Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes
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R. Dwek | E. Harris | N. Zitzmann | D. Alonzi | B. Tyrrell | Andrew C Sayce | J. L. Miller | P. Beatty | M. Hill | J. L. Kiappes | A. Kato | S. Killingbeck | A. Caputo | R. Iwaki | Kyoko Kinami | D. Ide | Beatrice E. Tyrrell | Ren Iwaki | David W C Beasley | David W. C. Beasley
[1] Huey-Nan Wu,et al. Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication , 2015, Journal of Virology.
[2] J. Miller,et al. Strain-specific antiviral activity of iminosugars against human influenza A viruses , 2014, The Journal of antimicrobial chemotherapy.
[3] J. Hiscott,et al. Cellular Oxidative Stress Response Controls the Antiviral and Apoptotic Programs in Dengue Virus-Infected Dendritic Cells , 2014, PLoS pathogens.
[4] E. Harris,et al. Monocyte Recruitment to the Dermis and Differentiation to Dendritic Cells Increases the Targets for Dengue Virus Replication , 2014, PLoS pathogens.
[5] J. Connolly,et al. Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial. , 2014, The Lancet. Infectious diseases.
[6] E. Harris,et al. Innate immunity to dengue virus infection and subversion of antiviral responses. , 2014, Journal of molecular biology.
[7] Ralf Bartenschlager,et al. Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside—Caught in the Web , 2014, Journal of Virology.
[8] Jinhong Chang,et al. Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions , 2013, Antiviral Research.
[9] F. Peterson,et al. Structure of the Lectin Mannose 6-Phosphate Receptor Homology (MRH) Domain of Glucosidase II, an Enzyme That Regulates Glycoprotein Folding Quality Control in the Endoplasmic Reticulum* , 2013, The Journal of Biological Chemistry.
[10] R. Dwek,et al. An iminosugar with potent inhibition of dengue virus infection in vivo. , 2013, Antiviral research.
[11] R. Dwek,et al. Liposome-Mediated Delivery of Iminosugars Enhances Efficacy against Dengue Virus In Vivo , 2012, Antimicrobial Agents and Chemotherapy.
[12] J. Connolly,et al. Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial. , 2012, Antiviral research.
[13] Rosemarie E. Venier,et al. Miglustat as a therapeutic agent: prospects and caveats , 2012, Journal of Medical Genetics.
[14] T. Butters,et al. Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone: the effect of N-alkylation on hexosaminidase inhibition. , 2012, Chemistry.
[15] Jinhong Chang,et al. Design, synthesis, and biological evaluation of N-alkylated deoxynojirimycin (DNJ) derivatives for the treatment of dengue virus infection. , 2012, Journal of medicinal chemistry.
[16] J. Connolly,et al. Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model. , 2011, Antiviral research.
[17] Sook-San Wong,et al. Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes. , 2011, Virology.
[18] Chie Aoki,et al. Dengue virus type 2 recognizes the carbohydrate moiety of neutral glycosphingolipids in mammalian and mosquito cells , 2011, Microbiology and immunology.
[19] P. Shi,et al. Combination of alpha-glucosidase inhibitor and ribavirin for the treatment of Dengue virus infection in vitro and in vivo , 2011 .
[20] P. Shi,et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. , 2011, Antiviral research.
[21] D. Alonzi,et al. Inhibitors of Endoplasmic Reticulum α-Glucosidases Potently Suppress Hepatitis C Virus Virion Assembly and Release , 2010, Antimicrobial Agents and Chemotherapy.
[22] N. Zitzmann,et al. Targeting a host process as an antiviral approach against dengue virus. , 2010, Trends in Microbiology.
[23] M. Diamond,et al. Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification , 2010, PLoS pathogens.
[24] Ralf Bartenschlager,et al. Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites , 2009, Cell Host & Microbe.
[25] R. Moriarty,et al. Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses , 2009, Antimicrobial Agents and Chemotherapy.
[26] P. Yenchitsomanus,et al. Interaction of dengue virus envelope protein with endoplasmic reticulum-resident chaperones facilitates dengue virus production. , 2009, Biochemical and biophysical research communications.
[27] R. Dwek,et al. Iminosugars in Combination with Interferon and Ribavirin Permanently Eradicate Noncytopathic Bovine Viral Diarrhea Virus from Persistently Infected Cells , 2008, Antimicrobial Agents and Chemotherapy.
[28] R. Dwek,et al. Correction: The Mannose Receptor Mediates Dengue Virus Infection of Macrophages , 2008, PLoS Pathogens.
[29] R. Dwek,et al. The Mannose Receptor Mediates Dengue Virus Infection of Macrophages , 2008, PLoS pathogens.
[30] R. Dwek,et al. Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition. , 2008, The Biochemical journal.
[31] R. Dwek,et al. Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus , 2007, Hepatology.
[32] Wei Liu,et al. A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs. , 2007, The Journal of infectious diseases.
[33] R. Moriarty,et al. Antiviral Profiles of Novel Iminocyclitol Compounds against Bovine Viral Diarrhea Virus, West Nile Virus, Dengue Virus and Hepatitis B Virus , 2007, Antiviral chemistry & chemotherapy.
[34] E. Harris,et al. Murine Model for Dengue Virus-Induced Lethal Disease with IncreasedVascular Permeability , 2006, Journal of Virology.
[35] E. Harris,et al. S-Phase-Dependent Enhancement of Dengue Virus 2 Replication in Mosquito Cells, but Not in Human Cells , 2005, Journal of Virology.
[36] R. Dwek,et al. Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses. , 2005, Glycobiology.
[37] R. Doms,et al. Castanospermine, a Potent Inhibitor of Dengue Virus Infection In Vitro and In Vivo , 2005, Journal of Virology.
[38] P. Gage,et al. Dengue Virus M Protein C-Terminal Peptide (DVM-C) Forms Ion Channels , 2005, The Journal of Membrane Biology.
[39] R. Dwek,et al. Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling. , 2004, Analytical biochemistry.
[40] R. Dwek,et al. The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[41] M. James,et al. Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease. , 2003, Journal of molecular biology.
[42] R. Lachmann. Miglustat. Oxford GlycoSciences/Actelion. , 2003, Current opinion in investigational drugs.
[43] A. Nisalak,et al. High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. , 2002, The Journal of infectious diseases.
[44] R. Dwek,et al. Antiviral Effects of an Iminosugar Derivative on Flavivirus Infections , 2002, Journal of Virology.
[45] R. Dwek,et al. Study of the Mechanism of Antiviral Action of Iminosugar Derivatives against Bovine Viral Diarrhea Virus , 2001, Journal of Virology.
[46] R. Dwek,et al. Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: Therapeutic implications , 2001, Hepatology.
[47] Michael S. Diamond,et al. Modulation of Dengue Virus Infection in Human Cells by Alpha, Beta, and Gamma Interferons , 2000, Journal of Virology.
[48] R. Dwek,et al. Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis , 2000, The Lancet.
[49] P. Desprès,et al. α-Glucosidase Inhibitors Reduce Dengue Virus Production by Affecting the Initial Steps of Virion Morphogenesis in the Endoplasmic Reticulum , 2000, Journal of Virology.
[50] P. Emmerich,et al. Detection of Dengue Virus RNA in Patients after Primary or Secondary Dengue Infection by Using the TaqMan Automated Amplification System , 1999, Journal of Clinical Microbiology.
[51] P. D. Lilley,et al. Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. , 1998, Journal of medicinal chemistry.
[52] R. Dwek,et al. Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[53] T. Zor,et al. Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies. , 1996, Analytical biochemistry.
[54] R. Dwek,et al. N-butyldeoxygalactonojirimycin inhibits glycolipid biosynthesis but does not affect N-linked oligosaccharide processing. , 1994, The Journal of biological chemistry.
[55] R. Dwek,et al. N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis. , 1994, The Journal of biological chemistry.
[56] R. Dwek,et al. Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[57] G S Jacob,et al. Aminosugar derivatives as potential anti-human immunodeficiency virus agents. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[58] Paul W Smith,et al. Inhibition of HIV replication by amino‐sugar derivatives , 1988, FEBS letters.
[59] D. Jeffries,et al. CASTANOSPERMINE AND OTHER PLANT ALKALOID INHIBITORS OF GLUCOSIDASE ACTIVITY BLOCK THE GROWTH OF HIV , 1987, The Lancet.
[60] A. Sjoerdsma,et al. Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing. , 1987, Biochemical and biophysical research communications.
[61] A. Elbein,et al. Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin. , 1983, Biochemistry.
[62] L. Svennerholm,et al. A procedure for the quantitative isolation of brain gangliosides. , 1980, Biochimica et biophysica acta.
[63] D. Spencer. Letter: The role of lay visitors in hospitals. , 1974, Lancet.
[64] A. Nisalak,et al. A plaque reduction test for dengue virus neutralizing antibodies. , 1967, Journal of immunology.