miR-122, a paradigm for the role of microRNAs in the liver.

[1]  F. Gonzalez,et al.  PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. , 2008, Toxicology.

[2]  Fan Zhou,et al.  Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas. , 2008, Mutation research.

[3]  S. Witting,et al.  Helper-dependent Adenovirus-mediated Short Hairpin RNA Expression in the Liver Activates the Interferon Response* , 2008, Journal of Biological Chemistry.

[4]  T. Patel,et al.  Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes , 2008, Oncogene.

[5]  Stefano Volinia,et al.  Interferon modulation of cellular microRNAs as an antiviral mechanism , 2007, Nature.

[6]  H. Yamada,et al.  Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride--regulating role of micro-RNA for RNA expression. , 2007, The Journal of toxicological sciences.

[7]  H. Bonkovsky,et al.  Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. , 2007, Gastroenterology.

[8]  Tsung-Cheng Chang,et al.  microRNAs in vertebrate physiology and human disease. , 2007, Annual review of genomics and human genetics.

[9]  K. Ghoshal,et al.  MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. , 2007, Gastroenterology.

[10]  Chris Sander,et al.  Cellular cofactors affecting hepatitis C virus infection and replication , 2007, Proceedings of the National Academy of Sciences.

[11]  X. Wang,et al.  Future of molecular profiling of human hepatocellular carcinoma. , 2007, Future oncology.

[12]  M. Feitelson,et al.  Hepatitis B virus integration, fragile sites, and hepatocarcinogenesis. , 2007, Cancer letters.

[13]  C. Croce,et al.  Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. , 2007, Cancer research.

[14]  C. Sander,et al.  A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing , 2007, Cell.

[15]  O. Kovalchuk,et al.  Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. , 2007, Mutation research.

[16]  Dong Kong,et al.  HBV-encoded microRNA candidate and its target , 2007, Comput. Biol. Chem..

[17]  T. Patel,et al.  The MicroRNA let-7a Modulates Interleukin-6-dependent STAT-3 Survival Signaling in Malignant Human Cholangiocytes* , 2007, Journal of Biological Chemistry.

[18]  H. Aburatani,et al.  Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. , 2006, Gene.

[19]  Karl T Kelsey,et al.  MicroRNA responses to cellular stress. , 2006, Cancer research.

[20]  K. Ghoshal,et al.  Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas , 2006, Journal of cellular biochemistry.

[21]  S. Pfeffer,et al.  Viruses, microRNAs and cancer , 2006, Oncogene.

[22]  W. Filipowicz,et al.  Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress , 2006, Cell.

[23]  Tushar Patel,et al.  Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. , 2006, Gastroenterology.

[24]  Theresa A. Storm,et al.  Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways , 2006, Nature.

[25]  T. Okanoue,et al.  Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues , 2006, Oncogene.

[26]  M. Czech MicroRNAs as therapeutic targets. , 2006, The New England journal of medicine.

[27]  S. Hammond MicroRNA therapeutics: a new niche for antisense nucleic acids. , 2006, Trends in molecular medicine.

[28]  N. Kato,et al.  Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response. , 2006, Gastroenterology.

[29]  C. Croce,et al.  A microRNA expression signature of human solid tumors defines cancer gene targets , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Mark Graham,et al.  miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. , 2006, Cell metabolism.

[31]  P. Marion,et al.  Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

[32]  N. Rajewsky,et al.  Silencing of microRNAs in vivo with ‘antagomirs’ , 2005, Nature.

[33]  K. Livak,et al.  Real-time quantification of microRNAs by stem–loop RT–PCR , 2005, Nucleic acids research.

[34]  Eugene Berezikov,et al.  Camels and zebrafish, viruses and cancer: a microRNA update. , 2005, Human molecular genetics.

[35]  P. Sarnow,et al.  Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA , 2005, Science.

[36]  Hong Jiang,et al.  Identification of human fetal liver miRNAs by a novel method , 2005, FEBS letters.

[37]  Kathryn A. O’Donnell,et al.  c-Myc-regulated microRNAs modulate E2F1 expression , 2005, Nature.

[38]  S. Lowe,et al.  A microRNA polycistron as a potential human oncogene , 2005, Nature.

[39]  C. Sander,et al.  Identification of microRNAs of the herpesvirus family , 2005, Nature Methods.

[40]  Ranit Aharonov,et al.  MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues. , 2004, Genome research.

[41]  V. Ambros The functions of animal microRNAs , 2004, Nature.

[42]  C. Sander,et al.  miR-122, a Mammalian Liver-Specific microRNA, is Processed from hcr mRNA and MayDownregulate the High Affinity Cationic Amino Acid Transporter CAT-1 , 2004, RNA biology.

[43]  D. Bartel,et al.  Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs , 2004, Nature Reviews Genetics.

[44]  Anton J. Enright,et al.  Identification of Virus-Encoded MicroRNAs , 2004, Science.

[45]  M. Buendia,et al.  Integration of woodchuck hepatitis and N‐myc rearrangement determine size and histologic grade of hepatic tumors , 2004, Hepatology.

[46]  C. Croce,et al.  Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[47]  V. Ambros,et al.  Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation , 2004, Genome Biology.

[48]  C. Burge,et al.  Prediction of Mammalian MicroRNA Targets , 2003, Cell.

[49]  Jinhong Chang,et al.  Resistance of Human Hepatitis Delta Virus RNAs to Dicer Activity , 2003, Journal of Virology.

[50]  E. De Clercq,et al.  Selective inhibition of hepatitis B virus replication by RNA interference. , 2003, Biochemical and biophysical research communications.

[51]  V. Ambros,et al.  MicroRNAs and Other Tiny Endogenous RNAs in C. elegans , 2003, Current Biology.

[52]  T. Tuschl,et al.  New microRNAs from mouse and human. , 2003, RNA.

[53]  M. Emi,et al.  Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. , 2002, Gene.

[54]  Eric J Wagner,et al.  Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. , 2002, Molecular cell.

[55]  T. Tuschl,et al.  Identification of Tissue-Specific MicroRNAs from Mouse , 2002, Current Biology.

[56]  T. Tuschl,et al.  Identification of Novel Genes Coding for Small Expressed RNAs , 2001, Science.

[57]  L. Lim,et al.  An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans , 2001, Science.

[58]  B. Reinhart,et al.  Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA , 2000, Nature.

[59]  Guan-Tarn Huang,et al.  Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions. , 1999, European journal of cancer.

[60]  Recent patent applications in microRNAs , 2008, Nature Biotechnology.

[61]  Ning Li,et al.  Hepatitis B virus is inhibited by RNA interference in cell culture and in mice. , 2007, Antiviral research.

[62]  R. Aharonov,et al.  Identification of hundreds of conserved and nonconserved human microRNAs , 2005, Nature Genetics.

[63]  M. Buendia,et al.  Structure and expression of hcr, a locus rearranged with c-myc in a woodchuck hepatocellular carcinoma. , 1989, Oncogene.