Effects of irreversible steps in computer models

[1]  H. Holzhütter,et al.  Use of mathematical models for predicting the metabolic effect of large-scale enzyme activity alterations. Application to enzyme deficiencies of red blood cells. , 1995, European journal of biochemistry.

[2]  J. Hofmeyr,et al.  Regulating the cellular economy of supply and demand , 2000, FEBS letters.

[3]  D. Fell,et al.  Metabolic control and its analysis , 1985 .

[4]  H V Westerhoff,et al.  'Slave' metabolites and enzymes. A rapid way of delineating metabolic control. , 2000, European journal of biochemistry.

[5]  G. Pettersson,et al.  A mathematical model of the Calvin photosynthesis cycle. , 1988, European journal of biochemistry.

[6]  R. Heinrich,et al.  The Regulation of Cellular Systems , 1996, Springer US.

[7]  B O Palsson,et al.  Metabolic dynamics in the human red cell. Part III--Metabolic reaction rates. , 1990, Journal of theoretical biology.

[8]  Reinhart Heinrich,et al.  Linear theory of enzymatic chains; its application for the analysis of the crossover theorem and of the glycolysis of human erythrocytes. , 1973, Acta biologica et medica Germanica.

[9]  A. Cornish-Bowden,et al.  Quantitative assessment of regulation in metabolic systems. , 1991, European journal of biochemistry.

[10]  A. Cornish-Bowden,et al.  Activation of nitrite reductase from Escherichia coli K12 by oxidized nicotinamide-adenine dinucleotide. , 1978, The Biochemical journal.

[11]  D. Kelly,et al.  Assimilation and toxicity of some exogenous C1 compounds, alcohols, sugars and acetate in the methane-oxidizing bacterium Methylococcus capsulatus. , 1973, Journal of general microbiology.

[12]  P W Kuchel,et al.  Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: equations and parameter refinement. , 1999, The Biochemical journal.

[13]  B. Hess,et al.  METABOLIC CONTROL MECHANISMS. VII.A DETAILED COMPUTER MODEL OF THE GLYCOLYTIC PATHWAY IN ASCITES CELLS. , 1964, The Journal of biological chemistry.

[14]  A. Cornish-Bowden,et al.  Prospects for Antiparasitic Drugs , 1998, The Journal of Biological Chemistry.

[15]  Peter N. Campbell,et al.  Biochemistry (2nd edn) , 1995 .

[16]  A. Cornish-Bowden,et al.  Isotope-exchange evidence for an ordered mechanism for rat-liver glucokinase, a monomeric cooperative enzyme. , 1981, Biochemistry.

[17]  A. Cornish-Bowden Fundamentals of Enzyme Kinetics , 1979 .

[18]  M. Bali,et al.  A modelling study of feedforward activation in human erythrocyte glycolysis. , 2001, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

[19]  D. E. Atkinson Cellular Energy Metabolism and its Regulation , 1977 .

[20]  D. Fell,et al.  Modelling photosynthesis and its control. , 2000, Journal of experimental botany.

[21]  J. H. Hofmeyr,et al.  The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models , 1997, Comput. Appl. Biosci..

[22]  Barbara M. Bakker,et al.  Compartmentation protects trypanosomes from the dangerous design of glycolysis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[23]  E. Newsholme,et al.  Regulation of Metabolism , 1973 .

[24]  Barbara M. Bakker,et al.  What Controls Glycolysis in Bloodstream Form Trypanosoma brucei?* , 1999, The Journal of Biological Chemistry.

[25]  Y. Shachar-Hill,et al.  Metabolic modeling identifies key constraints on an engineered glycine betaine synthesis pathway in tobacco. , 2000, Plant physiology.

[26]  Barbara M. Bakker,et al.  Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes* , 1997, The Journal of Biological Chemistry.

[27]  Reinhart Heinrich,et al.  A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. , 1974, European journal of biochemistry.

[28]  Pedro Mendes,et al.  GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems , 1993, Comput. Appl. Biosci..

[29]  D A Fell,et al.  Control analysis of mammalian serine biosynthesis. Feedback inhibition on the final step. , 1988, The Biochemical journal.

[30]  H M Sauro,et al.  SCAMP: a general-purpose simulator and metabolic control analysis program , 1993, Comput. Appl. Biosci..