Caffeine and brain development in very preterm infants

Caffeine improves neurological outcome in very preterm infants, but the mechanisms responsible for this neurological benefit are unknown. The objective of this study was to assess whether caffeine influenced brain macro‐ or microstructural development in preterm infants.

[1]  M. Paley,et al.  Diffusion‐weighted imaging of cerebral white matter and the cerebellum following preterm birth , 2010, Developmental medicine and child neurology.

[2]  U. Ådén,et al.  White matter changes in extremely preterm infants, a population‐based diffusion tensor imaging study , 2010, Acta paediatrica.

[3]  Simon K Warfield,et al.  MR‐determined hippocampal asymmetry in full‐term and preterm neonates , 2009, Hippocampus.

[4]  S. Pandya,et al.  Effect of caffeine and morphine on the developing pre-mature brain , 2008, Brain Research.

[5]  Simon K Warfield,et al.  Neonate hippocampal volumes: Prematurity, perinatal predictors, and 2‐year outcome , 2008, Annals of neurology.

[6]  M. Bogo,et al.  Maternal caffeine intake affects acetylcholinesterase in hippocampus of neonate rats , 2008, International Journal of Developmental Neuroscience.

[7]  L. Doyle,et al.  Long-term effects of caffeine therapy for apnea of prematurity. , 2007, The New England journal of medicine.

[8]  G. Casadesus,et al.  Neuroprotective effects of caffeine against complex I inhibition–induced apoptosis are mediated by inhibition of the Atm/p53/E2F‐1 path in cerebellar granule neurons , 2007, Journal of neuroscience research.

[9]  C. Verney,et al.  Transient Inhibition of Astrocytogenesis in Developing Mouse Brain Following Postnatal Caffeine Exposure , 2007, Pediatric Research.

[10]  P. Mareš,et al.  Effects of postnatal caffeine exposure on seizure susceptibility in developing rats , 2007, Brain Research.

[11]  Hwei-Hsien Chen,et al.  Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats , 2007, Psychopharmacology.

[12]  S. Rivkees,et al.  Protective effects of caffeine on chronic hypoxia‐induced perinatal white matter injury , 2006, Annals of neurology.

[13]  A. B. Silva-Gómez,et al.  Neonatal caffeine administration causes a permanent increase in the dendritic length of prefrontal cortical neurons of rats , 2006, Synapse.

[14]  Deanne K. Thompson,et al.  Perinatal risk factors altering regional brain structure in the preterm infant. , 2006, Brain : a journal of neurology.

[15]  T. Inder,et al.  Neonatal MRI to predict neurodevelopmental outcomes in preterm infants. , 2006, The New England journal of medicine.

[16]  L. Doyle,et al.  Caffeine therapy for apnea of prematurity. , 2006, The New England journal of medicine.

[17]  T. Nakamoto,et al.  Effects of Caffeine on the Saturated and Monounsaturated Fatty Acids of the Newborn Rat Cerebellum , 2004, Annals of Nutrition and Metabolism.

[18]  Ron Kikinis,et al.  Comparison of single-shot echo-planar and line scan protocols for diffusion tensor imaging. , 2004, Academic radiology.

[19]  Shu-Wei Sun,et al.  Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia , 2003, NeuroImage.

[20]  Steven P. Miller,et al.  Serial quantitative diffusion tensor MRI of the premature brain: Development in newborns with and without injury , 2002, Journal of magnetic resonance imaging : JMRI.

[21]  B. Gwag,et al.  Caffeine-induced neuronal death in neonatal rat brain and cortical cell cultures , 2002, Neuroreport.

[22]  H. Kinney,et al.  Arrested Oligodendrocyte Lineage Progression During Human Cerebral White Matter Development: Dissociation Between the Timing of Progenitor Differentiation and Myelinogenesis , 2002, Journal of neuropathology and experimental neurology.

[23]  S. Rivkees,et al.  Influences of adenosine on the fetus and newborn. , 2001, Molecular genetics and metabolism.

[24]  H. Kinney,et al.  Late Oligodendrocyte Progenitors Coincide with the Developmental Window of Vulnerability for Human Perinatal White Matter Injury , 2001, The Journal of Neuroscience.

[25]  B. Fredholm,et al.  Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. , 1999, Pharmacological reviews.

[26]  S. Maier,et al.  Microstructural Development of Human Newborn Cerebral White Matter Assessed in Vivo by Diffusion Tensor Magnetic Resonance Imaging , 1998, Pediatric Research.

[27]  B. Fredholm,et al.  The Effect of Long Term Caffeine Treatment on Hypoxic-Ischemic Brain Damage in the Neonate , 1995, Pediatric Research.

[28]  R. Guillet,et al.  Neonatal Caffeine Exposure and Seizure Susceptibility in Adult Rats , 1995, Epilepsia.

[29]  J. Kucharczyk,et al.  Identification of “Premyelination” by Diffusion‐Weighted MRI , 1995, Journal of computer assisted tomography.

[30]  B. Delpech,et al.  Caffeine Decreases Glial Cell Number and Increases Hyaluronan Secretion in Newborn Rat Brain Cultures , 1993, Pediatric Research.

[31]  G. Sutherland,et al.  The effects of caffeine on ischemic neuronal injury as determined by magnetic resonance imaging and histopathology , 1991, Neuroscience.

[32]  B. Zimmerberg,et al.  The effects of postnatal caffeine exposure on growth, activity and learning in rats , 1991, Pharmacology Biochemistry and Behavior.

[33]  H. Kinney,et al.  Sequence of Central Nervous System Myelination in Human Infancy. II. Patterns of Myelination in Autopsied Infants , 1988, Journal of neuropathology and experimental neurology.

[34]  P. Basser,et al.  Water Diffusion Changes in Wallerian Degeneration and Their Dependence on White Matter Architecture , 2000 .

[35]  P. Basser,et al.  Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. , 1996, Journal of magnetic resonance. Series B.

[36]  J. E. Tanner,et al.  Spin diffusion measurements : spin echoes in the presence of a time-dependent field gradient , 1965 .