Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE

[1]  B. Wirth,et al.  TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo , 2020, bioRxiv.

[2]  S. Artandi,et al.  Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation , 2020, Cell reports.

[3]  Abdullahi Umar Ibrahim,et al.  Genome Engineering Using the CRISPR Cas9 System , 2019 .

[4]  J. Ferrell,et al.  Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease. , 2019, Molecular cell.

[5]  Y. Nominé,et al.  One-step affinity purification of fusion proteins with optimal monodispersity and biological activity: application to aggregation-prone HPV E6 proteins , 2018, Microbial Cell Factories.

[6]  Howard Y. Chang,et al.  An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1 , 2018, Cell.

[7]  Maximilian Haeussler,et al.  CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens , 2018, Nucleic Acids Res..

[8]  David R. Liu,et al.  Evolved Cas9 variants with broad PAM compatibility and high DNA specificity , 2018, Nature.

[9]  C. Boland Erratum to: Non-coding RNA: It’s Not Junk , 2017, Digestive Diseases and Sciences.

[10]  Matthew C. Canver,et al.  Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. , 2017, The Journal of Biological Chemistry.

[11]  Manraj S. Gill,et al.  Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo , 2016, Molecular and Cellular Biology.

[12]  Lin He,et al.  Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes* , 2016, The Journal of Biological Chemistry.

[13]  Howard Y. Chang,et al.  7SK-BAF axis controls pervasive transcription at enhancers , 2016, Nature Structural &Molecular Biology.

[14]  Howard Y. Chang,et al.  Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE , 2016, Nature Protocols.

[15]  Howard Y. Chang,et al.  Structural imprints in vivo decode RNA regulatory mechanisms , 2015, Nature.

[16]  Alexander F. Palazzo,et al.  Non-coding RNA: what is functional and what is junk? , 2015, Front. Genet..

[17]  David R. Liu,et al.  Efficient Delivery of Genome-Editing Proteins In Vitro and In Vivo , 2015 .

[18]  R. Conaway,et al.  Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes. , 2014, Journal of visualized experiments : JoVE.

[19]  T. Cech,et al.  Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT , 2014, Nucleic acids research.

[20]  Matthew C. Canver,et al.  Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells*♦ , 2014, The Journal of Biological Chemistry.

[21]  A. Simeone,et al.  Reorganization of enhancer patterns in transition from naive to primed pluripotency. , 2014, Cell stem cell.

[22]  Chris P Ponting,et al.  Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System , 2014, Cell reports.

[23]  J. Steitz,et al.  The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones , 2014, Cell.

[24]  Matthew C. Canver,et al.  Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9. , 2014, Journal of visualized experiments : JoVE.

[25]  David A. Scott,et al.  Genome engineering using the CRISPR-Cas9 system , 2013, Nature Protocols.

[26]  T. Cech,et al.  Many disease-associated variants of hTERT retain high telomerase enzymatic activity , 2013, Nucleic Acids Research.

[27]  Chris P. Ponting,et al.  Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System , 2013, Cell reports.

[28]  R. Reed,et al.  Small-scale nuclear extracts for functional assays of gene-expression machineries. , 2012, Journal of visualized experiments : JoVE.

[29]  H. Pickett,et al.  Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently , 2012, Molecular and Cellular Biology.

[30]  Seunghyun Park,et al.  HiTRACE: high-throughput robust analysis for capillary electrophoresis , 2011, Bioinform..

[31]  Martin Löwer,et al.  Digital Genome-Wide ncRNA Expression, Including SnoRNAs, across 11 Human Tissues Using PolyA-Neutral Amplification , 2010, PloS one.

[32]  Jeongsik Yong,et al.  Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. , 2010, Molecular cell.

[33]  Timothy D. Veenstra,et al.  A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis , 2009, Science.

[34]  Lili Wan,et al.  SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing , 2008, Cell.

[35]  R. Reddel,et al.  A sensitive direct human telomerase activity assay , 2008, Nature Methods.

[36]  T. Veenstra,et al.  Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly , 2008, Cell.

[37]  Katarzyna Sikora,et al.  Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. , 2007, Molecular cell.

[38]  K. Collins,et al.  Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs. , 2003, Molecular cell.

[39]  W. Filipowicz,et al.  Evidence against a mitochondrial location of the 7-2/MRP RNA in mammalian cells , 1992, Cell.

[40]  R. Roeder,et al.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.