Reduction of the grating lobes of annular arrays used in focused ultrasound surgery

An annular array with variable focus, used in focused ultrasound surgery, generates grating lobes responsible for undesirable lesions. It is known that the amplitude and the location of the lobes depend on both the geometry and the frequency of the transducer. A new procedure based on the use of a wide-band CW signal, i.e., a signal phase modulated by a pseudorandom code, is proposed to reduce the amplitude of these lobes. The theoretical study enables us to determine the location and the amplitude of these lobes and to simulate the effect of the transmitted signal bandwidth. In particular, a simple analytical relation gives the intensity ratio between the grating lobes and the main lobe. This equation shows that this ratio is inversely proportional to the number of rings and to the bandwidth of the transmitted signal. A system was developed and tested with two transducer arrays of 35- and 150-mm diameter, respectively. The simulations and experiments demonstrate the validity of the theoretical study and the efficacy of the proposed procedure. In conclusion, it is possible to reduce the grating lobes without geometric modification of the array by increasing the bandwidth of the transmitted signal.

[1]  P. Lenz,et al.  Reduction of cavitation using pseudorandom signals [therapeutic US] , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  C. Cain,et al.  Experimental evaluation of a prototype cylindrical section ultrasound hyperthermia phased-array applicator , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[3]  J. Y. Chapelon Pseudo-random correlation imaging and system characterization , 1988 .

[4]  J. Chapelon,et al.  Prostatic tissue destruction by high-intensity focused ultrasound: experimentation on canine prostate. , 1993, Journal of endourology.

[5]  J M Dubernard,et al.  Treatment of prostate cancer with transrectal focused ultrasound: early clinical experience. , 1996, European urology.

[6]  H. O'neil Theory of Focusing Radiators , 1949 .

[7]  M. Marberger,et al.  Tissue ablation in benign prostatic hyperplasia with high intensity focused ultrasound. , 1994, The Journal of urology.

[8]  W J FRY,et al.  Production of focal destructive lesions in the central nervous system with ultrasound. , 1954, Journal of neurosurgery.

[9]  F. Stuart Foster,et al.  Transient Fields of Concave Annular Arrays , 1981 .

[10]  E. Brookner Phased-array radars , 1985 .

[11]  Rémi Souchon,et al.  The feasibility of tissue ablation using high intensity electronically focused ultrasound , 1993 .

[12]  M. Marberger,et al.  Tissue ablation in benign prostatic hyperplasia with high-intensity focused ultrasound. , 1994, European urology.

[13]  C. Zanelli,et al.  Beamforming for therapy with high intensity focused ultrasound (HIFU) using quantitative schlieren , 1993 .

[14]  J P Donohue,et al.  High intensity focused ultrasound for the treatment of benign prostatic hyperplasia: early United States clinical experience. , 1994, The Journal of urology.

[15]  K. Hynynen The threshold for thermally significant cavitation in dog's thigh muscle in vivo. , 1991, Ultrasound in medicine & biology.

[16]  C. Cain,et al.  The sector-vortex phased array: acoustic field synthesis for hyperthermia , 1989, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.