Enhancement of Penetration of Millimeter Waves by Field Focusing Applied to Breast Cancer Detection

Objective: The potentialities of improving the penetration of millimeter waves for breast cancer imaging are here explored. Methods: A field focusing technique based on a convex optimization method is proposed, capable of increasing the field level inside a breast-emulating stratification. Results: The theoretical results are numerically validated via the design and simulation of two circularly polarized antennas. The experimental validation of the designed antennas, using tissue-mimicking phantoms, is provided, being in good agreement with the theoretical predictions. Conclusion: The possibility of focusing, within a lossy medium, the electromagnetic power at millimeter-wave frequencies is demonstrated. Significance: Field focusing can be a key for using millimeter waves for breast cancer detection.

[1]  A. Freni,et al.  Automatic Design of CP-RLSA Antennas , 2012, IEEE Transactions on Antennas and Propagation.

[2]  N. Nikolova Microwave Imaging for Breast Cancer , 2011, IEEE Microwave Magazine.

[3]  E. Neufeld,et al.  IT’IS Database for Thermal and Electromagnetic Parameters of Biological Tissues , 2012 .

[4]  I. J. Craddock,et al.  Contrast-enhanced breast cancer detection using dynamic microwave imaging , 2012, Proceedings of the 2012 IEEE International Symposium on Antennas and Propagation.

[5]  Joachim Oberhammer,et al.  Millimeter-Wave Tissue Diagnosis: The Most Promising Fields for Medical Applications , 2015, IEEE Microwave Magazine.

[6]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries , 2007, Physics in medicine and biology.

[7]  P. Potier,et al.  Scalar near-field focusing in lossy media , 2017, 2017 International Conference on Electromagnetics in Advanced Applications (ICEAA).

[8]  Andrea Mazzanti,et al.  A mm-Wave 2D Ultra-Wideband Imaging Radar for Breast Cancer Detection , 2013 .

[9]  W. Barber,et al.  Comparison of linear and circular polarization for magnetic resonance imaging , 1985 .

[10]  C. Curtis,et al.  Microwave Breast Imaging With a Monostatic Radar-Based System: A Study of Application to Patients , 2013, IEEE Transactions on Microwave Theory and Techniques.

[11]  Robert A. Smith The Value of Modern Mammography Screening in the Control of Breast Cancer: Understanding the Underpinnings of the Current Debates , 2014, Cancer Epidemiology, Biomarkers & Prevention.

[12]  Ronan Sauleau,et al.  A Full-Wave Hybrid Method for the Analysis of Multilayered SIW-Based Antennas , 2013, IEEE Transactions on Antennas and Propagation.

[13]  A. Jemal,et al.  Cancer statistics, 2016 , 2016, CA: a cancer journal for clinicians.

[14]  Nancy L Keating,et al.  A systematic assessment of benefits and risks to guide breast cancer screening decisions. , 2014, JAMA.

[15]  Amir Ahmad Shishegar,et al.  Theoretical and experimental broadband tissue-equivalent phantoms at microwave and millimetre-wave frequencies , 2014 .

[16]  Lorenzo Crocco,et al.  On quantitative microwave tomography of female breast , 2009 .

[17]  Martin O’Halloran,et al.  Microwave Breast Imaging: Clinical Advances and Remaining Challenges , 2018, IEEE Transactions on Biomedical Engineering.

[18]  A. Jemal,et al.  Breast cancer statistics, 2013 , 2014, CA: a cancer journal for clinicians.

[19]  Andrea Mazzanti,et al.  On the Feasibility of Breast Cancer Imaging Systems at Millimeter-Waves Frequencies , 2017, IEEE Transactions on Microwave Theory and Techniques.

[20]  Mauro Ettorre,et al.  Tissue-mimicking materials for breast phantoms up to 50 GHz , 2019, Physics in medicine and biology.

[21]  Mark Coates,et al.  An Early Clinical Study of Time-Domain Microwave Radar for Breast Health Monitoring , 2016, IEEE Transactions on Biomedical Engineering.

[22]  K. Paulsen,et al.  Initial clinical experience with microwave breast imaging in women with normal mammography. , 2007, Academic radiology.

[23]  Carey M. Rappaport,et al.  Determination of Bolus Dielectric Constant for Optimum Coupling of Microwaves through Skin for Breast Cancer Imaging , 2008 .

[24]  Anabela Da Silva,et al.  Enhanced contrast and depth resolution in polarization imaging using elliptically polarized light , 2016, Journal of biomedical optics.

[25]  P. Summers,et al.  Towards mm-wave spectroscopy for dielectric characterization of breast surgical margins. , 2019, Breast.

[26]  K. Michalski,et al.  Multilayered media Green's functions in integral equation formulations , 1997 .

[27]  I. J. Craddock,et al.  Clinical trials of a multistatic UWB radar for breast imaging , 2011, 2011 Loughborough Antennas & Propagation Conference.

[28]  Maurizio Bozzi,et al.  Dielectric Properties Characterization From 0.5 to 50 GHz of Breast Cancer Tissues , 2017, IEEE Transactions on Microwave Theory and Techniques.

[29]  T. Kikkawa,et al.  Detectability of Breast Tumor by a Hand-held Impulse-Radar Detector: Performance Evaluation and Pilot Clinical Study , 2017, Scientific Reports.