Mesothelial/monocytic incidental cardiac excrescence: a case report and review of literature.

Mesothelial/monocytic incidental cardiac excrescence (MICE) is a rare and distinctive benign lesion often found during cardiac valve replacement. To date, 43 cases have been reported in the English literature. This lesion is important because of the potential for confusion with primary or metastatic malignancy. We report a case of MICE in a 47-year-old Chinese man with rheumatic heart disease whose MICE was discovered during mitral and aortic valve replacement. Histopathological examination of the lesion combined with immunohistochemistry confirmed the diagnosis of MICE.

[1]  A. Sezgin,et al.  Lesion of Aggregated Monocytes and Mesothelial Cells: Mesothelial/Monocytic Incidental Cardiac Lesion , 2013, Case reports in pathology.

[2]  N. Trendell-Smith,et al.  A case of mesothelial/monocytic incidental cardiac excrescence (MICE) associated with squamous cell carcinoma of lung. , 2012, Pathology.

[3]  N. Polat,et al.  Mesothelial/monocytic incidental cardiac excrescence in a patient with antiphospholipid syndrome. , 2011, Interactive cardiovascular and thoracic surgery.

[4]  J. Tyagi,et al.  Mesothelial/monocytic incidental cardiac excrescences (MICE) with tubercular aortitis: report of the first case with brief review of the literature , 2010, Journal of Clinical Pathology.

[5]  J. Wen,et al.  A case of mesothelial/monocytic incidental cardiac excrescence and literature review , 2010, Diagnostic pathology.

[6]  A. Dell’Amore,et al.  Cardiac mesothelial/monocytic-incidental-excrescence: more than an artifactual lesion? , 2008, Interactive cardiovascular and thoracic surgery.

[7]  Namvar Movahedi,et al.  Mesothelial/monocytic incidental cardiac excrescence. , 2008, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[8]  B. Adley,et al.  Nodular histiocytic ⁄ mesothelial hyperplasia on transthoracic biopsy : another source of potential pitfall in a lesion frequently present in spontaneous pneumothorax , 2007 .

[9]  P. Haghighi,et al.  A case of mesothelial/monocytic cardiac excrescence causing severe acute cardiopulmonary failure. , 2005, The American journal of surgical pathology.

[10]  B. Fang,et al.  Mesothelial/monocytic incidental cardiac excrescences of the heart: case report and literature review , 2004, International journal of clinical practice. Supplement.

[11]  J. Jagirdar,et al.  Nodular histiocytic/mesothelial hyperplasia: a potential pitfall. , 2004, Annals of diagnostic pathology.

[12]  R. D. de Gouveia,et al.  Cardiac MICE--tumor or thrombus? , 2003, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology.

[13]  T. Kitagawa,et al.  So-called mesothelial/monocytic incidental cardiac excrescences obtained during valve replacement surgery: report of three cases and literature review , 2000, Virchows Archiv.

[14]  A. Anderson,et al.  A report of mesothelial/monocytic incidental cardiac excrescences and a literature review. , 2000, Annals of diagnostic pathology.

[15]  R. Reid,et al.  Cardiac MICE—once seen never forgotten , 1999, Histopathology.

[16]  C. Yutani,et al.  Two cases of mesotheliaI/monocytic incidental cardiac excrescences of the heart , 1998, Pathology international (Print).

[17]  P. Argani,et al.  Metastatic adenocarcinoma involving a mesothelial/monocytic incidental cardiac excrescence (cardiac MICE) , 1997, The American journal of surgical pathology.

[18]  V. Walley,et al.  The clinical and pathologic manifestations of iatrogenically produced mesothelium-rich fragments of operative debris. , 1997, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[19]  V. Walley,et al.  Tissue Fragments Recovered at Cardiac Surgery Masquerading as Tumoral Proliferations: Evidence Suggesting Iatrogenic or Artefactual Origin and Common Occurrence , 1994, The American journal of surgical pathology.

[20]  W. Edwards,et al.  Mesothelial/monocytic incidental cardiac excrescences: cardiac MICE. , 1994, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[21]  R. Virmani,et al.  A Distinctive Cardiovascular Lesion Resembling Histiocytoid (Epithelioid) Hemangioma Evidence Suggesting Mesothelial Participation , 1990, The American journal of surgical pathology.

[22]  J. Rosai,et al.  The histiocytoid hemangiomas. A unifying concept embracing several previously described entities of skin, soft tissue, large vessels, bone, and heart. , 1979, Human pathology.