Detailed mapping of ascorbate distribution in rat brain

Abstract Since only limited data were available on the distribution of ascorbic acid in rat brain, a detailed mapping was undertaken using a slice and semi-micro punching technique. The study provides new data on a number of rat brain regions; the most significant finding is that there are very marked gradients of ascorbate concentrations throughout the various nuclei. The possible correlation of the ascorbate levels with the various neurotransmitter systems is discussed.

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