Characteristics of the light transmitted through diffusing media: angular distribution and photon flux at the external boundary

The characteristics of the light transmitted through diffusing media have been studied by using the diffusion approximation of the radiative transfer equation. Making use of the partial-current-boundary condition an analytical expression for the angular dependence of the specific intensity emerging from a diffusing medium has been obtained. The analytical expression gives results in excellent agreement with Monte Carlo simulations for the slab geometry. The limits of validity of the theory have been investigated. Making use of the diffusion equation and of the extrapolated boundary condition, an heuristic analytical expression for the time-resolved reflectance has also been obtained assuming the photon flux as being simply proportional to the fluence rate. The proposed expression is simpler with respect to other commonly used expressions and seems to give better results when used to retrieve the optical properties from time-resolved measurements.

[1]  E. Gratton,et al.  Frequency-domain multichannel optical detector for noninvasive tissue spectroscopy and oximetry , 1995 .

[2]  M. Patterson,et al.  Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[3]  W. Press,et al.  Numerical Recipes: The Art of Scientific Computing , 1987 .

[4]  S R Arridge,et al.  The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis. , 1992, Physics in medicine and biology.

[5]  S R Arridge,et al.  An investigation of light transport through scattering bodies with non-scattering regions. , 1996, Physics in medicine and biology.

[6]  B. Wilson,et al.  A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo. , 1992, Medical physics.

[7]  B. Wilson,et al.  Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. , 1989, Applied optics.

[8]  L.H. Wang,et al.  Influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues , 1993, Proceedings of the 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Societ.

[9]  A Taddeucci,et al.  Photon migration through a turbid slab described by a model based on diffusion approximation. II. Comparison with Monte Carlo results. , 1997, Applied optics.