Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors

[1]  A Gulino,et al.  Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia , 2014, Leukemia.

[2]  C. Larsson,et al.  MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell Carcinoma , 2013, The Journal of investigative dermatology.

[3]  S. Fosså,et al.  Solid tumors after chemotherapy or surgery for testicular nonseminoma: a population-based study. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[4]  J. Brooks,et al.  Identification and Characterization of 2 Testicular Germ Cell Markers, Glut3 and CyclinA2 , 2013, Applied immunohistochemistry & molecular morphology : AIMM.

[5]  J. Brooks,et al.  Evaluation of SF-1 Expression in Testicular Germ Cell Tumors: A Tissue Microarray Study of 127 Cases , 2013, Applied immunohistochemistry & molecular morphology : AIMM.

[6]  C. Larsson,et al.  Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma , 2013, Endocrine-related cancer.

[7]  B. Nixon,et al.  The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets , 2013, F1000Research.

[8]  S. Murphy,et al.  Associations between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer , 2013, PloS one.

[9]  Sheila M. Reynolds,et al.  Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer. , 2013, Cancer cell.

[10]  A. Hussain,et al.  Testicular germ cell tumors: biology and clinical update , 2012, Current opinion in oncology.

[11]  C. Larsson,et al.  miR-205 Expression Promotes Cell Proliferation and Migration of Human Cervical Cancer Cells , 2012, PloS one.

[12]  H. Leffers,et al.  MicroRNA expression profiling of carcinoma in situ cells of the testis. , 2012, Endocrine-related cancer.

[13]  Wei Zhu,et al.  A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth , 2012, Oncogene.

[14]  J. Baron,et al.  A set of imprinted genes required for normal body growth also promotes growth of rhabdomyosarcoma cells , 2012, Pediatric Research.

[15]  R. Tibshirani,et al.  Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls , 2010, BMC Biology.

[16]  Anton J. Enright,et al.  Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. , 2010, Cancer research.

[17]  Mark D. Johnson,et al.  The Imprinted Gene PEG3 Inhibits Wnt Signaling and Regulates Glioma Growth* , 2010, The Journal of Biological Chemistry.

[18]  Zhen Lu,et al.  Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down‐regulated in human ovarian cancers by loss of heterozygosity and promoter methylation , 2008, Cancer.

[19]  Shao-Cong Sun,et al.  Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. , 2007, Developmental cell.

[20]  M. Louwman,et al.  Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  A. Fire,et al.  Patterns of known and novel small RNAs in human cervical cancer. , 2007, Cancer research.

[22]  Bing Su,et al.  Rapid evolution of an X-linked microRNA cluster in primates. , 2007, Genome research.

[23]  N. Perkins,et al.  Integrating cell-signalling pathways with NF-kappaB and IKK function. , 2007, Nature reviews. Molecular cell biology.

[24]  Mariette Schrier,et al.  A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors , 2006, Cell.

[25]  Shadan Ali,et al.  Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. , 2005, Cancer research.

[26]  K. Kosik,et al.  MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. , 2005, Cancer research.

[27]  N. Skakkebaek,et al.  Carcinoma in situ testis, the progenitor of testicular germ cell tumours: a clinical review. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.

[28]  G. Viglietto,et al.  Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors , 2005, Oncogene.

[29]  I. Sesterhenn,et al.  World health organization classifications of tumours. pathology and genetics of tumours of the urinary system and male genital organs , 2005 .

[30]  Kazuhiro Takahashi,et al.  Inhibition of NFκB Increases the Efficacy of Cisplatin in in Vitro and in Vivo Ovarian Cancer Models* , 2004, Journal of Biological Chemistry.

[31]  A. Clark,et al.  Human STELLAR, NANOG, and GDF3 Genes Are Expressed in Pluripotent Cells and Map to Chromosome 12p13, a Hotspot for Teratocarcinoma , 2004, Stem cells.

[32]  D. Bartel MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[33]  P. Woodward Tumours of the testis and paratesticular tissue , 2004 .

[34]  A. Marx,et al.  World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs , 2004 .

[35]  L. Looijenga,et al.  Expression of the PDGF α‐receptor 1.5 kb transcript, OCT‐4, and c‐KIT in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms , 2002, The Journal of pathology.

[36]  L. Looijenga,et al.  VASA Is a Specific Marker for Both Normal and Malignant Human Germ Cells , 2002, Laboratory Investigation.

[37]  L. Dunkel,et al.  Nuclear Factor-κB Activation in Human Testicular Apoptosis , 2002 .

[38]  L. Dunkel,et al.  Nuclear factor-kappa B activation in human testicular apoptosis. , 2002, The American journal of pathology.

[39]  H. Yoshioka,et al.  Epigenetic silencing of PEG3 gene expression in human glioma cell lines * , 2001, Molecular carcinogenesis.

[40]  X. Wu,et al.  Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[41]  C. Bokemeyer,et al.  Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis. , 2000, The American journal of pathology.

[42]  D. Bowtell,et al.  Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[43]  S. Seal,et al.  Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours , 2000, Nature Genetics.

[44]  D. Sassoon,et al.  Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway , 1998, Nature Genetics.

[45]  W. Greene,et al.  Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation , 1996, Molecular and cellular biology.

[46]  E. Mariman,et al.  Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors. , 1994, Journal of the National Cancer Institute.

[47]  E. R. Meyts,et al.  Expression of the c-kit protein product in carcinoma-in-situ and invasive testicular germ cell tumours , 1994 .