jiayan Kangtai granules on autoimmune thyroiditis in a rat model by modulating Th17/Treg cell balance , 2018, Journal of Traditional Chinese Medicine.

[25]  D. Ustek,et al.  Association of Pro-apoptotic Bad Gene Expression Changes with Benign Thyroid Nodules. , 2018, In vivo.

[26]  Yaqin Tu,et al.  Association of TNF-α promoter polymorphism and Graves’ disease: an updated systematic review and meta-analysis , 2018, Bioscience reports.

[27]  Yue Zhang,et al.  Shikonin Inhibites Migration and Invasion of Thyroid Cancer Cells by Downregulating DNMT1 , 2018, Medical science monitor : international medical journal of experimental and clinical research.

[28]  Hyun Seok Yoon,et al.  Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia. , 2017, Molecular Medicine Reports.

[29]  Ming Yang,et al.  Treatment of Goiter with Traditional Chinese Medicine Regimen Xing Qi Hua Ying Tang: A Clinical Study on 72 Patients with Multinodular and Diffuse Goiter. , 2018, Journal of Alternative and Complementary Medicine.

[30]  R. Khan,et al.  Effect of Launaea procumbens on thyroid glands lipid peroxidation and hormonal dysfunction: a randomized control trial , 2017, Lipids in Health and Disease.

[31]  D. Yin,et al.  The Chinese herb Prunella vulgaris promotes apoptosis in human well-differentiated thyroid carcinoma cells via the B-cell lymphoma-2/Bcl-2-associated X protein/caspase-3 signaling pathway , 2017, Oncology letters.

[32]  S. A. Sehgal,et al.  Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis. , 2017, Journal of molecular graphics & modelling.

[33]  Eun Sik Choi,et al.  Prunella vulgaris Attenuates Diabetic Renal Injury by Suppressing Glomerular Fibrosis and Inflammation. , 2017, The American journal of Chinese medicine.

[34]  Jianbo Li,et al.  Potential Antitumor Effect of Harmine in the Treatment of Thyroid Cancer , 2017, Evidence-based complementary and alternative medicine : eCAM.

[35]  Xinyu Yang,et al.  Clinical efficacy of Yingliu mixture combined with metimazole for treating diffuse goitre with hyperthyroidism and its impact on related cytokines , 2016, Pharmaceutical biology.

[36]  Yang Zhang,et al.  Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism , 2016, Molecules.

[37]  M. Schubert-Zsilavecz,et al.  Prunella vulgaris L. active components and their hypoglycemic and antinociceptive effects in alloxan-induced diabetic mice. , 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[38]  M. Farhangi,et al.  The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis: a randomized controlled trial , 2016, BMC Complementary and Alternative Medicine.

[39]  Yu–Miao Siao,et al.  Modulation of the Tumor Metastatic Microenvironment and Multiple Signal Pathways by Prunella vulgaris in Human Hepatocellular Carcinoma. , 2016, The American journal of Chinese medicine.

[40]  D. Pisetsky,et al.  The expression of microvesicles in the blood of patients with Graves' disease and its relationship to treatment , 2016, Clinical endocrinology.

[41]  Qi Huang,et al.  Modulation of T-Bet and GATA-3 expression in experimental autoimmune thyroiditis rats through ginsenoside treatment , 2016, Endocrine research.

[42]  N. Liao,et al.  [Treatment of Graves Hyperthyroidism by Jiakangling Capsule Combined with Reduction of 131I: an Efficacy Observation]. , 2016, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[43]  Jun Wang,et al.  [Huikangling Tablet Intervened Peripheral Blood Micrometastasis of Differentiated Thyroid Carcinoma]. , 2015, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[44]  Wen-Ying Yu,et al.  Antihepatofibrotic Effects of Aqueous Extract of Prunella vulgaris on Carbon Tetrachloride-Induced Hepatic Fibrosis in Rats , 2015, Planta Medica.

[45]  Min Li,et al.  [Effect of Jiakangning Capsule on Thyroid Function and Akt/mTOR Signal Pathway of Graves' Disease Mice: an Experimental Study]. , 2015, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[46]  Hong Tang,et al.  Clinical efficacy of Yingliu treatment for Graves disease. , 2015, International journal of clinical and experimental medicine.

[47]  O. Bang,et al.  An evaluation of the anti-angiogenic effect of the Korean medicinal formula “Sa-mi-yeon-geon-tang” in vitro and in ovo , 2015, BMC Complementary and Alternative Medicine.

[48]  Alessandro Antonelli,et al.  Autoimmune thyroid disorders. , 2015, Autoimmunity reviews.

[49]  F. Quan,et al.  Inhibition of estrogen signaling through depletion of estrogen receptor alpha by ursolic acid and betulinic acid from Prunella vulgaris var. lilacina. , 2014, Biochemical and biophysical research communications.

[50]  J. Todorovic,et al.  Is lymphocytic thyroiditis a unique type or merely a type of Hashimoto's thyroiditis? , 2014, Minerva Medica.

[51]  E. Babaei,et al.  Detection of survivin 2α gene expression in thyroid nodules. , 2014, Journal of cancer research and therapeutics.

[52]  L. I. Turchaninova.  [Experience of using phytopreparation Alba (root extract of the Potentilla alba) in complex treatment of thyroid pathology in children and adolescents]. , 2014, Likars'ka sprava.

[53]  V. Kravchenko,et al.  [SELENIUM EFFICIENCY IN PROPHYLAXIS AND COMPLEX TREATMENT OF DIFFUSE GOITER]. , 2014, Likars'ka sprava.

[54]  Xiao-jie Gu,et al.  Chemical constituents of Prunella vulgaris. , 2013, Journal of environmental sciences.

[55]  P. Hou,et al.  Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways. , 2013, The Journal of clinical endocrinology and metabolism.

[56]  Rudolf Eiling,et al.  Besserung der Symptome einer leichten Schilddrüsenüberfunktion mit einem Trockenextrakt aus Wolfstrappkraut (Thyreogutt® mono) , 2013, Wiener Medizinische Wochenschrift.

[57]  Liu Chun-hong,et al.  [Treatment of thirty primary hypothyroidism patients by fuzheng fujia mixture ]. , 2012, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[58]  A. Bockisch,et al.  Euthyroid goiter with and without nodules--diagnosis and treatment. , 2012, Deutsches Arzteblatt international.

[59]  Y. Lee,et al.  Prunella vulgaris Suppresses HG-Induced Vascular Inflammation via Nrf2/HO-1/eNOS Activation , 2012, International journal of molecular sciences.

[60]  A. V. Kaminskii,et al.  [Application of herbal medicine alba in treatment of patients with the pathology of thyroid]. , 2012, Likars'ka sprava.

[61]  A. N. Kvacheniuk,et al.  [The use of phytotherapy for treatment of thyroid diseases]. , 2012, Likars'ka sprava.

[62]  C. Świętaszczyk,et al.  Two hundred years after discovery of iodine--less known functions of the element in human organism. , 2012, Przeglad lekarski.

[63]  Juan Wu,et al.  [Effects of Radix Astragali on IL-1beta, TNF-alpha and antigen expression of peripheral blood mononuclear cells in patients with Graves disease]. , 2011, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[64]  R. Cabrini,et al.  Biochemical changes during goiter induction by methylmercaptoimidazol and inhibition by delta-iodolactone in rat. , 2010, Thyroid : official journal of the American Thyroid Association.

[65]  Yan Chen,et al.  Identification of Two Polysaccharides from Prunella vulgaris L. and Evaluation on Their Anti-Lung Adenocarcinoma Activity , 2010, Molecules.

[66]  P. Dixon,et al.  Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages. , 2009, Journal of agricultural and food chemistry.

[67]  Juan Guo,et al.  [Experiment research of Jiajian Yunvjian granules on hyperthyroidism graves]. , 2009, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[68]  Jie Zhang,et al.  Effects of Kang-Jia-Wan, a Chinese medicinal herb officinal, on apoptosis induction in goiter of rats. , 2009, Journal of ethnopharmacology.

[69]  Byung-Cheol Lee,et al.  An Alternative Therapy for Graves' Disease , 2008 .

[70]  Cheorl-Ho Kim,et al.  Herbal medicine Gamgungtang down-regulates autoimmunity through induction of TH2 cytokine production by lymphocytes in experimental thyroiditis model. , 2007, Journal of ethnopharmacology.

[71]  J. Bright.  Curcumin and autoimmune disease. , 2007, Advances in experimental medicine and biology.

[72]  Kun-quan Guo,et al.  [Clinical effect of Prunellae Oral Liquid on goiter with different thyroid function]. , 2007, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

[73]  Á. Hernanz,et al.  Serum concentrations of tumour necrosis factor‐alpha (TNF‐α) and soluble TNF‐α receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function , 2002 .

[74]  Á. Hernanz,et al.  Serum concentrations of tumour necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function. , 2002, Clinical endocrinology.

[75]  G. Chrousos,et al.  Apoptosis induced by FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases , 2001, Trends in Endocrinology & Metabolism.

[76]  A. Tsatsoulis,et al.  The role of Fas-mediated apoptosis in thyroid disease. , 2001, European journal of endocrinology.

[77]  C. Han,et al.  Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. , 2001, The American journal of Chinese medicine.

[78]  Y. Zhao,et al.  [Triterpenoid compounds of Prunella genus and their features of 13C NMR spectroscopy]. , 2000, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[79]  D. Cooper.  Antithyroid drugs. , 1984, The New England journal of medicine.

[80]  H. Studer,et al.  Simple goiter and its variants: euthyroid and hyperthyroid multinodular goiters. , 1982, Endocrine reviews.