A reproductive and developmental toxicity screening study of 1,3-butadiene in Sprague-Dawley rats.

[1]  I. Brill,et al.  Mortality Among Men and Women in the North American Synthetic Rubber Industry, 1943-2009. , 2019, Journal of occupational and environmental medicine.

[2]  Raphael J Witorsch,et al.  Effects of elevated glucocorticoids on reproduction and development: relevance to endocrine disruptor screening , 2016, Critical reviews in toxicology.

[3]  M. Törnqvist,et al.  In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach. , 2014, Toxicology and applied pharmacology.

[4]  Ord,et al.  Integrated Risk Information System , 2013 .

[5]  Richard J. Albertini,et al.  1,3-Butadiene: II. Genotoxicity profile , 2010, Critical reviews in toxicology.

[6]  C. Kirman,et al.  1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment , 2010, Critical reviews in toxicology.

[7]  J. Holson,et al.  Assessing the toxicological significance of ejaculatory plugs as a clinical observation in rat toxicology studies: CNS-mediated increases in plug production vs. gustatory-mediated decreases in plug consumption. , 2010, Reproductive toxicology.

[8]  G P Daston,et al.  Inter-laboratory control data for reproductive endpoints required in the OPPTS 870.3800/OECD 416 reproduction and fertility test. , 2009, Birth defects research. Part B, Developmental and reproductive toxicology.

[9]  G. Csanády,et al.  Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats. , 2007, Chemico-biological interactions.

[10]  E W Carney,et al.  The effects of feed restriction during in utero and postnatal development in rats. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[11]  Keith A. Johnson,et al.  Effect of feed restriction on Hershberger and pubertal male assay endpoints. , 2003, Birth defects research. Part B, Developmental and reproductive toxicology.

[12]  A. Schuster,et al.  First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice. , 2001, Chemico-biological interactions.

[13]  R. Henderson,et al.  Disposition of butadiene epoxides in Sprague-Dawley rats following exposures to 8000 ppm 1,3-butadiene: comparisons with tissue epoxide concentrations following low-level exposures. , 1998, Toxicological sciences : an official journal of the Society of Toxicology.

[14]  D. Anderson,et al.  A comparison of male-mediated effects in rats and mice exposed to 1,3-butadiene. , 1998, Mutation research.

[15]  R. Henderson,et al.  Comparison of the disposition of butadiene epoxides in Sprague-Dawley rats and B6C3F1 mice following a single and repeated exposures to 1,3-butadiene via inhalation. , 1997, Toxicology.

[16]  S. C. Carpenter,et al.  In vitro metabolism of 4-vinylcyclohexene in rat and mouse liver, lung, and ovary. , 1997, Toxicology and applied pharmacology.

[17]  Diana Anderson,et al.  Male-mediated F1 effects in mice exposed to 1,3-butadiene. , 1996, Toxicology.

[18]  J. Doerr,et al.  Species difference in the ovarian toxicity of 1,3-butadiene epoxides in B6C3F1 mice and Sprague-Dawley rats. , 1996, Toxicology.

[19]  R. Henderson,et al.  Metabolism of 1,3-butadiene: species differences. , 1996, Toxicology.

[20]  R. Henderson,et al.  Gender differences in the metabolism of 1,3-butadiene in Sprague-Dawley rats following a low level inhalation exposure. , 1995, Carcinogenesis.

[21]  Smith Bj,et al.  OVARIAN TOXICITY OF 4-VINYLCYCLOHEXENE AND RELATED OLEFINS IN B6C3F1 MICE : ROLE OF DIEPOXIDES , 1995 .

[22]  R. Henderson,et al.  Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene. , 1995, Carcinogenesis.

[23]  J. A. Bond,et al.  High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene. , 1995, Toxicology and applied pharmacology.

[24]  J. A. Bond,et al.  Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation. , 1994, Carcinogenesis.

[25]  J. Teague,et al.  The Effects of Feed Restriction on Reproductive Function in Sprague-Dawley Rats , 1993 .

[26]  L. Strader,et al.  Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants. , 1992, Reproductive toxicology.

[27]  J. A. Bond,et al.  Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice. , 1992, Carcinogenesis.

[28]  J. Huff,et al.  1,3-Butadiene: toxicity and carcinogenicity in laboratory animals and in humans. , 1992, Reviews of environmental contamination and toxicology.

[29]  J. A. Bond,et al.  Toxicokinetics of inhaled 1,3-butadiene in monkeys: comparison to toxicokinetics in rats and mice. , 1991, Toxicology and applied pharmacology.

[30]  D. Mattison,et al.  Hepatic bioactivation of 4-vinylcyclohexene to ovotoxic epoxides. , 1991, Advances in experimental medicine and biology.

[31]  D. E. Carter,et al.  Comparison of the disposition and in vitro metabolism of 4-vinylcyclohexene in the female mouse and rat. , 1990, Toxicology and applied pharmacology.

[32]  D. Mattison,et al.  The role of epoxidation in 4-vinylcyclohexene-induced ovarian toxicity. , 1990, Toxicology and applied pharmacology.

[33]  P. E. Owen,et al.  Inhalation toxicity and carcinogenicity of 1,3-butadiene in Sprague-Dawley rats. , 1990, Environmental health perspectives.

[34]  M. G. Brown,et al.  Dominant lethal study in CD-1 mice following inhalation exposure to 1,3-butadiene: Final technical report , 1988 .

[35]  R. Westerberg,et al.  Sperm-head morphology study in B6C3F1 mice following inhalation exposure to 1,3-butadiene: Final technical report , 1988 .

[36]  J. A. Bond,et al.  Species differences in the distribution of inhaled butadiene in tissues. , 1987, American Industrial Hygiene Association journal.

[37]  I. Gaunt,et al.  Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats. , 1987, American Industrial Hygiene Association journal.

[38]  J. Collins,et al.  Toxicological evaluation of 4-vinylcyclohexene. I. Prechronic (14-day) and subchronic (13-week) gavage studies in Fischer 344 rats and B6C3F1 mice. , 1987, Journal of toxicology and environmental health.

[39]  J. Collins,et al.  Toxicological evaluation of 4-vinylcyclohexene. II. Induction of ovarian tumors in female B6C3F1 mice by chronic oral administration of 4-vinylcyclohexene. , 1987, Journal of toxicology and environmental health.

[40]  J. A. Bond,et al.  Species differences in the disposition of inhaled butadiene. , 1986, Toxicology and applied pharmacology.

[41]  W. Choy,et al.  In vivo sister chromatid exchange and micronucleus induction studies with 1,3-butadiene in B6C3F1 mice and Sprague-Dawley rats. , 1986, Mutagenesis.

[42]  B. E. Stewart,et al.  Potential indicators of reproductive toxicity: testicular sperm production and epididymal sperm number, transit time, and motility in Fischer 344 rats. , 1985, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[43]  J. L. Stuckhardt,et al.  Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing. , 1984, Teratogenesis, carcinogenesis, and mutagenesis.

[44]  K. Schärer.  The effect of chronic underfeeding on organ weights of rats. How to interpret organ weight changes in cases of marked growth retardation in toxicity tests? , 1977, Toxicology.

[45]  J. Orbach,et al.  Spontaneous seminal ejaculation and genital grooming in rats. , 1967, Brain research.

[46]  J. E. KIHLSTRÖM,et al.  Diurnal Variation in the Spontaneous Ejaculations of the Male Albino Rat , 1966, Nature.