Treatment of primary and metastatic bone tumors by cryosurgery.
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The first patient treated by cryosurgery (Fig 1) on Feb 10, 1964, was a 48-year-old man whose lung cancer had spread to the humerus. The painful metastasis was unrelieved by two courses of x-ray therapy, and, therefore, we decided to attempt to freeze the lesion. 1 The relief of pain in the arm was
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[3] D. Pegg. REVIEW ARTICLE: Cryobiology , 1966 .