Film-based delivery quality assurance for robotic radiosurgery: Commissioning and validation.

PURPOSE Robotic radiosurgery demands comprehensive delivery quality assurance (DQA), but guidelines for commissioning of the DQA method is missing. We investigated the stability and sensitivity of our film-based DQA method with various test scenarios and routine patient plans. We also investigated the applicability of tight distance-to-agreement (DTA) Gamma-Index criteria. METHODS AND MATERIAL We used radiochromic films with multichannel film dosimetry and re-calibration and our analysis was performed in four steps: 1) Film-to-plan registration, 2) Standard Gamma-Index criteria evaluation (local-pixel-dose-difference ≤2%, distance-to-agreement ≤2 mm, pass-rate ≥90%), 3) Dose distribution shift until maximum pass-rate (Maxγ) was found (shift acceptance <1 mm), and 4) Final evaluation with tight DTA criteria (≤1 mm). Test scenarios consisted of purposefully introduced phantom misalignments, dose miscalibrations, and undelivered MU. Initial method evaluation was done on 30 clinical plans. RESULTS Our method showed similar sensitivity compared to the standard End-2-End-Test and incorporated an estimate of global system offsets in the analysis. The simulated errors (phantom shifts, global robot misalignment, undelivered MU) were detected by our method while standard Gamma-Index criteria often did not reveal these deviations. Dose miscalibration was not detected by film alone, hence simultaneous ion-chamber measurement for film calibration is strongly recommended. 83% of the clinical patient plans were within our tight DTA tolerances. CONCLUSION Our presented methods provide additional measurements and quality references for film-based DQA enabling more sensitive error detection. We provided various test scenarios for commissioning of robotic radiosurgery DQA and demonstrated the necessity to use tight DTA criteria.

[1]  Guanghua Yan,et al.  On the sensitivity of patient‐specific IMRT QA to MLC positioning errors , 2009, Journal of applied clinical medical physics.

[2]  Todd Pawlicki,et al.  Cyberknife image-guided delivery and quality assurance. , 2008, International journal of radiation oncology, biology, physics.

[3]  C. Maurer,et al.  The CyberKnife® Robotic Radiosurgery System in 2010 , 2010, Technology in cancer research & treatment.

[4]  M. Oldham,et al.  An investigation of PRESAGE® 3D dosimetry for IMRT and VMAT radiation therapy treatment verification , 2015, Physics in medicine and biology.

[5]  E. Wilcox,et al.  Evaluation of GAFCHROMIC EBT film for Cyberknife dosimetry. , 2007, Medical physics.

[6]  A new correction method serving to eliminate the parabola effect of flatbed scanners used in radiochromic film dosimetry. , 2014, Medical physics.

[7]  Xiaodong Wu,et al.  Report of AAPM TG 135: quality assurance for robotic radiosurgery. , 2011, Medical physics.

[8]  Rob Barnett,et al.  Delivery quality assurance with ArcCHECK. , 2013, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[9]  B Poppe,et al.  On the sensitivity of common gamma-index evaluation methods to MLC misalignments in Rapidarc quality assurance. , 2013, Medical physics.

[10]  David Followill,et al.  Comparison of 2D and 3D gamma analyses. , 2014, Medical physics.

[11]  Yida Hu,et al.  Quantitative investigation of the effects of the scanning parameters in the digitization of EBT and EBT2 Gafchromic film dosimetry with flatbed scanners. , 2012, Journal of X-ray science and technology.

[12]  Christos Antypas,et al.  Performance evaluation of a CyberKnife® G4 image-guided robotic stereotactic radiosurgery system , 2008, Physics in medicine and biology.

[13]  A. Micke,et al.  Multichannel film dosimetry with nonuniformity correction. , 2011, Medical physics.

[14]  Subhash C. Sharma,et al.  Commissioning and acceptance testing of a CyberKnife linear accelerator , 2007, Journal of applied clinical medical physics.

[15]  M J Murphy,et al.  The Cyberknife: a frameless robotic system for radiosurgery. , 1997, Stereotactic and functional neurosurgery.

[16]  J J Wilkens,et al.  Comparison of Gafchromic EBT2 and EBT3 films for clinical photon and proton beams. , 2012, Medical physics.

[17]  Y. De Deene,et al.  Evaluation of radiochromic gel dosimetry and polymer gel dosimetry in a clinical dose verification , 2013, Physics in medicine and biology.

[18]  J. Dempsey,et al.  Important considerations for radiochromic film dosimetry with flatbed CCD scanners and EBT GAFCHROMIC® film. , 2006, Medical physics.

[19]  Oliver Jäkel,et al.  Analysis of uncertainties in Gafchromic® EBT film dosimetry of photon beams , 2008, Physics in medicine and biology.

[20]  Timothy C Zhu,et al.  Determination of correction factors for a 2D diode array device in MV photon beams. , 2009, Medical physics.

[21]  J. Mechalakos,et al.  IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119. , 2009, Medical physics.

[22]  Maria F Chan,et al.  An efficient protocol for radiochromic film dosimetry combining calibration and measurement in a single scan. , 2012, Medical physics.

[23]  P Francescon,et al.  Quality assurance of volumetric modulated arc therapy: evaluation and comparison of different dosimetric systems. , 2011, Medical physics.

[24]  Heng Li,et al.  Toward a better understanding of the gamma index: Investigation of parameters with a surface-based distance method. , 2011, Medical physics.

[26]  Steven D Chang,et al.  The use of TLD and Gafchromic film to assure submillimeter accuracy for image-guided radiosurgery. , 2008, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[27]  Benjamin E Nelms,et al.  Moving from gamma passing rates to patient DVH-based QA metrics in pretreatment dose QA. , 2011, Medical physics.

[28]  Fujio Araki,et al.  Angular dependence correction of MatriXX and its application to composite dose verification , 2012, Journal of applied clinical medical physics.

[29]  Weigang Hu,et al.  A spatially encoded dose difference maximal intensity projection map for patient dose evaluation: a new first line patient quality assurance tool. , 2011, Medical physics.

[30]  Panayiotis Mavroidis,et al.  Characterization of a novel 2D array dosimeter for patient-specific quality assurance with volumetric arc therapy. , 2013, Medical physics.