Viral latency and its regulation: lessons from the gamma-herpesviruses.

[1]  T. Günther,et al.  The Epigenetic Landscape of Latent Kaposi Sarcoma-Associated Herpesvirus Genomes , 2010, PLoS pathogens.

[2]  Nathaniel J. Moorman,et al.  Murine Gammaherpesvirus 68 LANA Is Essential for Virus Reactivation from Splenocytes but Not Long-Term Carriage of Viral Genome , 2010, Journal of Virology.

[3]  D. Ganem KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine. , 2010, The Journal of clinical investigation.

[4]  D. Ganem,et al.  Array-Based Transcript Profiling and Limiting-Dilution Reverse Transcription-PCR Analysis Identify Additional Latent Genes in Kaposi's Sarcoma-Associated Herpesvirus , 2010, Journal of Virology.

[5]  B. Cullen,et al.  A Human Herpesvirus MicroRNA Inhibits p21 Expression and Attenuates p21-Mediated Cell Cycle Arrest , 2010, Journal of Virology.

[6]  I. Tempera,et al.  Chromatin organization of gammaherpesvirus latent genomes. , 2010, Biochimica et biophysica acta.

[7]  Paul Kellam,et al.  KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. , 2010, Genes & development.

[8]  H. Virgin,et al.  Murine Gammaherpesvirus 68 Has Evolved Gamma Interferon and Stat1-Repressible Promoters for the Lytic Switch Gene 50 , 2010, Journal of Virology.

[9]  Yufei Huang,et al.  Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA , 2009, Nature Cell Biology.

[10]  W. Hammerschmidt,et al.  AP-1 homolog BZLF1 of Epstein–Barr virus has two essential functions dependent on the epigenetic state of the viral genome , 2009, Proceedings of the National Academy of Sciences.

[11]  D. Ganem,et al.  Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. , 2009, Cell host & microbe.

[12]  D. Vereide,et al.  Proof for EBV's sustaining role in Burkitt's lymphomas. , 2009, Seminars in cancer biology.

[13]  L. Frappier,et al.  Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2) , 2009, Journal of Cell Science.

[14]  Bryan R. Cullen,et al.  In-Depth Analysis of Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Expression Provides Insights into the Mammalian MicroRNA-Processing Machinery , 2009, Journal of Virology.

[15]  S. Speck,et al.  Gammaherpesvirus-Driven Plasma Cell Differentiation Regulates Virus Reactivation from Latently Infected B Lymphocytes , 2009, PLoS pathogens.

[16]  P. Chaudhary,et al.  Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. , 2009, Blood.

[17]  J. Anrather,et al.  Termination of NF-κB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligase , 2009, The EMBO journal.

[18]  L. T. Krug,et al.  NF-κB p50 Plays Distinct Roles in the Establishment and Control of Murine Gammaherpesvirus 68 Latency , 2009, Journal of Virology.

[19]  Jussi Taipale,et al.  KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA , 2009, PLoS pathogens.

[20]  H. Kung,et al.  NF-κB Serves as a Cellular Sensor of Kaposi's Sarcoma-Associated Herpesvirus Latency and Negatively Regulates K-Rta by Antagonizing the RBP-Jκ Coactivator , 2009, Journal of Virology.

[21]  K. Kaye,et al.  Role of Kaposi's Sarcoma-Associated Herpesvirus C-Terminal LANA Chromosome Binding in Episome Persistence , 2009, Journal of Virology.

[22]  B. Chandran,et al.  Kaposi's Sarcoma-Associated Herpesvirus Upregulates Angiogenin during Infection of Human Dermal Microvascular Endothelial Cells, Which Induces 45S rRNA Synthesis, Antiapoptosis, Cell Proliferation, Migration, and Angiogenesis , 2009, Journal of Virology.

[23]  H. Erfle,et al.  A Systems Biology Approach To Identify the Combination Effects of Human Herpesvirus 8 Genes on NF-κB Activation , 2009, Journal of Virology.

[24]  J. Brady,et al.  Gene Regulation and Functional Alterations Induced by Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORFK13/vFLIP in Endothelial Cells , 2008, Journal of Virology.

[25]  H. Hjalgrim,et al.  Infectious aetiology of Hodgkin and non‐Hodgkin lymphomas: a review of the epidemiological evidence , 2008, Journal of internal medicine.

[26]  D. Thorley-Lawson,et al.  The curious case of the tumour virus: 50 years of Burkitt's lymphoma , 2008, Nature Reviews Microbiology.

[27]  T. Schulz,et al.  Viral Inhibitor of Apoptosis vFLIP/K13 Protects Endothelial Cells against Superoxide-Induced Cell Death , 2008, Journal of Virology.

[28]  Shou-Jiang Gao,et al.  Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program. , 2008, Virology.

[29]  R. Sun,et al.  Regulation of Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Dopamine Receptor-Mediated Signaling Pathways , 2008, Journal of acquired immune deficiency syndromes.

[30]  C. Boshoff,et al.  Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome. , 2008, Molecular cell.

[31]  G. Stoecklin,et al.  Control of mRNA decay by phosphorylation of tristetraprolin. , 2008, Biochemical Society transactions.

[32]  D. Ganem,et al.  Effects of NFkappaB activation on KSHV latency and lytic reactivation are complex and context-dependent. , 2008, Virology.

[33]  J. Forrest,et al.  Establishment of B-Cell Lines Latently Infected with Reactivation-Competent Murine Gammaherpesvirus 68 Provides Evidence for Viral Alteration of a DNA Damage-Signaling Cascade , 2008, Journal of Virology.

[34]  C. Boshoff,et al.  KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor. , 2008, Blood.

[35]  K. Duca,et al.  Epstein-Barr virus: a paradigm for persistent infection - for real and in virtual reality. , 2008, Trends in immunology.

[36]  L. T. Krug,et al.  A gammaherpesvirus-secreted activator of Vβ4+ CD8+ T cells regulates chronic infection and immunopathology , 2008, The Journal of experimental medicine.

[37]  C. Rinaldo,et al.  Human Herpesvirus 8 Infects and Replicates in Primary Cultures of Activated B Lymphocytes through DC-SIGN , 2008, Journal of Virology.

[38]  X. Bustelo,et al.  The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly , 2008, PloS one.

[39]  Xiu-fen Lei,et al.  Kaposi's Sarcoma-Associated Herpesvirus Latent Gene vFLIP Inhibits Viral Lytic Replication through NF-κB-Mediated Suppression of the AP-1 Pathway: a Novel Mechanism of Virus Control of Latency , 2008, Journal of Virology.

[40]  N. Field,et al.  vFLIP from KSHV inhibits anoikis of primary endothelial cells , 2008, Journal of Cell Science.

[41]  Jeremy H. Herskowitz,et al.  Systematic Mutagenesis of the Murine Gammaherpesvirus 68 M2 Protein Identifies Domains Important for Chronic Infection , 2008, Journal of Virology.

[42]  Bryan R. Cullen,et al.  A viral microRNA functions as an orthologue of cellular miR-155 , 2007, Nature.

[43]  Jinshun Zhao,et al.  K13 Blocks KSHV Lytic Replication and Deregulates vIL6 and hIL6 Expression: A Model of Lytic Replication Induced Clonal Selection in Viral Oncogenesis , 2007, PloS one.

[44]  C. Gale,et al.  X Box Binding Protein XBP-1s Transactivates the Kaposi's Sarcoma-Associated Herpesvirus (KSHV) ORF50 Promoter, Linking Plasma Cell Differentiation to KSHV Reactivation from Latency , 2007, Journal of Virology.

[45]  J. Casey,et al.  RNA Editing of the Human Herpesvirus 8 Kaposin Transcript Eliminates Its Transforming Activity and Is Induced during Lytic Replication , 2007, Journal of Virology.

[46]  D. Thorley-Lawson,et al.  Plasma Cell-Specific Transcription Factor XBP-1s Binds to and Transactivates the Epstein-Barr Virus BZLF1 Promoter , 2007, Journal of Virology.

[47]  Alberto Riva,et al.  Kaposi's Sarcoma-Associated Herpesvirus Encodes an Ortholog of miR-155 , 2007, Journal of Virology.

[48]  K. Alitalo,et al.  Viral Oncogene–Induced DNA Damage Response Is Activated in Kaposi Sarcoma Tumorigenesis , 2007, PLoS pathogens.

[49]  J. Forrest,et al.  ORF73-Null Murine Gammaherpesvirus 68 Reveals Roles for mLANA and p53 in Virus Replication , 2007, Journal of Virology.

[50]  S. Chanda,et al.  B cell terminal differentiation factor XBP‐1 induces reactivation of Kaposi's sarcoma‐associated herpesvirus , 2007, FEBS letters.

[51]  B. Cullen,et al.  Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. , 2007, Virology.

[52]  G. Liao,et al.  The Kaposi's Sarcoma-Associated Herpesvirus LANA Protein Stabilizes and Activates c-Myc , 2007, Journal of Virology.

[53]  Jianhong Hu,et al.  Analysis of Viral cis Elements Conferring Kaposi's Sarcoma-Associated Herpesvirus Episome Partitioning and Maintenance , 2007, Journal of Virology.

[54]  Nai-Wan Hsiao,et al.  Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library. , 2007, Journal of virological methods.

[55]  D. Lukac,et al.  Direct Interactions of Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50/Rta Protein with the Cellular Protein Octamer-1 and DNA Are Critical for Specifying Transactivation of a Delayed-Early Promoter and Stimulating Viral Reactivation , 2007, Journal of Virology.

[56]  S. Kenney,et al.  X-Box-Binding Protein 1 Activates Lytic Epstein-Barr Virus Gene Expression in Combination with Protein Kinase D , 2007, Journal of Virology.

[57]  Alberto Riva,et al.  Identification of Cellular Genes Targeted by KSHV-Encoded MicroRNAs , 2007, PLoS pathogens.

[58]  A. Waisman,et al.  Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency in a Cell Type-Specific Manner , 2007, Journal of Virology.

[59]  S. Chanda,et al.  Systematic Identification of Cellular Signals Reactivating Kaposi Sarcoma–Associated Herpesvirus , 2007, PLoS pathogens.

[60]  M. Samols,et al.  Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman disease. , 2007, The Journal of infectious diseases.

[61]  Crystal L. Woodard,et al.  Kaposi's Sarcoma-Associated Herpesvirus LANA Protein Downregulates Nuclear Glycogen Synthase Kinase 3 Activity and Consequently Blocks Differentiation , 2007, Journal of Virology.

[62]  M. Ballestas,et al.  Determination of Kaposi's Sarcoma-Associated Herpesvirus C-Terminal Latency-Associated Nuclear Antigen Residues Mediating Chromosome Association and DNA Binding , 2007, Journal of Virology.

[63]  R. Siliciano,et al.  Experimental approaches to the study of HIV-1 latency , 2007, Nature Reviews Microbiology.

[64]  M. Ballestas,et al.  Kaposi's sarcoma herpesvirus C-terminal LANA concentrates at pericentromeric and peri-telomeric regions of a subset of mitotic chromosomes. , 2007, Virology.

[65]  L. T. Krug,et al.  Inhibition of NF-κB Activation In Vivo Impairs Establishment of Gammaherpesvirus Latency , 2007, PLoS pathogens.

[66]  D. Dittmer,et al.  Functional p53 Signaling in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas: Implications for Therapy , 2006, Journal of Virology.

[67]  S. Speck,et al.  Evidence for CDK-Dependent and CDK-Independent Functions of the Murine Gammaherpesvirus 68 v-Cyclin , 2006, Journal of Virology.

[68]  A. Krithivas,et al.  Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA , 2006, Proceedings of the National Academy of Sciences.

[69]  T. Schulz,et al.  Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G1 Cell CycleArrest , 2006, Journal of Virology.

[70]  S. Verma,et al.  KSHV encoded LANA upregulates Pim-1 and is a substrate for its kinase activity. , 2006, Virology.

[71]  M. Pickering,et al.  Deregulation of DNA Damage Signal Transduction by Herpesvirus Latency-Associated M2 , 2006, Journal of Virology.

[72]  P. Lieberman,et al.  Acetylation of the Latency-Associated Nuclear Antigen Regulates Repression of Kaposi's Sarcoma-Associated Herpesvirus Lytic Transcription , 2006, Journal of Virology.

[73]  Adam Grundhoff,et al.  A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. , 2006, RNA.

[74]  B. Cullen,et al.  Transcriptional Origin of Kaposi's Sarcoma-Associated Herpesvirus MicroRNAs , 2006, Journal of Virology.

[75]  S. Speck,et al.  Identification of Spliced Gammaherpesvirus 68 LANA and v-Cyclin Transcripts and Analysis of Their Expression In Vivo during Latent Infection , 2006, Journal of Virology.

[76]  K. Luger,et al.  The Nucleosomal Surface as a Docking Station for Kaposi's Sarcoma Herpesvirus LANA , 2006, Science.

[77]  Daniel L. Popkin,et al.  Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency , 2006, Journal of Virology.

[78]  Satoko Matsumura,et al.  Transcripts Encoding K12, v-FLIP, v-Cyclin, and the MicroRNA Cluster of Kaposi's Sarcoma-Associated Herpesvirus Originate from a Common Promoter , 2005, Journal of Virology.

[79]  T. Schulz,et al.  Brd2/RING3 Interacts with a Chromatin-Binding Domain in the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 (LANA-1) That Is Required for Multiple Functions of LANA-1 , 2005, Journal of Virology.

[80]  R. Sun,et al.  β-Adrenoreceptors Reactivate Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication via PKA-Dependent Control of Viral RTA , 2005, Journal of Virology.

[81]  Jae U. Jung,et al.  Characterization of the Kaposi's Sarcoma-Associated Herpesvirus K1 Signalosome , 2005, Journal of Virology.

[82]  J. Richardson,et al.  Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[83]  K. Murphy,et al.  CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNγ , 2005 .

[84]  M. Samols,et al.  Cloning and Identification of a MicroRNA Cluster within the Latency-Associated Region of Kaposi's Sarcoma-Associated Herpesvirus , 2005, Journal of Virology.

[85]  Blossom Damania,et al.  Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[86]  E. Robertson,et al.  Kaposi's Sarcoma-Associated Herpesvirus Reactivation Is Regulated by Interaction of Latency-Associated Nuclear Antigen with Recombination Signal Sequence-Binding Protein Jκ, the Major Downstream Effector of the Notch Signaling Pathway , 2005, Journal of Virology.

[87]  D. Aucoin,et al.  A Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50 Deletion Mutant Is Defective for Reactivation of Latent Virus and DNA Replication , 2005, Journal of Virology.

[88]  M. Skobe,et al.  Lymphatic dysfunction in transgenic mice expressing KSHV k-cyclin under the control of the VEGFR-3 promoter. , 2005, Blood.

[89]  R. Sun,et al.  Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[90]  S. Speck,et al.  Establishment and Maintenance of Long-Term Murine Gammaherpesvirus 68 Latency in B Cells in the Absence of CD40 , 2005, Journal of Virology.

[91]  C. Sander,et al.  Identification of microRNAs of the herpesvirus family , 2005, Nature Methods.

[92]  D. Ganem,et al.  The Kaposin B Protein of KSHV Activates the p38/MK2 Pathway and Stabilizes Cytokine mRNAs , 2005, Science.

[93]  D. McGeoch,et al.  On phylogenetic relationships among major lineages of the Gammaherpesvirinae. , 2005, The Journal of general virology.

[94]  D. Thorley-Lawson,et al.  Terminal Differentiation into Plasma Cells Initiates the Replicative Cycle of Epstein-Barr Virus In Vivo , 2005, Journal of Virology.

[95]  D. Wolf,et al.  KAPOSI'S SARCOMA–ASSOCIATED HERPESVIRUS: Clinical, Diagnostic, and Epidemiological Aspects , 2005, Critical reviews in clinical laboratory sciences.

[96]  Christopher J. Ott,et al.  The Amino Terminus of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Contains AT Hooks That Facilitate the Replication and Partitioning of Latent EBV Genomes by Tethering Them to Cellular Chromosomes , 2004, Journal of Virology.

[97]  Nathaniel J. Moorman,et al.  Identification of Candidate Gammaherpesvirus 68 Genes Required for Virus Replication by Signature-Tagged Transposon Mutagenesis , 2004, Journal of Virology.

[98]  S. Kenney,et al.  The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome , 2004, Nature Genetics.

[99]  S. Hayward,et al.  Viral interactions with the Notch pathway. , 2004, Seminars in cancer biology.

[100]  R. Sun,et al.  Generation of a Latency-Deficient Gammaherpesvirus That Is Protective against Secondary Infection , 2004, Journal of Virology.

[101]  P. Busson,et al.  EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies. , 2004, Trends in microbiology.

[102]  J. Hiscott,et al.  A requirement for NF-κB induction in the production of replication-competent HHV-8 virions , 2004, Oncogene.

[103]  K. Yamanishi,et al.  Accumulation of Heterochromatin Components on the Terminal Repeat Sequence of Kaposi's Sarcoma-Associated Herpesvirus Mediated by the Latency-Associated Nuclear Antigen , 2004, Journal of Virology.

[104]  P. Chaudhary,et al.  Activation of alternative NF-κB pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1β-converting enzyme inhibitory protein (vFLIP) , 2004 .

[105]  S. Verma,et al.  Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Inhibits Lytic Replication by Targeting Rta: a Potential Mechanism for Virus-Mediated Control of Latency , 2004, Journal of Virology.

[106]  E. Cesarman,et al.  KSHV vFLIP Is Essential for the Survival of Infected Lymphoma Cells , 2004, The Journal of experimental medicine.

[107]  S. Efstathiou,et al.  ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency. , 2003, The Journal of general virology.

[108]  Nathaniel J. Moorman,et al.  The Gammaherpesvirus 68 Latency-Associated Nuclear Antigen Homolog Is Critical for the Establishment of Splenic Latency , 2003, Journal of Virology.

[109]  Q. Tao,et al.  Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. , 2003, Clinical immunology.

[110]  S. Howell,et al.  KSHV vFLIP binds to IKK-γ to activate IKK , 2003, Journal of Cell Science.

[111]  R. Sun,et al.  Comparative Study of Regulation of RTA-Responsive Genes in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 , 2003, Journal of Virology.

[112]  W. Hammerschmidt,et al.  The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[113]  R. Sun,et al.  NF-κB Inhibits Gammaherpesvirus Lytic Replication , 2003, Journal of Virology.

[114]  S. Speck,et al.  Long-Term Latent Murine Gammaherpesvirus 68 Infection Is Preferentially Found within the Surface Immunoglobulin D-Negative Subset of Splenic B Cells In Vivo , 2003, Journal of Virology.

[115]  In-Jeong Kim,et al.  Maintenance of Long Term γ-Herpesvirus B Cell Latency Is Dependent on CD40-Mediated Development of Memory B Cells1 , 2003, The Journal of Immunology.

[116]  D. Ganem,et al.  Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[117]  D. Ganem,et al.  Host Range of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Cells , 2003, Journal of Virology.

[118]  J. Brady,et al.  Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Prolongs the Life Span of Primary Human Umbilical Vein Endothelial Cells , 2003, Journal of Virology.

[119]  W. Hammerschmidt,et al.  Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. , 2003, Cancer research.

[120]  G. McFadden,et al.  Poxvirus Immunomodulatory Strategies: Current Perspectives , 2003, Journal of Virology.

[121]  D. Dittmer Transcription profile of Kaposi's sarcoma-associated herpesvirus in primary Kaposi's sarcoma lesions as determined by real-time PCR arrays. , 2003, Cancer research.

[122]  C. Lim,et al.  Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus Functionally Interacts with Heterochromatin Protein 1* , 2003, The Journal of Biological Chemistry.

[123]  Frederick Y. Wu,et al.  A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma–associated herpesvirus latency , 2003, Nature Medicine.

[124]  D. Ganem,et al.  The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Permits Replication of Terminal Repeat-Containing Plasmids , 2003, Journal of Virology.

[125]  Frederick Y. Wu,et al.  Role of CCAAT/Enhancer-Binding Protein Alpha (C/EBPα) in Activation of the Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Lytic-Cycle Replication-Associated Protein (RAP) Promoter in Cooperation with the KSHV Replication and Transcription Activator (RTA) and RAP , 2003, Journal of Virology.

[126]  Y. Chung,et al.  Suppression of Tetradecanoyl Phorbol Acetate-Induced Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus by K1 Signal Transduction , 2002, Journal of Virology.

[127]  K. Kaye,et al.  The Kaposi's Sarcoma-Associated Herpesvirus K12 Transcript from a Primary Effusion Lymphoma Contains Complex Repeat Elements, Is Spliced, and Initiates from a Novel Promoter , 2002, Journal of Virology.

[128]  In-Jeong Kim,et al.  γ-Herpesvirus Latency Is Preferentially Maintained in Splenic Germinal Center and Memory B Cells , 2002, The Journal of experimental medicine.

[129]  Jianhong Hu,et al.  The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Supports Latent DNA Replication in Dividing Cells , 2002, Journal of Virology.

[130]  H. Virgin,et al.  Antibody to a Lytic Cycle Viral Protein Decreases Gammaherpesvirus Latency in B-Cell-Deficient Mice , 2002, Journal of Virology.

[131]  M. Fujimuro,et al.  Protein Interactions Targeting the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus to Cell Chromosomes , 2002, Journal of Virology.

[132]  P. Farrell,et al.  Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency , 2002, Journal of Virology.

[133]  C. Lim,et al.  Functional Dissection of Latency-Associated Nuclear Antigen 1 of Kaposi's Sarcoma-Associated Herpesvirus Involved in Latent DNA Replication and Transcription of Terminal Repeats of the Viral Genome , 2002, Journal of Virology.

[134]  N. Jones,et al.  The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo. , 2002, Cancer cell.

[135]  D. Ganem,et al.  The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. , 2002, Genes & development.

[136]  Jianhong Hu,et al.  Latency-associated Nuclear Antigen (LANA) Cooperatively Binds to Two Sites within the Terminal Repeat, and Both Sites Contribute to the Ability of LANA to Suppress Transcription and to Facilitate DNA Replication* , 2002, The Journal of Biological Chemistry.

[137]  H. Virgin,et al.  Immune Control of the Number and Reactivation Phenotype of Cells Latently Infected with a Gammaherpesvirus , 2002, Journal of Virology.

[138]  D. Dittmer,et al.  Charting Latency Transcripts in Kaposi's Sarcoma-Associated Herpesvirus by Whole-Genome Real-Time Quantitative PCR , 2002, Journal of Virology.

[139]  M. Eby,et al.  The Human Herpes Virus 8-encoded Viral FLICE Inhibitory Protein Physically Associates with and Persistently Activates the IκB Kinase Complex* , 2002, The Journal of Biological Chemistry.

[140]  S. Mittnacht,et al.  p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma , 2002, Oncogene.

[141]  A. Srinivasan,et al.  Human herpesvirus-8 encoded Kaposin: subcellular localization using immunofluorescence and biochemical approaches. , 2002, DNA and cell biology.

[142]  E. Robertson,et al.  The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus. , 2001, Virology.

[143]  B. Kempkes,et al.  Control of Epstein–Barr virus reactivation by activated CD40 and viral latent membrane protein 1 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[144]  Y. Geng,et al.  Identification of a Cellular Protein That Interacts and Synergizes with the RTA (ORF50) Protein of Kaposi's Sarcoma-Associated Herpesvirus in Transcriptional Activation , 2001, Journal of Virology.

[145]  Hong Li,et al.  Human Herpesvirus 8 (HHV-8)-Encoded Cytokines Induce Expression of and Autocrine Signaling by Vascular Endothelial Growth Factor (VEGF) in HHV-8-Infected Primary-Effusion Lymphoma Cell Lines and Mediate VEGF-Independent Antiapoptotic Effects , 2001, Journal of Virology.

[146]  D. Thorley-Lawson,et al.  Epstein-Barr virus: exploiting the immune system , 2001, Nature Reviews Immunology.

[147]  Jianhong Hu,et al.  DNA Binding and Modulation of Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus , 2001, Journal of Virology.

[148]  Jiguo Chen,et al.  Octamer-Binding Sequence Is a Key Element for the Autoregulation of Kaposi's Sarcoma-Associated Herpesvirus ORF50/Lyta Gene Expression , 2001, Journal of Virology.

[149]  B. Sugden,et al.  Establishment of an oriP Replicon Is Dependent upon an Infrequent, Epigenetic Event , 2001, Molecular and Cellular Biology.

[150]  P. Murphy,et al.  Kaposi’s Sarcoma-Associated Herpesvirus G Protein-Coupled Receptor Constitutively Activates NF-κB and Induces Proinflammatory Cytokine and Chemokine Production Via a C-Terminal Signaling Determinant , 2001, The Journal of Immunology.

[151]  Frederick Y. Wu,et al.  Spindle Cell Conversion by Kaposi's Sarcoma-Associated Herpesvirus: Formation of Colonies and Plaques with Mixed Lytic and Latent Gene Expression in Infected Primary Dermal Microvascular Endothelial Cell Cultures , 2001, Journal of Virology.

[152]  B. Dutia,et al.  Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice. , 2001, The American journal of pathology.

[153]  W. Hammerschmidt,et al.  Molecular virology of Epstein-Barr virus. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[154]  T. Piolot,et al.  Close but Distinct Regions of Human Herpesvirus 8 Latency-Associated Nuclear Antigen 1 Are Responsible for Nuclear Targeting and Binding to Human Mitotic Chromosomes , 2001, Journal of Virology.

[155]  C. Atzler,et al.  Signaling by human herpesvirus 8 kaposin A through direct membrane recruitment of cytohesin-1. , 2001, Molecular cell.

[156]  M. Ballestas,et al.  Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Mediates Episome Persistence through cis-Acting Terminal Repeat (TR) Sequence and Specifically Binds TR DNA , 2001, Journal of Virology.

[157]  M. Corbellino,et al.  Activation of latent Kaposi's sarcoma-associated herpesvirus by demethylation of the promoter of the lytic transactivator , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[158]  M. Tremblay,et al.  Human herpesvirus 8 viral FLICE-inhibitory protein inhibits Fas-mediated apoptosis through binding and prevention of procaspase-8 maturation. , 2001, Journal of human virology.

[159]  B. Chandran,et al.  Activation of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Lytic Replication by Human Cytomegalovirus , 2001, Journal of Virology.

[160]  P. Brown,et al.  Modulation of Cellular and Viral Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus , 2001, Journal of Virology.

[161]  P. Moore,et al.  Kaposi's Sarcoma-Associated Herpesvirus LANA2 Is a B-Cell-Specific Latent Viral Protein That Inhibits p53 , 2001, Journal of Virology.

[162]  A. Wald,et al.  Mucosal shedding of human herpesvirus 8 in men. , 2000, The New England journal of medicine.

[163]  A. Krithivas,et al.  Human Herpesvirus 8 LANA Interacts with Proteins of the mSin3 Corepressor Complex and Negatively Regulates Epstein-Barr Virus Gene Expression in Dually Infected PEL Cells , 2000, Journal of Virology.

[164]  C. Boshoff,et al.  The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma–E2F pathway and with the oncogene Hras transforms primary rat cells , 2000, Nature Medicine.

[165]  E. Cesarman,et al.  Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells. , 2000, Blood.

[166]  S. Mahajan,et al.  Carboxy Terminus of Human Herpesvirus 8 Latency-Associated Nuclear Antigen Mediates Dimerization, Transcriptional Repression, and Targeting to Nuclear Bodies , 2000, Journal of Virology.

[167]  N. Jones,et al.  Crystal structure of a gamma-herpesvirus cyclin-cdk complex. , 2000, The EMBO journal.

[168]  H. Virgin,et al.  The Murine Gammaherpesvirus 68 v-Cyclin Is a Critical Regulator of Reactivation from Latency , 2000, Journal of Virology.

[169]  Sara B. Hendrickson,et al.  Murine Gammaherpesvirus 68 Cyclin D Homologue Is Required for Efficient Reactivation from Latency , 2000, Journal of Virology.

[170]  J. Sample,et al.  Latent Murine γ-Herpesvirus Infection Is Established in Activated B Cells, Dendritic Cells, and Macrophages1 , 2000, The Journal of Immunology.

[171]  Neil Q. McDonald,et al.  Crystal structure of a γ‐herpesvirus cyclin–cdk complex , 2000 .

[172]  W. Hammerschmidt,et al.  The Epstein–Barr virus lytic program is controlled by the co‐operative functions of two transactivators , 2000, The EMBO journal.

[173]  B. Chandran,et al.  Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells. , 2000, The American journal of pathology.

[174]  G. Gaidano,et al.  PROLIFERATION IN HHV‐8 POSITIVE PRIMARY EFFUSION LYMPHOMAS IS ASSOCIATED WITH EXPRESSION OF HHV‐8 CYCLIN BUT INDEPENDENT OF P27/KIP1: ABSTRACT 39 , 2000, The American journal of pathology.

[175]  H. Virgin,et al.  Disruption of the Murine Gammaherpesvirus 68 M1 Open Reading Frame Leads to Enhanced Reactivation from Latency , 2000, Journal of Virology.

[176]  G. Nabel,et al.  p53 inhibition by the LANA protein of KSHV protects against cell death , 1999, Nature.

[177]  T. Schulz,et al.  Latent Nuclear Antigen of Kaposi’s Sarcoma-Associated Herpesvirus Interacts with RING3, a Homolog of theDrosophila Female Sterile Homeotic (fsh) Gene , 1999, Journal of Virology.

[178]  S. Speck,et al.  Differential Methylation of Epstein-Barr Virus Latency Promoters Facilitates Viral Persistence in Healthy Seropositive Individuals , 1999, Journal of Virology.

[179]  E. Robertson,et al.  The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells. , 1999, Virology.

[180]  D. Ganem,et al.  Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells , 1999, Journal of Virology.

[181]  L. Hood,et al.  Modulation of the NF-κB pathway by virally encoded Death Effector Domains-containing proteins , 1999, Oncogene.

[182]  P. Biberfeld,et al.  The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression Factors , 1999, The Journal of experimental medicine.

[183]  H. Virgin,et al.  Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection. , 1999, Current opinion in immunology.

[184]  Lijun Wu,et al.  A Complex Translational Program Generates Multiple Novel Proteins from the Latently Expressed Kaposin (K12) Locus of Kaposi’s Sarcoma-Associated Herpesvirus , 1999, Journal of Virology.

[185]  T. Kouzarides,et al.  Epstein-Barr Virus Nuclear Antigen 3C Interacts with Histone Deacetylase To Repress Transcription , 1999, Journal of Virology.

[186]  H. Virgin,et al.  B Cells Regulate Murine Gammaherpesvirus 68 Latency , 1999, Journal of Virology.

[187]  R. Majeti,et al.  Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[188]  C. Boshoff,et al.  Transcriptional analysis of human herpesvirus-8 open reading frames 71, 72, 73, K14, and 74 in a primary effusion lymphoma cell line. , 1999, Virology.

[189]  M. Ballestas,et al.  Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen. , 1999, Science.

[190]  E. van Marck,et al.  Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[191]  H. Virgin,et al.  Macrophages Are the Major Reservoir of Latent Murine Gammaherpesvirus 68 in Peritoneal Cells , 1999, Journal of Virology.

[192]  N. Jones,et al.  Overcoming inhibitions: subversion of CKI function by viral cyclins. , 1999, Trends in biochemical sciences.

[193]  Carl Liu,et al.  Three Distinct Regions of the Murine Gammaherpesvirus 68 Genome Are Transcriptionally Active in Latently Infected Mice , 1999, Journal of Virology.

[194]  P. Moore,et al.  Characterization and Cell Cycle Regulation of the Major Kaposi’s Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Latent Genes and Their Promoter , 1999, Journal of Virology.

[195]  C. Boshoff,et al.  Degradation of p27Kip cdk inhibitor triggered by Kaposi's sarcoma virus cyclin–cdk6 complex , 1999, The EMBO journal.

[196]  N. Jones,et al.  Modulation of p27Kip1 levels by the cyclin encoded by Kaposi's sarcoma‐associated herpesvirus , 1999 .

[197]  D. Ganem,et al.  Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. , 1998, Virology.

[198]  T. Ragoczy,et al.  The Epstein-Barr Virus Rta Protein Activates Lytic Cycle Genes and Can Disrupt Latency in B Lymphocytes , 1998, Journal of Virology.

[199]  A. Haase,et al.  A Cluster of Latently Expressed Genes in Kaposi’s Sarcoma-Associated Herpesvirus , 1998, Journal of Virology.

[200]  J. Haas,et al.  Persistent Infection of Epstein-Barr Virus-Positive B Lymphocytes by Human Herpesvirus 8 , 1998, Journal of Virology.

[201]  Jae U. Jung,et al.  Identification of an Immunoreceptor Tyrosine-Based Activation Motif of K1 Transforming Protein of Kaposi’s Sarcoma-Associated Herpesvirus , 1998, Molecular and Cellular Biology.

[202]  D. Thorley-Lawson,et al.  EBV persistence in memory B cells in vivo. , 1998, Immunity.

[203]  R. Sun,et al.  A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[204]  J. Brady,et al.  Identification of Kaposin (Open Reading Frame K12) as a Human Herpesvirus 8 (Kaposi’s Sarcoma-Associated Herpesvirus) Transforming Gene , 1998, Journal of Virology.

[205]  D. Ganem,et al.  Limited Transmission of Kaposi’s Sarcoma-Associated Herpesvirus in Cultured Cells , 1998, Journal of Virology.

[206]  W. Hammerschmidt,et al.  Epstein–Barr virus‐mediated B‐cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor , 1998, The EMBO journal.

[207]  N. Jones,et al.  Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins , 1997, Nature.

[208]  E. Kieff,et al.  The Epstein–Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-κB , 1997 .

[209]  P. Farrell,et al.  Epstein-Barr virus EBNA3C represses Cp, the major promoter for EBNA expression, but has no effect on the promoter of the cell gene CD21 , 1997, Journal of virology.

[210]  T. Chatila,et al.  Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene. , 1997, Trends in microbiology.

[211]  D. Ganem,et al.  The structure and coding organization of the genomic termini of Kaposi's sarcoma-associated herpesvirus. , 1997, Virology.

[212]  L. Corey,et al.  Transmissible Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in saliva of men with a history of Kaposi's sarcoma , 1997, Journal of virology.

[213]  D. Allen,et al.  Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells , 1997, Journal of virology.

[214]  C. Boshoff,et al.  The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1 , 1997, Journal of virology.

[215]  F. Behm,et al.  Pathogenesis of an Infectious Mononucleosis-like Disease Induced by a Murine γ-Herpesvirus: Role for a Viral Superantigen? , 1997, The Journal of experimental medicine.

[216]  J. Tschopp,et al.  Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors , 1997, Nature.

[217]  F. Neipel,et al.  Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin , 1997, Journal of virology.

[218]  E. Kieff,et al.  The Epstein-Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[219]  J. Strominger,et al.  Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency , 1997, Molecular and cellular biology.

[220]  A. Haase,et al.  Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells , 1997, Journal of virology.

[221]  J. Russo,et al.  Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[222]  W. Zhong,et al.  The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions , 1996, Journal of virology.

[223]  C. Meijer,et al.  Expression of epstein-barr virus encoded nuclear antigen 1 in benign and malignant tissues harbouring EBV. , 1996, Journal of clinical pathology.

[224]  L. Yoo,et al.  Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68 , 1996, Journal of virology.

[225]  R. Gallo,et al.  Absence of human herpesvirus 8 DNA sequences in neoplastic Kaposi's sarcoma cell lines. , 1996, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

[226]  S. Speck,et al.  oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines , 1996, Journal of virology.

[227]  D. Noonan,et al.  KSHV sequences in biopsies and cultured spindle cells of epidemic, iatrogenic and Mediterranean forms of Kaposi's sarcoma. , 1996, Research in virology.

[228]  M. Perricaudet,et al.  Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA , 1996, Journal of virology.

[229]  S. Kenney,et al.  Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[230]  C. Boshoff,et al.  Cyclin encoded by KS herpesvirus , 1996, Nature.

[231]  C. Sample,et al.  A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa , 1996, Journal of virology.

[232]  E. Kieff,et al.  EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes , 1996, Journal of virology.

[233]  N. Bendsøe,et al.  Human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) DNA in Kaposi's sarcoma lesions, AIDS Kaposi's sarcoma cell lines, endothelial Kaposi's sarcoma simulators, and the skin of immunosuppressed patients. , 1996, The American journal of pathology.

[234]  R. Watson,et al.  Epstein-Barr virus nuclear antigen 3C is a powerful repressor of transcription when tethered to DNA , 1996, Journal of virology.

[235]  M. McGrath,et al.  Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture , 1996, Nature Medicine.

[236]  J. Strominger,et al.  Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[237]  F. Sigaux,et al.  Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. , 1995, Blood.

[238]  E. Cesarman,et al.  Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. , 1995, The New England journal of medicine.

[239]  E. Kieff,et al.  Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa , 1995, Journal of virology.

[240]  J. Ambroziak,et al.  Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. , 1995, Science.

[241]  T. Honjo,et al.  Epstein‐Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP‐J kappa, the homologue of Drosophila Suppressor of Hairless. , 1994, The EMBO journal.

[242]  E. Kieff,et al.  The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[243]  P. Ling,et al.  Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa. , 1994, Science.

[244]  M. Blanar,et al.  The bZIP transactivator of Epstein-Barr virus, BZLF1, functionally and physically interacts with the p65 subunit of NF-kappa B , 1994, Molecular and cellular biology.

[245]  A. Nash,et al.  Interactions of murine gammaherpesvirus 68 with B and T cell lines. , 1993, Virology.

[246]  L. Young,et al.  Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells , 1993, The Journal of experimental medicine.

[247]  A. Nash,et al.  Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. , 1992, The Journal of general virology.

[248]  C. Sample,et al.  The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulated , 1992, Journal of virology.

[249]  D. Gutsch,et al.  Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter , 1992, Journal of virology.

[250]  E. Kieff,et al.  The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation , 1991, Journal of virology.

[251]  S. Pileri,et al.  Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[252]  J. Strominger,et al.  Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[253]  U. Nater,et al.  Epstein-Barr virus. , 1991, The Journal of family practice.

[254]  S. Speck,et al.  Alternative splicing dictates translational start in Epstein‐Barr virus transcripts. , 1990, The EMBO journal.

[255]  J. Strominger,et al.  Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[256]  J. Strominger,et al.  Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[257]  B. Griffin,et al.  Epstein-Barr virus latent gene expression during the initiation of B cell immortalization. , 1989, The Journal of general virology.

[258]  B. Sugden,et al.  A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection , 1989, Journal of virology.

[259]  C. Rooney,et al.  Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus , 1989, Journal of virology.

[260]  S. Hayward,et al.  Interaction of the lymphocyte-derived Epstein-Barr virus nuclear antigen EBNA-1 with its DNA-binding sites , 1989, Journal of virology.

[261]  M. Perricaudet,et al.  A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus , 1987, Journal of virology.

[262]  L. Young,et al.  Differences in B cell growth phenotype reflect novel patterns of Epstein‐Barr virus latent gene expression in Burkitt's lymphoma cells. , 1987, The EMBO journal.

[263]  D. Purtilo Epstein-Barr Virus: The Spectrum of Its Manifestations in Human Beings , 1987, Southern medical journal.

[264]  M. Perricaudet,et al.  Clustered alternative splice sites in Epstein-Barr virus RNAs. , 1987, Nucleic Acids Research.

[265]  J. Strominger,et al.  An Epstein-Barr virus transcript from a latently infected, growth-transformed B-cell line encodes a highly repetitive polypeptide. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[266]  D. Reisman,et al.  trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1 , 1986, Molecular and cellular biology.

[267]  G. Evan,et al.  Restricted expression of EBV latent genes and T‐lymphocyte‐detected membrane antigen in Burkitt's lymphoma cells. , 1986, The EMBO journal.

[268]  M. Perricaudet,et al.  Epstein-Barr virus mRNAs produced by alternative splicing. , 1986, Nucleic acids research.

[269]  E. Kieff,et al.  Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation site. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[270]  M. Perricaudet,et al.  An Epstein-Barr virus transcription unit is at least 84 kilobases long. , 1986, Nucleic acids research.

[271]  E. Kieff,et al.  An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells , 1985, Cell.

[272]  J. Strominger,et al.  Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[273]  D. Reisman,et al.  A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components , 1985, Molecular and cellular biology.

[274]  J. Countryman,et al.  Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[275]  D. Reisman,et al.  A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[276]  J. Svobodova,et al.  Isolation of five strains of herpesviruses from two species of free living small rodents. , 1980, Acta virologica.

[277]  V. Diehl,et al.  Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt Cells , 1967, Science.

[278]  D. Ganem,et al.  Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs , 2009, Nature Genetics.

[279]  C. Bangham,et al.  How does HTLV-I persist despite a strong cell-mediated immune response? , 2008, Trends in immunology.

[280]  A. Wald,et al.  Frequent and asymptomatic oropharyngeal shedding of human herpesvirus 8 among immunocompetent men. , 2007, The Journal of infectious diseases.

[281]  R. Ambinder Epstein-barr virus and hodgkin lymphoma. , 2007, Hematology. American Society of Hematology. Education Program.

[282]  Susan Peterson,et al.  Treatment implications of the latent reservoir for HIV-1. , 2007, Advances in pharmacology.

[283]  D. Ganem,et al.  Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. , 2007, The Journal of general virology.

[284]  R. Sun,et al.  Regulation of KSHV lytic gene expression. , 2007, Current topics in microbiology and immunology.

[285]  K. Murphy,et al.  CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNgamma. , 2005, Virology.

[286]  D. Ganem,et al.  Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis. , 2004, The Journal of clinical investigation.

[287]  P. Chaudhary,et al.  Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[288]  R. Sun,et al.  NF-kappaB inhibits gammaherpesvirus lytic replication. , 2003, Journal of virology.

[289]  M. Begon,et al.  The wood mouse is a natural host for Murid herpesvirus 4. , 2003, The Journal of general virology.

[290]  S. Howell,et al.  KSHV vFLIP binds to IKK-gamma to activate IKK. , 2003, Journal of cell science.

[291]  L. Szekely,et al.  Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions. , 2002, The Journal of general virology.

[292]  Aniel,et al.  KAPOSI’S SARCOMA–ASSOCIATED HERPESVIRUS-LIKE DNA SEQUENCES IN AIDS-RELATED BODY-CAVITY–BASED LYMPHOMAS , 2001 .

[293]  J. Sample,et al.  Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. , 2000, Journal of immunology.

[294]  Eston,et al.  ANTIBODIES TO BUTYRATE-INDUCIBLE ANTIGENS OF KAPOSI ’ S SARCOMA – ASSOCIATED HERPESVIRUS IN PATIENTS WITH HIV-1 INFECTION , 2000 .

[295]  N. Jones,et al.  Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirus. , 1999, The EMBO journal.

[296]  P. Latreille,et al.  Complete sequence and genomic analysis of murine gammaherpesvirus 68 , 1997, Journal of virology.

[297]  J. Saffitz,et al.  Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. , 1997, Nature medicine.

[298]  E. Kieff,et al.  The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[299]  L. Waltzer,et al.  RBP-J kappa repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2. , 1995, Nucleic acids research.

[300]  J. Strominger,et al.  Epstein-Barr virus transformation. , 1987, Progress in nucleic acid research and molecular biology.

[301]  J. Yates,et al.  Stable replication of plasmids derived from Epstein–Barr virus in various mammalian cells , 1985, Nature.

[302]  CCAAT/Enhancer-Binding Protein- (cid:2) Is Induced during the Early Stages of Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Lytic Cycle Reactivation and Together with the KSHV Replication and Transcription Activator (RTA) Cooperatively Stimulates the Viral RTA, MTA, and PAN Promoters , 2022 .