Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS‐LDA
暂无分享,去创建一个
Yi-Zeng Liang | Foo-Tim Chau | Yizeng Liang | Lunzhao Yi | F. Chau | Jun He | Lun-Zhao Yi | D. Yuan | Jun He | Da-Lin Yuan | Da-lin Yuan
[1] Masataka Harada,et al. Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40 , 2003, Nature.
[2] Guowang Xu,et al. Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[3] P. Strålfors,et al. PPAR-γ response element activity in intact primary human adipocytes: effects of fatty acids , 2006 .
[4] C. Kahn,et al. Insulin signalling and the regulation of glucose and lipid metabolism , 2001, Nature.
[5] D. Behan,et al. The use of constitutively active GPCRs in drug discovery and functional genomics , 2002, Nature Reviews Drug Discovery.
[6] U. Das,et al. Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: effect of omega-6 fatty acids. , 2003, Nutrition.
[7] Jianren Gu,et al. Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis. , 2005, Analytical chemistry.
[8] G. Boden. Free fatty acids, insulin resistance, and type 2 diabetes mellitus. , 1999, Proceedings of the Association of American Physicians.
[9] Julian L Griffin,et al. Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis. , 2003, Current opinion in chemical biology.
[10] Travis Dunckley,et al. Discovery and development of biomarkers of neurological disease. , 2005, Drug discovery today.
[11] J. Girard. [Contribution of free fatty acids to impairment of insulin secretion and action: mechanism of beta-cell lipotoxicity]. , 2005, Medecine sciences : M/S.
[12] K. Wyne. Free fatty acids and type 2 diabetes mellitus. , 2003, The American journal of medicine.
[13] F. Hsu,et al. Characterization of phosphatidylethanolamine as a lithiated adduct by triple quadrupole tandem mass spectrometry with electrospray ionization. , 2000, Journal of mass spectrometry : JMS.
[14] F Baganz,et al. Systematic functional analysis of the yeast genome. , 1998, Trends in biotechnology.
[15] J. Rood,et al. Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults. , 2002, Diabetes care.
[16] G. Reaven,et al. Role of abnormal free fatty acid metabolism in the development of non-insulin-dependent diabetes mellitus. , 1988, The American journal of medicine.
[17] F. Karpe,et al. The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes , 2004, Diabetologia.
[18] Qing-Song Xu,et al. Generalized PLS regression , 2001 .
[19] B. Barshop. Metabolomic approaches to mitochondrial disease: correlation of urine organic acids. , 2004, Mitochondrion.
[20] Ross D. King,et al. Application of metabolomics to plant genotype discrimination using statistics and machine learning , 2002, ECCB.
[21] R. Bro,et al. Centering and scaling in component analysis , 2003 .
[22] Margaretha Adolfsson-Erici,et al. Using NMR metabolomics to identify responses of an environmental estrogen in blood plasma of fish. , 2006, Aquatic toxicology.
[23] J. McGill,et al. Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus. , 2002, Metabolism: clinical and experimental.
[24] J. Griffin,et al. Choline containing metabolites during cell transfection: an insight into magnetic resonance spectroscopy detectable changes , 2001, FEBS letters.
[25] Chan Soo Shin,et al. The effects of rosiglitazone and metformin on the plasma concentrations of resistin in patients with type 2 diabetes mellitus. , 2005, Metabolism: clinical and experimental.
[26] J. Lindon,et al. Metabonomics: a platform for studying drug toxicity and gene function , 2002, Nature Reviews Drug Discovery.
[27] G. Boden,et al. Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes. , 1995, The Journal of clinical investigation.
[28] Philip K. Hopke,et al. Discarding or downweighting high-noise variables in factor analytic models , 2003 .
[29] U. Das,et al. Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus , 2003 .
[30] V. Lobjois. « Cycler » sans cycline D , 2005 .
[31] E. Ferrannini. Rosiglitazone and lipid metabolism , 2004, Diabetologia.
[32] Michael Stumvoll,et al. Type 2 diabetes: principles of pathogenesis and therapy , 2005, The Lancet.
[33] Ming Chen,et al. A medical bioinformatics approach for metabolic disorders: Biomedical data prediction, modeling, and systematic analysis , 2006, J. Biomed. Informatics.
[34] H. Lebovitz,et al. Treatment of insulin resistance in diabetes mellitus. , 2004, European journal of pharmacology.
[35] M. Matsuda,et al. Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II diabetic patients , 2001, Diabetologia.
[36] D. Eizirik,et al. Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. , 2001, Diabetes.
[37] P. Styles,et al. Study of cytokine induced neuropathology by high resolution proton NMR spectroscopy of rat urine , 2004, FEBS letters.
[38] Jian Wang,et al. Free Fatty Acids Inhibit Insulin Signaling–Stimulated Endothelial Nitric Oxide Synthase Activation Through Upregulating PTEN or Inhibiting Akt Kinase , 2006, Diabetes.
[39] O. Fiehn. Metabolomics – the link between genotypes and phenotypes , 2004, Plant Molecular Biology.
[40] P. Strålfors,et al. PPAR-gamma response element activity in intact primary human adipocytes: effects of fatty acids. , 2006, Nutrition.
[41] L. Mueller,et al. Metabolomic analysis using optimized NMR and statistical methods. , 2006, Analytical biochemistry.
[42] H. Sauter,et al. Metabolic profiling of plants: a new diagnostic technique , 1991 .
[43] U. Das,et al. Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus. Effect of omega-3 fatty acids. , 2003, Nutrition.
[44] R. Bergman,et al. Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus , 2000, Trends in Endocrinology & Metabolism.