[Opportunities for medication errors and pharmacist's interventions in the context of computerized prescription order entry: a review of data published by French hospital pharmacists].

Resume Introduction L’informatisation de la prescription se developpe en France. Elle contribue a reduire certaines erreurs medicamenteuses, mais les preuves d’un effet benefique sur les resultats cliniques restent limitees. Elle engendre aussi de nouveaux types d’erreurs. L’objectif de ce travail etait de rechercher les donnees francaises relatives a la nature et a la frequence des opportunites d’erreurs medicamenteuses generees par l’outil informatique et ayant conduit le pharmacien a intervenir aupres des prescripteurs. Materiels et methodes Nous avons effectue une recherche sur PubMed et CAT-INIST completee par une recherche manuelle. Resultats Dix publications, 11 abstracts et trois communications personnelles ont ete etudies. Dans le cadre de l’analyse des prescriptions informatisees, le taux d’interventions pharmaceutiques dues a l’informatique varie de 5,9 a 35 % selon les etudes. Les redondances de prescriptions, les erreurs d’unite, l’emploi du texte libre, les problemes de parametrage ainsi que l’ergonomie deficiente des logiciels sont a l’origine de nombreuses interventions pharmaceutiques. Certaines erreurs generees par l’outil informatique peuvent avoir des consequences potentielles severes. Discussion Les interventions pharmaceutiques dues a l’informatique sont frequentes. On ne sait pas si les variations des pourcentages d’interventions sont dues aux logiciels employes ou aux conditions de realisation des etudes. L’informatisation implique que les pharmaciens acquierent de nouveaux savoirs et de nouvelles competences afin de prevenir les erreurs de prescription generees par l’outil informatique. Conclusion Il est urgent de realiser des travaux destines a identifier les outils les plus surs et a ecarter les plus dangereux.

[1]  Jonathan M. Teich,et al.  The impact of computerized physician order entry on medication error prevention. , 1999, Journal of the American Medical Informatics Association : JAMIA.

[2]  Agnès Madic,et al.  Informatisation du circuit du médicament à l'hôpital : De l'intention à la réalisation , 2004 .

[3]  David W. Bates,et al.  Errors associated with outpatient computerized prescribing systems , 2011, J. Am. Medical Informatics Assoc..

[4]  M. Ward,et al.  Impact of health information technology on detection of potential adverse drug events at the ordering stage. , 2010, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[5]  M. Singer,et al.  Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit , 2005, Critical care.

[6]  C. Villanueva,et al.  Computerized physician order entry of injectable antineoplastic drugs: An epidemiologic study of prescribing medication errors , 2010, Int. J. Medical Informatics.

[7]  R. Kane,et al.  Just what the doctor ordered. Review of the evidence of the impact of computerized physician order entry system on medication errors. , 2007, Health services research.

[8]  D. Bates,et al.  Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. , 1998, JAMA.

[9]  P. Durieux,et al.  Impact of pharmacy validation in a computerized physician order entry context. , 2007, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[10]  C. Garrard,et al.  A comparison of handwritten and computer-assisted prescriptions in an intensive care unit , 1998, Critical care.

[11]  B. Charpiat,et al.  Problèmes médicamenteux les plus fréquemment détectés par l’analyse pharmacothérapeutique des prescriptions dans un centre hospitalier universitaire , 2010 .

[12]  Fred Pane,et al.  Pharmacist interventions in electronic drug orders entered by prescribers. , 2004, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[13]  P. Bonnabry.  Prescription informatisée et pharmacien hospitalier: quelles synergies ? , 2007 .

[14]  Monique W. M. Jaspers,et al.  Determination of the effectiveness of two methods for usability evaluation using a CPOE medication ordering system , 2011, Int. J. Medical Informatics.

[15]  Aaron M Cook,et al.  Medication-error reporting and pharmacy resident experience during implementation of computerized prescriber order entry. , 2007, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[16]  G J Kuperman,et al.  Patient safety and computerized medication ordering at Brigham and Women's Hospital. , 2001, The Joint Commission journal on quality improvement.

[17]  Paul N. Gorman,et al.  What's so special about medications: a pharmacist's observations from the POE study , 2001, AMIA.

[18]  Ross Koppel,et al.  What do we know about medication errors made via a CPOE system versus those made via handwritten orders? , 2005, Critical care.

[19]  J. Braithwaite,et al.  Effects of Two Commercial Electronic Prescribing Systems on Prescribing Error Rates in Hospital In-Patients: A Before and After Study , 2012, PLoS medicine.

[20]  Johanna I Westbrook,et al.  Review Paper: Does Computerized Provider Order Entry Reduce Prescribing Errors for Hospital Inpatients? A Systematic Review , 2009, J. Am. Medical Informatics Assoc..

[21]  Hardeep Singh,et al.  Prescription errors and outcomes related to inconsistent information transmitted through computerized order entry: a prospective study. , 2009, Archives of internal medicine.

[22]  B. Souleau,et al.  Drug administration error related to computerized prescribing , 2010, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

[23]  Genna R. Cohen,et al.  Are Electronic Medical Records Helpful for Care Coordination? Experiences of Physician Practices , 2010, Journal of General Internal Medicine.

[24]  J. Cantrill,et al.  Pharmacists’ Interventions in Prescribing Errors at Hospital Discharge , 2010, Drug safety.

[25]  A. O'Malley.  Tapping the unmet potential of health information technology. , 2011, The New England journal of medicine.

[26]  A. Potts,et al.  Computerized physician order entry and medication errors in a pediatric critical care unit. , 2004, Pediatrics.

[27]  B. Charpiat,et al.  Prescription informatisée et opportunités d'erreurs médicamenteuses Bilan d'un an d'observation dans deux unités de soins , 2011 .

[28]  D. Feldman,et al.  [To know, understand and combating medication errors related to computerized physician order entry]. , 2011, Annales pharmaceutiques francaises.

[29]  L. Cordero,et al.  Impact of Computerized Physician Order Entry on Clinical Practice in a Newborn Intensive Care Unit , 2004, Journal of Perinatology.

[30]  Joseph L. Kannry,et al.  Research Paper: Physician Satisfaction with Two Order Entry Systems , 2001, J. Am. Medical Informatics Assoc..

[31]  Matthew A. Eisenberg,et al.  Computerized Provider Order Entry Implementation: No Association With Increased Mortality Rates in an Intensive Care Unit , 2006, Pediatrics.

[32]  Chike Augustine Igboechi,et al.  Impact of Computerized Prescriber Order Entry on Medication Errors at an Acute Tertiary Care Hospital , 2003 .

[33]  A. Egberts,et al.  The Effect of Computerized Physician Order Entry on Medication Prescription Errors and Clinical Outcome in Pediatric and Intensive Care: A Systematic Review , 2009, Pediatrics.

[34]  Peter Hoonakker,et al.  Factors contributing to an increase in duplicate medication order errors after CPOE implementation , 2011, J. Am. Medical Informatics Assoc..

[35]  P. Michel,et al.  French national survey of inpatient adverse events prospectively assessed with ward staff , 2007, Quality and Safety in Health Care.

[36]  A. Localio,et al.  Role of computerized physician order entry systems in facilitating medication errors. , 2005 .

[37]  Remy R Coeytaux,et al.  Effect of a computerized prescriber-order-entry system on reported medication errors. , 2005, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[38]  Christian Lovis,et al.  Model Formulation: A Risk Analysis Method to Evaluate the Impact of a Computerized Provider Order Entry System on Patient Safety , 2008, J. Am. Medical Informatics Assoc..

[39]  Kirsten Colpaert,et al.  Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial , 2006, Critical care.

[40]  Enrique Seoane-Vazquez,et al.  Pharmacists' perceptions of computerized prescriber-order-entry systems. , 2007, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[41]  B. Allenet,et al.  Computerized physician order entry system combined with on-ward pharmacist: analysis of pharmacists' interventions. , 2012, Journal of evaluation in clinical practice.

[42]  R M Gardner,et al.  Impact of CPOE on Mortality Rates – Contradictory Findings, Important Messages , 2006, Methods of Information in Medicine.

[43]  Y. Han,et al.  Unexpected Increased Mortality After Implementation of a Commercially Sold Computerized Physician Order Entry System , 2005, Pediatrics.

[44]  Craig Senholzi,et al.  Pharmacist interventions after implementation of computerized prescriber order entry. , 2003, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[45]  Nicolette de Keizer,et al.  The impact of computerized physician medication order entry in hospitalized patients - A systematic review , 2008, Int. J. Medical Informatics.

[46]  Jon Wietholter,et al.  Effects of computerized prescriber order entry on pharmacy order-processing time. , 2009, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[47]  C. Zhan,et al.  Potential benefits and problems with computerized prescriber order entry: analysis of a voluntary medication error-reporting database. , 2006, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[48]  Steffie Woolhandler,et al.  Hospital computing and the costs and quality of care: a national study. , 2010, The American journal of medicine.

[49]  James D. Carpenter,et al.  Categorizing the unintended sociotechnical consequences of computerized provider order entry , 2007, Int. J. Medical Informatics.

[50]  A. Agustí,et al.  Obstacles and solutions for spontaneous reporting of adverse drug reactions in the hospital. , 2005, British journal of clinical pharmacology.

[51]  Monique W. M. Jaspers,et al.  A comparison of usability methods for testing interactive health technologies: Methodological aspects and empirical evidence , 2009, Int. J. Medical Informatics.

[52]  Dimitra I. Petrakaki,et al.  Implementation and adoption of nationwide electronic health records in secondary care in England: qualitative analysis of interim results from a prospective national evaluation , 2010, BMJ : British Medical Journal.

[53]  Ornella Conort,et al.  Interventions pharmaceutiques avant et après informatisation de la prescription dans un service de médecine interne , 2007 .

[54]  Clifford Wa.  A "KISS" EMR may be all you need. , 2009 .

[55]  Tom Chan,et al.  Are we setting about improving the safety of computerised prescribing in the right way? A workshop report. , 2009, Informatics in primary care.

[56]  B. Charpiat,et al.  Analyse pharmaceutique des prescriptions : Comparaison avant/après l'informatisation de la prescription au sein d'un service de chirurgie , 2006 .

[57]  R. Khajouei,et al.  Classification and prioritization of usability problems using an augmented classification scheme , 2011, J. Biomed. Informatics.

[58]  Andre Kushniruk,et al.  Increasing the safety of healthcare information systems through improved procurement: toward a framework for selection of safe healthcare systems. , 2010, Healthcare quarterly.